Michael Honigberg
@mchonig.bsky.social
Cardiologist and researcher at Mass General / Broad Institute / Harvard Med. Preventive cardiology, women’s health, genomics. https://honigberglab.mgh.harvard.edu/
🚀 Issue #12 90-Second Cardio-OB Journal Scan with @cardioobdoc.bsky.social Blood Pressure Genetic Risk and Incident Hypertension after Pregnancy 🗞️ Apr 20, 2026 article @jama.com 🔗 jamanetwork.com/journals/jam... #ACCRepOB #ACCCardioOB #CardioObstetrics #CardioSky
In a US cohort, higher systolic #BloodPressure genetic risk was associated with new-onset #Hypertension after pregnancy, but elevated postpartum body mass index and hypertensive disorders of pregnancy were stronger risk factors. ja.ma/4s7jJxK
📣 We’re hiring! My team at Mass General Brigham / @broadinstitute.org is growing: • Postdoc (PhD; human 🧬 & multi-omics) • Research fellow (clinical trials & epi; 2-yr) • Computational associate Join a collaborative, high-impact 🫀 precision medicine team. DM or email mhonigberg@mgb.org
💬 Invited Commentary: Flynn et al find non-DNMT3A clonal hematopoiesis of indeterminate potential (CHIP) mutations most strongly associated with heart failure risk in UK Biobank data, supporting gene-specific risk assessment. #AHA25 @ahascience.bsky.social ja.ma/4p56SeB
Non-DNMT3A clonal hematopoiesis of indeterminate potential (CHIP) subtypes—including TET2, ASXL1, JAK2, and spliceosome genes—demonstrated higher association with incident heart failure compared to DNMT3A. #AHA25 @ahascience.bsky.social ja.ma/3JQSveI
November issue now live, with Reviews on: -Clonal haematopoiesis in cardiovascular disease -Regulators of cardiomyocyte proliferation -Extracellular vesicles in cardiovascular homeostasis and disease -Factor XI inhibitors for venous and arterial thromboembolism www.nature.com/nrcardio/vol...
In this exploratory analysis, treatment with low-dose colchicine was associated with an attenuated annual clonal growth in TET2 CH. These findings suggest the potential for colchicine to curb the proliferative advantage of key CH driver mutations https://bit.ly/3HWJL5M #ESCCongress #WCCardio #JACC
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. #ESCCongress #WCCardio ja.ma/45RBaJG
New report that CHIP (clonal hematopoiesis of indeterminate potential, blood stem cell clones that increase with age) is an independent risk factor for myocarditis and pericarditis, promoting inflammation #ESC2025 @jama.com jamanetwork.com/journals/jam...
The lab's first sim pub of #ESC2025 is now online in @jaccjournals.bsky.social #JACC! jacc.org/doi/10.1016/... Led by 🇧🇪⭐️ @danielezzat.bsky.social , we examined clonal hematopoiesis (CHIP) 🩸 & CV 🫀 outcomes in older women 👵 using deep targeted 🧬 sequencing in the WHI Long Life Study 👇 (1/X)
Fantastic joint lab retreat today w/ @pnatarajanmd.bsky.social @zhiyu.bsky.social & Akl Fahed labs Honigberg lab is rapidly growing 📈 👇 @mghcvrc.bsky.social @mgbwomenheart.bsky.social @mgbresearch.bsky.social
Now accepting applications for the 2026-2027 Women's Heart Health Program Fellowship!🫀Click here for details: massgeneral.org/heart-center... @mdharringtonc.bsky.social @emilyswlau.bsky.social @mchonig.bsky.social
Women's Heart Health Fellowship Program
The Women’s Heart Health Fellowship Program at Massachusetts General Hospital provides advanced training in the prevention, diagnosis, and treatment of heart disease in women.
massgeneral.org
Registration is now open!📣We're co-hosting a patient SCAD Symposium with @scadalliance.bsky.social in October 🫀 Please click on the event page to register & for all of the details! massgeneral.org/heart-center... @emilyswlau.bsky.social @mdharringtonc.bsky.social @mchonig.bsky.social
SCAD Patient Symposium: Your Heart, Your Story
Join us October 18, 2025 for a day of building community with your peers, and hearing from renowned experts about all things SCAD.
massgeneral.org
The latest from our @americanheart.bsky.social -funded BUSY-BP study, led by MGH medicine resident Lulu Belak, now in Obstet Gynecol @greenjrnl.bsky.social In Black + Latina 👭, burden of health-related social needs in pregnancy was associated w/ adverse 🤰 outcomes journals.lww.com/greenjournal...
