Krish D. Singh

@magnetokrishio.bsky.social

MEG neuroscience researcher, CUBRIC veteran, Yorkshire born, lives in the ‘Diff. https://www.cardiff.ac.uk/people/view/238332-singh-krish

👁️🧠🧪 Vision takes time. But how does visual information flow through the human brain? Our new PLOS Computational Biology paper uses population receptive field (pRF) modelling to bring the spatial precision of fMRI to MEG, revealing the temporal dynamics of visual areas. 📖 doi.org/10.1371/jour...

Non-invasive mapping of the temporal processing hierarchy in the human visual cortex

Author summary Vision doesn’t happen instantaneously, but unfolds over time. While we understand a lot about how the brain processes visual space, understanding how the brain processes information ove...

doi.org

🧠 New work showing prominent and widespread 𝘪𝘯 𝘷𝘪𝘷𝘰 pre-synaptic terminal reductions in people with schizophrenia.🧠 nature.com/articles/s41... Strongest effects in left hemisphere, but synaptic loss didn't track with MRI grey matter alterations, but did align with..👇1/4

Widespread synaptic density loss in schizophrenia follows molecular and network architecture - Molecular Psychiatry

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

nature.com

🚨 New paper 🚨 Did you ever wonder if the spatial similarity of receptor PET maps matters for their use in molecular-informed fMRI analyses? Here we systematically investigate this. 🧵

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Doing a lit search and finding many recent papers still using the jet colormap 😭😭😭 Please don't use this colormap for anything because it's not perceptually uniform (changes of equal size don't look equal) and not friendly to people with variant colour vision. Some alternatives below... <thread>

a man singing into a microphone with the words " maybe it 's time to let the old ways die " above him

Alt: a man singing into a microphone with the words " maybe it 's time to let the old ways die " above him

media.tenor.com

Please repost! Our deadline is fast approaching for a 20-month postdoc position leading an fMRI project on the neurodevelopment of metacognition and curiosity. Join a great lab with fantastic collaborators! 🙂

Matthias Gruber@mjgruber.bsky.social · last yr.

Interested in curiosity and metacognition in childhood and adolescence? Join us at Cardiff University (UK) for a Postdoc position in an international collaboration with @yanafandakova.bsky.social (Germany) and @pyoudeyer.bsky.social (France). Please repost! #DevPsych #PsychSciSky #neuroskyence

Our latest cross-species 🐭👨 work is out today ▶️ science.org/doi/10.1126/... We show that 1️⃣ Brain connectivity in carriers of genetic alterations conferring high risk for #autism & #schizophrenia U-turns (hyper▶️ hypo) during adolescence 2️⃣ This switch is driven by synaptic remodeling Thread 🧵👇 1/n

Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome

Synaptic dysfunction underlies brain connectivity alterations in 22q11DS, a syndrome linked to neuropsychiatric disorders.

science.org

I've been working with the Wilson-Cowan neural mass model for a while now and, over time, I've accumulated a bunch of tools to explore/visualize it. I recently decided to collect it all into a github repository available here if anyone is interested: github.com/NeuroLife77/...

GitHub - NeuroLife77/Wilson_Cowan_analysis: Analytical derivations and numerical analyses associated with the Wilson-Cowan model

Analytical derivations and numerical analyses associated with the Wilson-Cowan model - NeuroLife77/Wilson_Cowan_analysis

github.com

Challenge: does FMRI have a future (apart from studies of development and ageing)? We want to know HOW the brain works and for that we need millisecond temporal resolution neuropixels, MEG, OPMs. After nearly 30 years of FMRI we know basically WHERE things happen.