1/2 The regulatory labyrinth for commercialisation of GE bacteria for deliberate env release eg bioremediation, biofertilization or disease control in the EU. Note that each of the 27 member states must emit an opinion & a vote 😱. No wonder the field is altogether stagnant at this side of the pond ☹️
Matic Kostanjsek
@matick.bsky.social
PhD candidate @WUR 🇳🇱 with a passion for microbes, metabolic engineering and (bio)sustainability 🧬🦠. 🇸🇮
Bridge recombinase enables versatile rewriting of bacterial genomes https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1
The first published article of my PhD. As described by @gerrich.bsky.social, we equipped R. sphaeroides with a MoClo system, characterized genetic elements, and applied a semi-automated approach for rapid strain construction. Such a nice collaboration!
Publication alert 🚨 A new Golden Gate MoClo toolbox for Rhodobacter sphaeroides is out and it's built on Zymo-Parts! @matick.bsky.social & Antoine took our framework and added many new genetic tools and a new automation angle. This adaptation is a dream come true for me. 1/10 🧪🧵
This is it. The act of science -like art- is not the output, it is the interaction and the process. What makes us the kind of scientists we are is how we approach the problem 🧪
It’s a common complaint to spend an afternoon reading papers in search of something that turns into half a sentence (that you delete next week) – I’d argue that the “foraging” benefits are real, only pay off if you’re engaging with the actual material, & worth the “inefficiency” to learn more.
Fantastic piece, and should be required reading (especially for university presidents, ahem). All of this "AI is the future" and "the gap between university and industry AI use and expertise!" always elides the fact that the tech is "mid" at best (@tressiemcphd.bsky.social) and more often just slop.
LLRX republished the blogpost www.llrx.com/2025/08/ai-s...
Something I've been wondering is what sort of settings the Baker lab is using to get these gorgeous PyMOL figures with? (I'm assuming it's PyMOL?)
🤩 Another Baker lab…