We’re excited to launch the Princeton Neuroscience Institute Open Science award! Apply or nominate your peers until August 14th!

Julie Fabre@juliefabre.bsky.social · 3w ago

We're launching the PNI Open Science Awards at @princetonneuro.bsky.social, a pilot program to recognize the tools, datasets, and protocols that advance open, reproducible neuroscience with @maxime-beau.bsky.social. This work is foundational to modern neuroscience but rarely gets formal credit.

How do the basal ganglia turn what you see into what you do? New preprint w/ @kenneth-harris.bsky.social, @flickerfusion.bsky.social & @carandinilab.net: we recorded across striatum, GPe & SNr in a Go/NoGo task. Striatum encodes which stimulus, GPe & SNr encode action. 🧵 biorxiv.org/content/10.6...

Let's put more scientists in Congress! Let's put THIS scientist in Congress! :) www.newyorker.com/magazine/202...

Sam Wang, Politician-in-Training

The neuroscientist went from analyzing elections to running for Congress. But can this rookie win over New Jersey locals—and Trump voters?

newyorker.com

Want to explore connectivity & projection patterns yourself, like we do here? We released brain_street_view to let you pick any injection site in the Allen Connectivity Atlas and visualize where it projects in your favorite region of interest: github.com/Julie-Fabre/brain_street_view

Julie Fabre@juliefabre.bsky.social · 4mo ago

How do the basal ganglia turn what you see into what you do? New preprint w/ @kenneth-harris.bsky.social, @flickerfusion.bsky.social & @carandinilab.net: we recorded across striatum, GPe & SNr in a Go/NoGo task. Striatum encodes which stimulus, GPe & SNr encode action. 🧵 biorxiv.org/content/10.6...

A tool from microsoft (so that’ll probaly be maintained) to convert a bunch of formats (pdf, docx, xlsx, pptx, but also images and audio!) into markdown to feed your fav LLM: github.com/microsoft/ma...

The US/Iran war and escalating rhetoric are already disrupting civilian life and academic infrastructure across the region. We drafted a letter in defense of academic life, and to mobilize concrete support for affected students, scholars, and collaborations. Please check Sepi’s message and sign.

Protect Academic Life in Iran

We, the undersigned academics and researchers from around the world, express our profound concern over recent military strikes on Iran, the retaliatory responses, and the reported impact on civilian l...

sites.google.com

Sepiedeh Keshavarzi @sepikeshavarzi.bsky.social · 4mo ago

When universities and research institutions become military targets, academics cannot remain silent. I co-initiated an open letter calling for global academic solidarity and support for affected students and scholars. Please share. to read and sign: sites.google.com/view/protect...

Mon. Mar. 16th, We've got an exciting line-up of scientists in cell type identification (@maxime-beau.bsky.social, Eva Dyer, Anna Lakunina), cell type-informed theory (@aditijh.bsky.social, @mehdiazabou.bsky.social), and cell type-dependent manifolds (@lmprida.bsky.social, Manu Valero)! #Cosyne2026

*Multi-region computations in the brain* When two regions are better than one... doi.org/10.1016/j.ne... #neuroskyence

Applications are open for the 2026 Paris Spring School of Imaging and Electrophysiology! It’s a great way to discover Paris (❤️) while learning a pretty wide range of techniques for neuroscience, in a fantastic environment. Share widely: parisneuro.ovh

Fred Ramsdell was parked at a campground in Montana on Monday when his wife suddenly started shouting. He first thought that maybe she had seen a grizzly bear. Instead, she had regained cell service and had seen a flood of text messages with the same news. “You just won the Nobel Prize!” she yelled.

Winning a Nobel Prize Interrupted His Off-the-Grid Vacation

Fred Ramsdell found out about his Nobel Prize nearly 12 hours after it was announced because he was on vacation in the Rockies.

nyti.ms

Neuropixels Ultra! By @steinmetzneuro.bsky.social, who led a big collaboration www.sciencedirect.com/science/arti...

Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings

To understand the neural basis of behavior, it is essential to sensitively and accurately measure neural activity at single-neuron and single-spike re…

sciencedirect.com

How does the brain decide? 🧠 Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc. After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up. rdcu.be/eGUrv

Transitions in dynamical regime and neural mode during perceptual decisions - Nature

Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...

nature.com

In neuroscience, we often try to understand systems by analyzing their representations — using tools like regression or RSA. But are these analyses biased towards discovering a subset of what a system represents? If you're interested in this question, check out our new commentary! Thread:

attractors are the new receptive fields

Konrad Kording@kordinglab.bsky.social · last yr.

Attractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...

