Gregg gets it correct here. “New OMB grant rule” sounds nerdy. But this is a huge and insane plan. This is the Trump admin writing down their goal of fundamentally changing the relationship between government and society. Funding for everything will be taken over. 1/

Gregg Gonsalves@gregggonsalves.bsky.social · 2mo ago

My latest for @thenation.com. Russell Vought is on a mission. He wants to take over all federal grant making & re-make it in his image. He is a dangerous ideologue who wants to inflict trauma on the whole nation. He is cruel and he has a plan. Only we can stop him. www.thenation.com/article/poli...

Interesting study, + bonus for opening with a Jack London quote ″the tremendous cold had already driven the life out of his fingers. . . dead fingers could neither touch nor clutch.″

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2mo ago

Illusory cold desensitizes touch https://www.biorxiv.org/content/10.64898/2026.06.02.729707v1

no words www.thetransmitter.org/neurology/ex... @thetransmitter.bsky.social

Exclusive: Brain and spinal cord institute stops research

The Burke Neurological Institute, which aims to find treatments to repair the brain and spinal cord, ceased research operations on 22 May.

thetransmitter.org

Very happy to share the work of Ivan Linares +coauthors who carried this whole project from behavioral task development to long term imaging of striatal neurons through learning to analysis of their behavior-related activity and its flexibility over time. Well done all!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 3mo ago

Learning shapes neural codes for sensory-motor integration in the tail of the striatum https://www.biorxiv.org/content/10.64898/2026.05.05.722944v1

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

“offers interpretable alternatives to deep-learning-based foundation models” Exploiting correlations across trials and behavioral sessions to improve neural decoding: Neuron www.cell.com/neuron/fullt...

Exploiting correlations across trials and behavioral sessions to improve neural decoding

Animals share common patterns of brain activity across trials and sessions. Exploiting this shared structure improves the prediction of behavior from neural activity, scales across many sessions and b...

cell.com

Last year, Republicans gave ICE $75 BILLION – more than most militaries across the globe – while refusing to fund your health care. I fought it then and I’m fighting it now. I’m voting NO on DHS funding.

NSF - Forced reorg - POs down ~ 40% (DRP, most rotators not renewed, retirements) - Forced move (and we have to pack and clean) to a building with no furniture, little to no conference space for panels, inadequate 🛜, …) I personally love the boxes they gave us for packing. “Details matter” 🙃

Anybody else worried that because of the long standing Republican war on SNAP people are going to experience painful hunger. Lets do something. @nanopharmnc.bsky.social and i are going to donate to some local nc food banks. Join us! Gonna match up to $500.

After 13 years in the US, I’ve made the difficult decision to leave. Having packed up everything and rethought about priorities, rather painstakingly, while I’m sad to leave the life I’ve made here, I’m also relieved that I won’t have to plan my life around immigration policies anymore.

Thrilled that our paper is out today in Nature! www.nature.com/articles/s4...

Sensory expectations shape neural population dynamics in motor circuits

Nature - Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the...

nature.com

Is it candy? Nope, it is a spooky 👻 cleared mouse 🧠 used for #fluorescencefriday movies

🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity! We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have: (1) more corticospinal neurons (CSNs) (2) better hand dexterity (3) more dexterous climbing, which is linked to CSN number🧵

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 10mo ago

Evolutionary expansion of the corticospinal system is linked to dexterity in Peromyscus mice https://www.biorxiv.org/content/10.1101/2025.10.16.682851v1

The NIH institute director firing last Friday is very bad. I made a video explainer about why. Stay for last post, w link to @science.org story from @jocelynkaiser.bsky.social 1/4 🧪

I made a video about the shutdown, and why this government worker won’t be a pawn. When the president and Supreme Court are both acting lawlessly, Congress must stand up and stop it. US science is collapsing and Congress needs to act. 🧪 Full video here: www.instagram.com/reel/DP1tXXE...

basic research on wacky things like Gila monster venom are what gave us GLP-1 drugs that are treating diabetes, obesity, & addiction in new ways this piece from @whyy.org is great an analogy: navigation apps are great but don't tell you how to climb Mt. Everest & survive whyy.org/segments/oze...

