Michael Seidl

@mfseidl.bsky.social

Associate Professor, Microbial Genome Evolution, Utrecht University, the Netherlands

Our new preprint is out! 🍄 Decoupled evolution of antimicrobial repertoires in lichen-forming fungi We compared many lichen-forming fungal genomes to ask how different photobiont associations relate to their antimicrobial repertoires.

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Join us and become part of PhageOrder: study the evolution of phage genetic modules!

Jessica Andreani@jessicaandreani.bsky.social · last mo.

🚨📣 Hiring a postdoc in bioinformatics 🧬🧑‍💻 Join our team at @i2bcparissaclay.bsky.social to explore biomolecular interactions and improve protein function prediction in bacteriophages! 📍 Gif-sur-Yvette, France ⏳ 13 months (+ possible extension) 📅 Apply here: emploi.cnrs.fr/Offres/CDD/U...

Finally online! It took ut 9 yars from formulating the hypothesis to actually finalizing the last experiments... but there it is!

Mélanie Rich 🌱🍄@melaniekrich.bsky.social · last mo.

New preprint alert! www.biorxiv.org/content/10.6... The conclusion of a long-lasting obsession about lipids, plant terrestrialization and the origin of plant symbioses 1/7 🧵 @pierremarcdelaux.bsky.social @katharinamel1.bsky.social @tatiana-vernie.bsky.social @kellerjeanphd.bsky.social

Thrilled to share that I'll be starting my lab at the Swedish Museum of Natural History in Stockholm as a DDLS Fellow in November! 🧑‍🔬🧬🎉 Of course, we will be delving into all things mobile DNA & evolution, as well as developing AI approaches for biodiversity genomics #newPI #TEsky #TEworldwide

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Super proud and excited about this work, led masterfully by Peiwei Chen! A fun and fruitful collaboration with department colleagues Andy Clark & Alexei Aravin. After 30 yrs of studying transposons, this is one of the very first times I see them jump in real time in their natural host! Hurrah! 🥳

Peiwei Chen@peiwei-chen.bsky.social · 2mo ago

How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...

Excited to see our new preprint on bioRxiv! 🌱🤖 We used AI protein design (RFdiffusion + ProteinMPNN) to build brand-new sensor domains from scratch and installed them in a rice NLR immune receptor engineering recognition of a Fusarium effector FoSSP17

@yuxuan-xi.bsky.social · 2mo ago

Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...