🚀 We are excited to share that bombcell is now available in Python! 🐍 Automatically sort your units into good/MUA/noise/non-somatic using quality metrics and interpretable & adjustable classification thresholds. pip install and play around with our toy dataset: 🔗 github.com/Julie-Fabre/...

GitHub - Julie-Fabre/bombcell: Automated quality control, curation and neuron classification of spike-sorted electrophysiology data

Automated quality control, curation and neuron classification of spike-sorted electrophysiology data - Julie-Fabre/bombcell

github.com

I really recommend sending your students to the Paris Spring School, many imaging and ephys techniques are covered in pretty good depth and the atmosphere is consistently fantastic every year! And in such a setting! parisneuro.ovh

Desdemona Fricker@desdemonafricker.bsky.social · last yr.

Running Paris Spring School practicals this week! The fabulous @maxime-beau.bsky.social is teaching the ins and outs of Neuropixels recordings, with help from the brilliant Marin Dauguet and all the team. @upcite.bsky.social @sppin-cnrs.bsky.social #neuroscience 👩‍🔬🧠 parisneuro.ovh

we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team. publicusaresearchbenefits.com please share and re-share so we get more great stories in there!

🔊New resource: Bombcell, automated quality control for extracellular electrophysiology 💡This is an #opensource, user-friendly toolbox that streamlines quality control for spike sorting outputs. 👩‍🔬Develop by Julie M. J. Fabre 🔗Link: open-neuroscience.com/en/post/bomb... #OpenScience #Neuroscience

Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social ! We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠

Two UCL researchers, including Dr Julie Fabre (@uclqsion.bsky.social) have been named as Schmidt Science Fellows, an award given to 32 exceptional early career researchers worldwide. Congratulations to both Dr @juliefabre.bsky.social & Dr Almarri on this incredible achievement! 👏

UCL early career researchers selected as 2025 Schmidt Science Fellows

Two UCL researchers have been named as Schmidt Science Fellows, an award only given to 32 exceptional early career researchers worldwide.

buff.ly

How do we associate the flavors we experience during a meal 🍽️😋 with postingestive effects like food poisoning 🤢🤮 that arise much later? Our answer in @nature.com this week: Illness signals from the gut reactivate and strengthen flavor representations in the amygdala. 📄: nature.com/articles/s41...

A neural mechanism for learning from delayed postingestive feedback - Nature

Illness signals from the gut reactivate and strengthen flavour representations in the amygdala to support learning from delayed postingestive feedback.

nature.com

Many of us use 2p scopes to image 3D volumes of brain. But then we analyze the data plane by plane, resulting in duplicated neurons, missed neurons, and low s/n. Let's go 3D! Suite3D: Volumetric cell detection for two-photon microscopy by @haydari.bsky.social & team. www.biorxiv.org/content/10.1...

First off, Bombcell is a MATLAB package (python version coming) developed by @juliefabre.bsky.social. It uses several metrics, like waveform shape, spike amplitudes and drift, to determine whether a detected unit is noise, multi-unit activity, axonal or a single neuron. github.com/Julie-Fabre/...

GitHub - Julie-Fabre/bombcell: Automated quality control, curation and neuron classification of spike-sorted electrophysiology data

Automated quality control, curation and neuron classification of spike-sorted electrophysiology data - Julie-Fabre/bombcell

github.com

It was an honour, thank you @rezashadmehr.bsky.social for organizing this great seminar series! Talk link: m.youtube.com/watch?v=zy0v...

Maxime Beau: Cell classification for the cerebellum

YouTube video by Shadmehr Lab

m.youtube.com

Reza Shadmehr@rezashadmehr.bsky.social · last yr.

Silicon probes enable large-scale neural recordings, but limited information on neuron identity. Maxime will present methods for identifying cell-types in the cerebellum, verified by opto-tagging. @maxime-beau.bsky.social Seminars are open to all (email me).

1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!

Individual variability of neural computations underlying flexible decisions - Nature

Behavioural experiments to study decision-making in response to context-dependent accumulation of evidence provide testable models that are consistent with the heterogeneity in neural signatures among...

nature.com

control is a complimentary approach to alignment. its really sensible, practical and can be done now, even before systems are superintelligent. youtu.be/6Unxqr50Kqg?...

Controlling powerful AI

YouTube video by Anthropic

youtu.be

The International Brain Laboratory reproducibility platform paper is now published at eLife. An amazing effort by many different labs and individuals to understand and improve the reproducibility of electrophysiological measurements in mice. 🧠

🚨 New paper alert! 🚨 We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species. A 🧵👇 (1/9)