The inaugural MGB & Inova YIA was a huge success 🎉Please join us in congratulating 👏👏 Basic & Translational category: Winner: Maria Pabon (BWH) Honorable Mention: Amelie Vromman (BWH) Clinical Research category: Winner: Meesha Vullikanti (Yale) Honorable Mention: Izza Shahid (Houston Methodist)
Huge congrats to @massgeneralbrigham.bsky.social MGH medicine resident Amanda Jowell for receiving a top resident abstract award for her analysis of female-specific CVD risk factors in severe hypercholesterolemia 🏆 @mgbwomenheart.bsky.social @mghcvrc.bsky.social
Big congrats to Maria Pabon for winning the inaugural @mgbwomenheart.bsky.social / @ishvnews.bsky.social Young Investigators' Award (basic/translational category) for her work on endothelial cell transcriptomics in preeclampsia (www.ahajournals.org/doi/10.1161/...)! 🏆 @cardioob.bsky.social
Genetic Risk & 1st-Trimester CV Health Predict Hypertensive Disorders of Pregnancy in Nulliparous Women #CardioObstetrics #CardioSky #JACC www.jacc.org/doi/10.1016/... @mchonig.bsky.social @garimasharmamd.bsky.social @jaccjournals.bsky.social @csilvers.bsky.social @mdharringtonc.bsky.social
Our latest on 🫀 health, 🧬, and 🤰 now out in @jaccjournals.bsky.social #JACC First-trimester cardiovascular health strongly associates with development of hypertensive disorders of 🤰 (HDP) overall and across levels of HDP genetic risk www.jacc.org/doi/10.1016/... #CardioObstetrics #CardioSky
We love our team ❤️ Check out @mchonig.bsky.social's latest review!
Michael Honigberg@mchonig.bsky.social · last yr.Check out our latest review on clonal hematopoiesis🩸🧬 and cardiovascular disease 💔 now out in @natrevcardiol.bsky.social www.nature.com/articles/s41... Full text link: rdcu.be/ef9VW @mgbresearch.bsky.social @mgbwomenheart.bsky.social
Check out our latest review on clonal hematopoiesis🩸🧬 and cardiovascular disease 💔 now out in @natrevcardiol.bsky.social www.nature.com/articles/s41... Full text link: rdcu.be/ef9VW @mgbresearch.bsky.social @mgbwomenheart.bsky.social
Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target - Nature Reviews Cardiology
In this Review, Schuermans and Honigberg highlight the involvement of clonal haematopoiesis of indeterminate potential (CHIP) in cardiovascular diseases, such as atherosclerosis and heart failure, and...
nature.com
Check out our latest episode of HeartBEATS from the @americanheart.bsky.social focused on peripartum cardiomyopathy 🤰🫀 #PPCM ! @cardioob.bsky.social professional.heart.org/en/education...
Role of Cardiovascular Health in Maternal Health
Explore the role of cardiovascular health in maternal well-being. Learn warning signs, improve communication, and access life-saving tools.
professional.heart.org
Our team is gearing up for #ACC25! We'd love to see you! Come find us at one of our sessions! 🩺♥️ @mchonig.bsky.social @mdharringtonc.bsky.social @accintouch.bsky.social
www.sciencedirect.com/science/arti... #CardioObstetrics
Third-Trimester NT-proBNP for Pre-eclampsia Risk Prediction: A Comparison With sFlt-1/PlGF in a Population-Based Cohort
The association between lower first-trimester N-terminal pro B-type natriuretic peptide (NT-proBNP) levels and increased pre-eclampsia risk remains po…
sciencedirect.com
Getting ready for #ACC25? ✅ Download #ACC25 app apps.apple.com/us/app/acc-2... ✅ Follow #ACC25 ambassadors bsky.app/profile/did:... #CardioSky @accintouch.bsky.social @jaccjournals.bsky.social @saraersozlu.bsky.social @thornsberryjd.bsky.social @cathlabedu.bsky.social @bakhshihooman.bsky.social
Important trial of CAC scoring-guided CVD prevention (CAUGHT-CAD) out in @jama.com today: jamanetwork.com/journals/jam... In Australians w/ intermediate CVD risk (+ FHx) w/o clear statin indication, CAC score-guided prevention yielded reduced progression of total and non-calcified plaque over 3 y
Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease
This clinical trial evaluates the efficacy of combining coronary artery calcium scoring with a prevention strategy to limit plaque progression in intermediate-risk patients with a family history of pr...
jamanetwork.com
Danish Analysis Updates Stroke and MI Risks of Contemporary Contraceptives
Danish Analysis Updates Stroke and MI Risks of Contemporary Contraceptives
Danish Analysis Updates Stroke and MI Risks of Contemporary Contraceptives hdellabella@crf.org Mon, 03/03/2025 - 15:41 L.A. McKeown Though arterial thrombotic risk was higher with hormonal contraception use, the absolute excess risks were low.
tctmd.com
