How do our lungs heal after viral infections like flu or COVID-19? New research from @douglaspdyer.bsky.social @tracyh9494.bsky.social and Ziyun Zhang shows how the glycocalyx—a sugar layer on lung immune cells—adapts to inflammation to coordinate tissue repair. #ImmunoSky tinyurl.com/39eatz9r

How lung immune cells repair after viral infection

tinyurl.com

We can now share the peer reviewed version of our story exploring the effect of location specific queues in regulating the lung macrophage glycocalyx www.sciencedirect.com/science/arti...

Doug Dyer@douglaspdyer.bsky.social · 9mo ago

Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...

New pre-print *finally* out! We've developed ToF-SIMS for in-situ glycosaminoglycan (GAG) analysis. Here's why that matters 👇📄 (1/9) www.biorxiv.org/content/10.6...

Some useful public speaking tips from Freud here.

delighted to share our new pre-print developing label-free glycosaminoglycan analysis of diverse complex biological samples, led by @h-davies-s.bsky.social working closely with David Knight and Rebecca Miller alongisde our recent recruit Samie Dalgarno www.biorxiv.org/content/10.6...

Long-lived CD163+ and Tim4+ gut macrophages in the lamina propria are spatially restricted by TGF-β rupress.org/jem/article/... @jem.org @tovah-shaw-lab.bsky.social @edinburghuni.bsky.social @manchesterup.bsky.social

We are proud to announce the discovery of Glyco-Carbohydrates, a paradigm shift in glycobiology! Traditional glycoconjugates (proteins, lipids & RNA) max out at 50% carbohydrate. Ours are 100% carbohydrate AND glycans, unlocking truly homogenous properties. TBA April 1st, 2027! 🍬 #glycotime

Defective HLA-G1 glycosylation disrupts Siglec-7–mediated NK cell tolerance at the maternal–fetal interface in recurrent pregnancy loss link.springer.com/article/10.1...

@hepworth-lab.bsky.social new paper alert. Matt and I wrote a research highlight about recent papers that describe mechanisms of ILC2-neuron crosstalk. If you're interested in reading it, check it out! onlinelibrary.wiley.com/doi/10.1111/...

<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library

Emerging roles of ILC2 in neuronal crosstalk across organs. In a series of studies published in 2025, ILC2 were shown to regulate nervous system function across a range of organs across the body. Wit...

onlinelibrary.wiley.com

Our #JuniorPI feature for #ASMB2025 spotlights @tranejoan.bsky.social from @officialuom.bsky.social, whose work explores collagen homeostasis in fibrosis and repair🔬 She is also co‑chair of ASMB Outreach, strengthening community engagement.🎥-https://youtu.be/abjDOI39WJY @themeshwork.bsky.social

Dr. Joan Chang, Junior PI

YouTube video by ASMB - American Society for Matrix Biology

youtu.be

Organized immunity in the CNS: What stroke reveals about neuroinflammation and lymphoid niches: doi.org/10.1172/JCI2... Catalina Lee-Chang comments on Yang et al.: doi.org/10.1172/JCI1...

Interested in how age related immune dysfunction might impact stroke risk and outcomes? Check out our systematic review led by Vanda Wen Teng Ho at the National University of Singapore www.frontiersin.org/journals/agi...

Frontiers | Immunosenescence and its impact on ischemic stroke risk and outcomes in older adults: a systematic review

BackgroundAge is a major risk factor for ischemic stroke (IS), with immunosenescence–age-related immune system dysfunction - contributing to worse outcomes. ...

frontiersin.org

Long-lived resident tissue macrophages govern intraocular pressure homeostasis by regulating extracellular matrix turnover, contributing to resistance-generating tissues that are dysfunctional in glaucoma @cp-immunity.bsky.social www.cell.com/immunity/ful... @dukeeyecenter.bsky.social

Pleased to share our native glycomics workflow preserving O-acetylation, detecting this labile modification in rat (53%) and mouse (9%) serum N-glycans. Integrally, O-acetyls are invisible under standard reductive conditions. Now published at Molecular Omics. Link: academic.oup.com/molecular-om...

