I'm pleased to share our recent review describing mechanisms through which lipid droplets drive MASLD progression. journals.lww.com/hep/fulltext...

Please re-post! Time is almost up to register for the 2026 FASEB Lipid Droplet Meeting. Abstracts are due May 31, 2026. See link below, and join us for an amazing SRC lipid meeting July 26-30! #LipidSRC events.faseb.org/event/Lipid-...

Sharing our new paper in @jci.org showing a novel mechanism for fatty liver disease and its progression to inflammation and fibrosis involving non autophagy role of ULK1 www.jci.org/articles/vie...

Interested in lipids? Join us @ the 2026 FASEB Lipid Droplet: From Mechanisms to Disease Conference (July 26-30, Scottsdale, AZ). Registration is now open! events.faseb.org/event/Lipid-... We are co-locating with the FASEB Phospholipids SRC! Register for one to enjoy BOTH meetings!

Worked with a great team to organize @keystoneSymposia.bsky.social Fueling #MASH : #Metabolic Drivers & #Inflammatory Crosstalk, this April! Join us to explore emerging research in Vancouver! keysym.us/KSMASH26 #KSMASH26 Early Registration and Abstract deadline is in less than 2 weeks!

Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk | Keystone Symposia

Join us at the Keystone Symposia on Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk, April 2026, in Vancouver, with field leaders!

keysym.us

☕ @mikelangelipid.bsky.social @olzmannlab.bsky.social & co identify a #LipidDroplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of #ferroptosis. @berkeleymcb.bsky.social bit.ly/49mTeyF

FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - Nature Cell Biology

Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.

bit.ly

Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...

Quantitative imaging of lipid transport in mammalian cells - Nature

Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.

nature.com

Understanding the predictors of metabolic dysfunction-associated steatotic liver disease— ASCI member Peter Crawford & team suggest ketogenesis serves a protective role in MASLD-MASH progression via processes other than fat oxidation: buff.ly/f26w63M

Super excited to share our new publication identifying the food preservative, sorbic acid, as a new PTM. Even cooler is that the deacylation and acylation of this PTM is catalyzed by the non-canonical activity of Class I HDACs using free sorbate (not sorbyl-CoA) www.science.org/doi/10.1126/...

Sorbate induces lysine sorbylation through noncanonical activities of class I HDACs to regulate the expression of inflammation genes

Sorbic acid regulates inflammatory gene expression through the mechanism of lysine sorbylation.

science.org

We recently published @geroscience.bsky.social the development and validation of the mouse social frailty index (mSFI) link.springer.com/article/10.1... We now report a detailed step-by-step resource paper describing how to conduct the mSFI. bio-protocol.org/en/bpdetail?...

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

Dylan Duerre@dylanduerre.bsky.social · last yr.

Excited to share that work from my PhD is now available in @natmetabolism.bsky.social! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D. Link to paper: urldefense.com/v3/__https:/... A Thread (1/15)

What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAT: Emerging roles of Rab GTPases in the regulation of lipid droplet contact sites M Alonso @albertpol.bsky.social and Harriet P Lo www.sciencedirect.com/science/arti...

New from @MorieLAB.bsky.social! Neutral Lipids restrict DNA mobility!! 1. This has important implications for DNA repair in vivo, 2. also in vitro when you measure DNA breaks using the comet assay, beware! 3. And, we provide a fast new protocol overcoming this issue 😍 doi.org/10.1111/boc....

Neutral lipids restrict the mobility of broken DNA molecules during comet assays

This study reveals that neutral lipids (NL), naturally present in cells, become trapped within genomic DNA as a consequence of the standard execution of the comet assay, a technique used to measure D...

doi.org