How experiments with venom on guinea pig pancreases led to Ozempic

Elon Musk wants to cut funding for scientific research, but the weight loss drugs he promoted also came from government funded basic science.

whyy.org

Krista Koeller@kristalerista.bsky.social · 10mo ago

Dear funding agencies, I know we all want to discover the wonder drug that will cure the horrible diseases, but to do that, we need to invest in basic, unsexy, foundational research on how the systems work. Funding can’t all be drug development. Sincerely, Looking for basic research grants.

The Nobel Prizes, 5 of 6 having so far gone to US based scientists, are a reminder of why we must stand up for science against this horrid administration. Here are some great Scientist Activists to follow. go.bsky.app/14W5Rdk

👀“experience of a punished outcome generates a BLA representation that is selectively replayed when animals subsequently abort choice of the large/risky reward option.” ⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 10mo ago

Risk reshapes amygdala representation of choice https://www.biorxiv.org/content/10.1101/2025.10.06.680813v1

A big step in the work of postdoc Arlene George. Nice work Arlene!!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 10mo ago

Neuropathic pain drives time-dependent reorganization of corticostriatal circuits https://www.biorxiv.org/content/10.1101/2025.10.07.680927v1

Controlled Delivery of a Neurotrophic Factor in the Adult Mouse Brain Using Engineered Microglia https://www.biorxiv.org/content/10.1101/2025.10.06.680702v1

So many academics are on HB-1 visas. This is another attack by #RussellVought on universities and scientific research. Stop telling me anything this administration does is in good faith or with any sort of policy goal except destruction.

Justin Wolfers@justinwolfers.bsky.social · 11mo ago

Critical part of the President's new $100,000 charge for H1-B visas: The Administration can also offer a $100,000 discount to any person, company, or industry that it wants. Replacing rules with arbitrary discretion. Want visas? You know who to call and who to flatter.

And we are live! Excited to announce the 2025 Multi-Agent Behavior Challenge on cross-lab supervised action recognition in mice 🐁🐀🖱️ Running on Kaggle until December 15th, with a $50,000 prize pool going to the top five submissions! www.kaggle.com/competitions...

Stimulus-Dependent Dopamine Dynamics from LocusCoeruleus Axons https://www.biorxiv.org/content/10.1101/2025.09.15.676390v1

Whether or not you are a US scientist, you’ll know that this US administration’s reckless ideology endangers the entire globe - the trajectory of human civilization and all life on Earth. Scientists please sign.

AGU (American Geophysical Union)@agu.org · 11mo ago

The EPA’s endangerment finding is under threat. This peer-reviewed climate science is essential to protecting public health & regulating greenhouse gases. Scientists: add your name to AGU’s letter defending the science before 15 Sept. Sign on ➡️ buff.ly/yuUbZo4 #ClimateScience #ScienceIsEssential

Glorious whiskers too

Patrick Vallely@pjvphotography.bsky.social · 12mo ago

"Pat, why do you carry that ridiculous 600mm lens on long hikes?" Buddy, I can see mountains reflected in the eyes of a trailside pika.

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

All donations goes straight to the project (+10% bonus donation will be added if you use my referral link above) www.researchhub.com/fund/4309/ac...

Accelerating What We Know About OCD: From Genes to Mice t...

Accelerating What We Know About OCD: From Genes to Mice to Bet...

researchhub.com

‘ In response to a request for comment, Zhu told us, “I have retired and I am in Greenland. I do not have to talk to you.” ‘

Retraction Watch@retractionwatch.com · last yr.

Genomics pioneer George Church earns first retraction for anti-aging gene therapy paper @averyorrall.bsky.social reports

The biggest violent crime spree in Washington, DC, happened on January 6, 2021, and Trump pardoned hundreds of violent felons who were part of that.

Judd Legum@juddlegum.bsky.social · last yr.

TRUMP: Violent crime in DC is spiraling out of control so I'm deploying the National Guard REALITY: