Mark Goldberg 🧠
@markgoldbergmd.bsky.social
Professor of Neurology, UT Health San Antonio. Vascular neurology | Neuroscience | Research: stroke recovery, AI, long covid | Cat family | He, him
How does the brain control limb movement? In a new paper, Julia Kaiser et al. investigate the development of different populations of neurons that project to the brain stem and spinal cord, seen in this SmartSPIM video. Read the open access study: bit.ly/4y5YIH9 #FluorescenceFriday
I want to congratulate Microsoft Copilot. While it has failed in every task possible, it at least has its movie references correct.
On Sundays our busy Stroke Service stands ready to take on new challenges . . .
999 med students just matched to a #neurology residency program, the largest # of new neurologists ever! But: New cases every yr in the US: 90k -Parkinson 200k -epilepsy 800k -stroke 900k -Alzheimer Total living in the US: 1M -MS 1.1M -Parkinson 3.5M -active epilepsy 10M -dementia 45M -migraine
Here’s a great recap of #ISC26 International Stroke Conf from @befast.bsky.social. My meeting highlight: random march alongside the STORYVILLE STOMPERS and their leader! Also grateful for chance encounters with new and old friends - thanks for lighting up ideas for stroke science and practice.
Braydon Dymm, MD@befast.bsky.social · 6mo agoJazz on the Mississippi, 7:30 AM sessions, and a room full of stroke neurologists clapping at trial results. My #ISC26 recap for @americanheart.bsky.social
My @bmj.com article about my stroke recovery and the importance of communication by health care professionals, especially around time frames: www.bmj.com/content/391/...
Nice work by @tomohikotakei.bsky.social expands understanding of the corticospinal pathway in primate fine motor control.
Tomohiko Takei@tomohikotakei.bsky.social · 7mo agoOur paper is out in Science Advances! What makes primate hands so dexterous? We show that evolutionarily distinct spinal and cortical pathways work together to balance stability and flexibility, supporting remarkable primate hand control. www.science.org/doi/10.1126/...
Our paper is out in Science Advances! What makes primate hands so dexterous? We show that evolutionarily distinct spinal and cortical pathways work together to balance stability and flexibility, supporting remarkable primate hand control. www.science.org/doi/10.1126/...
Primate dexterous hand movements are controlled by functionally distinct premotoneuronal systems
Distinct spinal and cortical pathways coordinate muscle synergies and fine control to support primate dexterous hand movements.
science.org
New free resource for physicians! Post-stroke spasticity is frequently missed but early identification makes all the difference. AAPM&R’s new microlearning series helps physicians who don’t treat spasticity learn more on the topic! Start learning today: ow.ly/K0fz50Y9lmc
Understanding Post-Stroke Spasticity: Education for Advancing Provider Awareness
ow.ly
Disappointing news for treatment of central retinal artery occlusion (CRAO, “stroke of the eye”). A new randomized trial shows no benefit of IV tenecteplase vs aspirin when given within 4.5 hours of onset. Fewer than 25% of patients in either group recovered vision. www.nejm.org/doi/10.1056/...
Pleased to share our new publication in STROKE: @americanheart.bsky.social Scientific Statement on Early Recognition and Intervention for Poststroke Spasticity. We support advances in research, training and implementation toward earlier diagnosis and timely, innovative spasticity treatments.
Yesterday an interview was posted with Mike Lauer about the state of science. I strongly disagree with it. I will write more later. But for now: I agree w/ Lauer’s central points about budgets and paperwork and institutional incentives. But he seems to not realize the political minefield he is in.
“The system of funding science is fundamentally broken. In some respects, it’s been an unmitigated disaster. It was a house of cards, and it’s not surprising that it’s now falling apart.” -Mike Lauer, former director of extramural research 🧪 www.statecraft.pub/p/whats-wron...
What’s Wrong with NIH Grants?
