Marcos Aranda

@marcosaranda.bsky.social

Studying effects of light on physiology and behavior | Postdoc at the Schmidt lab | Northwestern University

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

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Science peeps: Looks like SciENcv updated the digital certificate used to sign Biosketch and Current & Pending documents without notification. The old certificate expires Saturday, September 26, 2026. SciENcv docs before that date may fail validation in eRA Commons delaying or blocking submission.

New bioRxiv preprint! How does hormonal state shape decisions about danger? We show that threat avoidance in female mice is dynamically tuned by progesterone through a melanopsin-dependent visual circuit. Surprisingly, the same circuit drives opposite behavioral effects in males and females 🦅👁️🧠

Light gates hormonal modulation of threat avoidance in female mice

Animals must constantly calibrate the costs and benefits of exploration of an environment based on expectations of danger. These decisions are strongly shaped by past experience of perceived threats w...

biorxiv.org

My second paper as a postdoc in the lab of @tiffmschmidt.bsky.social is out! In this work, we developed a novel behavioral paradigm to study how light shapes long-term threat avoidance 🐭🦅 through a retina–thalamic–limbic circuit 👁️🧠 Excited to share it! 🙌🏼 👉🏼 www.nature.com/articles/s41...

Light tunes long-term threat avoidance behavior in male mice - Nature Communications

In this study, the authors describe how light shapes a long-term threat avoidance behavior via a visual circuit linking the eye with the limbic system in mice.

nature.com