Native PGC-LC–MS profiling reveals distinct O-acetylation patterns of Sialylated N-glycans across mammalian sera

Abstract. O-acetylation of sialic acids represents an additional layer of structural diversity and biological complexity, occurring at various hydroxyl pos

academic.oup.com

1/ We are excited to report in @sciimmunology.bsky.social that human complete and selective LFA-1 deficiency causes isolated Epidermodysplasia Verruciformis (EV). This surprising phenotype revealed a surprising mechanism 🙂 www.science.org/doi/10.1126/...

Review @annualreviews.bsky.social @gabyrabi.bsky.social Glycan-Binding Proteins in Immunity www.annualreviews.org/content/jour...

Registration for #MBE2026 is now open! Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research. ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network! More at www.mbe2026.org

You still have 3 days to apply to the postdoc positions available in my lab 😀 🔬Come and work with us 🔬

Guillaume Jacquemet@guijacquemet.bsky.social · 7mo ago

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶

📣 2026 PhD studentship 📣 Via @manchester.ac.uk 's President's Doctoral Scholar Awards, we are encouraging applications for a PhD on the effect of pollutant exposure on microbe-immune cross talk. This project will incorporate microbiology, immunology, & bioinformatics. Deadline: 16 March 2026!

(President's Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester on FindAPhD.com

PhD Project - (President&#39;s Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester, listed on FindAPhD.c...

findaphd.com

One week left to submit your abstract for this fantastic meeting 👇 It’s gonna be a great year for matrix meetings! 😎 Fancy a full week of matrix biology? Catch a direct flight from Manchester to Frankfurt after #BSMB and join us in Heidelberg for #DGMB2026 😉

Doug Dyer@douglaspdyer.bsky.social · 6mo ago

Very excited to announce that registration is open for the BSMB Spring 2026 meeting in Manchester, April 13-14th. Already an amazing lineup and lots of opportunities to speak! Register, bsmb.ac.uk/meetings/ecm... @mcrcellmatrix.bsky.social

Reposting as one week left for early bird registration and to get your abstract in!!

Doug Dyer@douglaspdyer.bsky.social · 6mo ago

Very excited to announce that registration is open for the BSMB Spring 2026 meeting in Manchester, April 13-14th. Already an amazing lineup and lots of opportunities to speak! Register, bsmb.ac.uk/meetings/ecm... @mcrcellmatrix.bsky.social

Vaccine-induced immune thrombocytopenia and thrombosis occurs in persons with Ig light-chain allele IGLV3-21*02 or *03 that recognizes a specific epitope on the adenoviral core protein pVII, resulting in misdirection of antibody targeting PF4 @nejm.org www.nejm.org/doi/full/10....

Prof Sheena Cruickshank @sheencr.bsky.social offers insight in The Guardian @theguardian.com on the science behind sneezing and what it reveals about our health #ImmunoSky www.theguardian.com/society/2026...

The sneeze secret: how much should you worry about this explosive reflex?

It is one of the most powerful involuntary actions the human body can perform. But is a big sneeze a sign of illness, pollution or something else entirely?

theguardian.com

You still have time to apply if you are interested in joining my lab!!

Guillaume Jacquemet@guijacquemet.bsky.social · 7mo ago

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶

Been on multiple search committees For me (personally so YMMV)…I basically dismiss everything that’s labeled *submitted* unless there’s a preprint I can read

bioRxiv & medRxiv@biorxiv-medrxiv.bsky.social · 6mo ago

You can read more about that experience here: www.nature.com/articles/s41...

Very excited to announce that registration is open for the BSMB Spring 2026 meeting in Manchester, April 13-14th. Already an amazing lineup and lots of opportunities to speak! Register, bsmb.ac.uk/meetings/ecm... @mcrcellmatrix.bsky.social

Introducing the amazing Dr Lily Koumbas Foley 🥰📚👩‍🎓 @crgglasgow.bsky.social @uofgsii.bsky.social

Dr Alexander Clarke @ajclarke.bsky.social joins us from @ox.ac.uk tomorrow to give a talk entitled: “Powering the germinal centre reaction" 📆 Thursday 5th Feb 🕛 12:00 PM 📍 Michael Smith Lecture Theatre @britsocimm.bsky.social MIG Seminar #ImmunoSky

Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology. For more info 👇 sheffield.ac.uk/biosciences/...

Science update from my postdoc Peiyuan Chai - his work “glycoRNA complexed with heparan sulfate regulates VEGF-A signaling” is now published @nature.com uncovering a new layer or glycoRNA-regulation of growth factor mediated control physiological processes rdcu.be/e1bBX