“Science is fundamentally different than remodeling a kitchen”
statecraft.pub
Don’t miss the 2025 Stroke Review from bluesky’s vascular neurologist, Dr. Dymm, @befast.bsky.social!
Braydon Dymm, MD@befast.bsky.social · 9mo ago2025 was a landmark year for stroke neurology. From the MeVO trials to news of AI-driven systems of care and Factor XIa inhibitors on the horizon, the landscape of vascular neurology has shifted. Here's a month-by-month recap of the year! 🧵
Movie you’ve watched more than six times in a gif. Hard mode: no Star Wars, Marvel.
Jeremy Berg@jeremymberg.bsky.social · 9mo agoMovie you’ve watched more than six times in a gif. Hard mode: no Star Wars, Marvel. 1/5
Ancillary studies are open. We’re working hard to get these samples into your hands. Please apply. recovercovid.org/ancillary
RECOVER: Researching COVID to Enhance Recovery
The long-term effects of COVID are real. Join the NIH in the search for answers.
recovercovid.org
Jon Douglas@atranscendedman.bsky.social · 9mo agoThe RECOVER Initiative has collected over 1.4 million biosamples from nearly 30,000 people to help uncover how Long COVID affects the body and guide future diagnostics and treatments. recovercovid.org/news/over-14...
Did Apple Watch VO₂ max suddenly get way more flattering? Maybe something in the iOS 26 update? No explanation from Apple — but I’m not complaining.
Fellow scientists, enjoy this low-calorie treat from Nature Scientific Reports, topped with the very best #AI. Thanks @erikangner.com for brightening my holiday.
Erik Angner@erikangner.com · 10mo ago"Runctitiononal features"? "Medical fymblal"? "1 Tol Line storee"? This gets worse the longer you look at it. But it's got to be good, because it was published in Nature Scientific Reports last week: www.nature.com/articles/s41... h/t @asa.tsbalans.se
Thrilled to be at #sfn25 with some of the best #NeurorepairLab science ever! First up: a method to trace sparsely labeled, long distance neuronal projections across entire mouse spinal cords and brains. Sunday afternoon (today, board NN12). Cajal would be proud! eppro02.ativ.me/appinfo.php?...
EventPilot
eppro02.ativ.me
#NIH proposals due soon? Have you seen this? All upcoming deadlines will be extended. (Mine was … tomorrow.) grants.nih.gov/grants/guide...
New paper w/ Brian McGarry, Ashvin Gandhi, and Drew Wilcock in @jamainternalmed.com! Hospitals are complaining across the US that patients are "stuck" waiting for rehab beds at nursing homes when they are medically stable and ready for discharge. What is going on?? jamanetwork.com/journals/jam...
Dallas and New Hampshire researchers tested 128 long COVID patients with suspected dysautonomia. Despite heavy symptoms, most showed normal results. Only 16 percent met criteria for POTS, suggesting true autonomic dysfunction is uncommon. www.sciencedirect.com/science/arti...
Minimal Objective Autonomic Dysfunction in Long COVID
sciencedirect.com
US stroke neurologist here. Who can explain the new AI tool that tripled good outcomes and reduced treatment times by one hour, according to this article? From other sources it seems to be Brainomix CTA software - would that account for such a big improvement in overall recovery?
The Guardian@theguardian.com · last yr.Stroke centres in England given AI tool that will help 50% of patients recover
That’s what happened to Google search? Proof that one person really can change the world!
Mrs Dr Syd@mrsdrsyd.bsky.social · last yr.I can hear Ed Zitron chanting the name of Prabhakar Raghavan over and over again www.wheresyoured.at/the-men-who-...
Greatly appreciate this review of epigenetic mechanisms underlying regeneration competency only in young animals. Especially timely perspective for those of us puzzling over CNS repair.
Sumru Bayin@sumrubayin.bsky.social · last yr.Excited to share our recent viewpoint with @storerlab.bsky.social led by Kirsten Sadler, on epigenetic mechanisms of regenerative resilience. Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...
