📣 Heads up! 📣 Estradiol treatment is linked to reduced risk of cardiovascular disorders, neurodegenerative disease, and certain cancers. There’s been a shortage for over a year with no moves by the FDA to declare a shortage Please sign a Change.org to fix it! www.change.org/p/ask-the-fd...

Sign the Petition

Ask the FDA to declare an estrogen patch shortage

change.org

📣 Postdoc opportunity studying ncRNAs in the brain! Great lab in NYC - Check it out! #RNAsky

Orna Issler@ornaissler.bsky.social · 2mo ago

We're hiring! The Issler Lab (NYU Neuroscience) seeks a postdoc with expertise in hiPSC-based neuronal models to study RNA biology of mood disorders. Biofluid analysis experience (CSF, plasma) a plus. Join a collaborative team in NYC's neuroscience scene. Email: orna.issler@nyulangone.org RT

We set out to map what #RNA binds to immune receptor #MDA5 during #virus infection. Our findings were unexpected: rather than viral, it was host RNA! Excited (translate: frankly, knackered) to share our paper in @natureportfolio.nature.com Nature Immunology! 🔗 www.nature.com/articles/s41... 🧵👇

📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com

Just sat through a roundtable on AI where they opened with- “Do you think it’s a good thing or a bad thing that AI is surpassing human intelligence” and I just. Wow. My questioning of the premise was met with some weird comments that we might need “co-scientists” in the loop. “Co-scientists”??

Protein-templated DNA synthesis??

Jason Rasgon@vectorgen.bsky.social · 6mo ago

WAT www.science.org/doi/10.1126/...

Neko Case has written the lyrics AND script for stage version of Thelma & Louise.

📣Excited to announce a new pre-print from the lab 📣 Led by my student @storiesofisobel.bsky.social in collab with Hemali Phatnani @nygenome.org We discovered a novel class of TDP-43 dependent cryptic gene-TE spliced transcripts: crypTEs #TEsky #RNAsky #ALS doi.org/10.64898/2026.01.09.698641

TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues

TDP-43 is an RNA and DNA binding protein that plays major roles in regulating RNA processing. In particular, TDP-43 dysfunction leads to the accumulation of cryptic splice isoforms that result from im...

doi.org

I was featured on The Scientist as a part of their 'Postdoc Portraits' series where I spoke about my scientific career path and ongoing work on oligodendrocyte dysfunction in neurodegeneration. Check it out! www.the-scientist.com/postdoc-port...

Postdoc Portrait: Priya Prakash

This postdoc uncovers how glial dysfunction drives neurodegeneration in a rare movement disorder.

the-scientist.com

📢 SIGN & SHARE THE PETITION! 📢 New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW

Sign the Petition

Support a New York State Biomedical Institute for a Healthier, More Affordable Future

c.org

I was still faculty at CSHL when Watson’s remaining titles were stripped in 2018. Duncan Watson wrote a sad/angry email to everyone living on Bungtown road. Me included. He told us we were no longer allowed to use the too “intimate” name Jim The psychology of descendants of famous men fascinates me

I'm so excited to see this Perspective with @jasonsynaptic.bsky.social out in Neuron! About 8% of our genome is made up of the remnants of LTR-containing retroelements - here, Jason and I explore the activities of retroTEs in neurological health and disease! authors.elsevier.com/c/1lzTx3BtfH...

Of all the hot takes on Rosalind Franklin, I'm truly baffled by the argument that acknowledging harm done to women somehow removes their agency. And thus, it's more "feminist" to pretend that women were not wronged by the men who tormented and harassed them

Matthew Cobb@matthewcobb.bsky.social · 11mo ago

If you believe either that Franklin discovered the double helix, and / or Watson and Crick stole her data, ask yourself how you know this. Then take a read of this article.

VOTE! VOTE! VOTE! VOTE! VOTE!

a kermit the frog is holding a sign that says vote .

Alt: a kermit the frog is holding a sign that says vote .

media.tenor.com

Finally read the paper and it's worth the buzz. mRNA vaccines saved 20 million lives in a global pandemic and the technology is opening up new avenues for the treatment of deadly cancers. This is really one of the most impactful scientific developments of our time. www.nature.com/articles/s41...

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature

mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.

nature.com

Do you research endogenous retroviruses (ERVs) or want to learn more about them? 🧬🤔 Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️ Abstracts due 1st October! events.humanitix.com/aussierv-2025 #ERV #retrovirus

AussiERV 2025

AussiERV: Australia’s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!

events.humanitix.com

Disease prevalence in US states before & after vaccine introduction 🧪 From Edward Tufte & graphics.wsj.com/infectious-d...

Filmmaker Pamela Green is planning a movie about the late Ben Barres, transgender neuroscientist, world expert on glial cells, and an inspirational advocate for women and minorities in science. Pamela is seeking funds to finish her research and script – see fundraising trailer below.

are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social? LAST WEEK TO APPLY to be a SPiNES speaker for our next season. Details and apply here: med.nyu.edu/departments-... COME AND WOW US!

a black and white photo of a crowd of people standing and sitting in chairs .

ALT: a black and white photo of a crowd of people standing and sitting in chairs .

media.tenor.com

For ESIs dealing with grants being rescinded: if an investigator’s 1st substantial independent research award is terminated within the first 3 years of the project period (not due to scientific misconduct ) they can request the reinstatement of ESI status grants.nih.gov/news-events/...

TIL that one of the books removed from the Armed Forces Library because it "had DEI" in it is Ben Barres' autobiography. Remember that you can buy and should read this book because Ben was badass and an amazing scientist mitpress.mit.edu/978026253954...

Tomorrow, 6/24, NINDS is celebrating 75 years with a special congressional briefing spotlighting scientific advancements made possible from #NINDS over the past 75 years—from foundational discoveries in brain function to life-changing therapies for neurological diseases. #neurosociety #brainresearch

Celebrating 75 Years of Scientific Discovery and Innovation: NINDS 75th Anniversary Congressional Neuroscience Caucus Briefing & Reception

Event Timing: Tuesday, June 24, 2025 - 3:30-5:00pm ET Event Address: Longworth House Office Building Room 1539, Capitol Hill, Washington, DC Snacks and refreshments will be provided

docs.google.com

The image offers a stunning variety of objects — from bright stars ranging from blue to red in color, to nearby blue spiral galaxies, to distant red galaxy groups — demonstrating the broad range of science made possible by Rubin data ✨🔭🧪

Dear Mobile DNA Researchers, The 8th Woods Hole Mobile Genetic Elements meeting will be held Aug 28 to Aug 30, 2025, at the MBL in Woods Hole, Massachusetts. Info, registration, and abstract submission: www.eventsquid.com/event/28372 #MobileDNA #MobileGeneticElements

🧬🌽 Happy Transposon Day! 🌽🧬 Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025

We hate that this t-shirt has to exist but we love the creativity behind it. Our friend Ed created it as he works to bring about change for all battling ALS. Now please follow the alien's request and complete an ALS Clinic Survey today. bit.ly/448GkkF

*URGENT* please support NIH research and the NIH employees who are standing up for science at the risk of losing their jobs! Sign *TODAY* in support of the Bethesda Declaration. The senate appropriations committee is reviewing the NIH budget Tuesday at 10 am. SHARE widely! 🧪

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff

Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

actionnetwork.org

If you burn down a forest, you don't miss out on lumber for just that season. You have to replant all the trees, nurture them, and wait for them to grow. The science and research budget cuts happening now are wanton, senseless arson. Recovery, if it ever happens, will take generations.

Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization! Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/... Congrats to all the authors and thanks to reviewers and editor!

Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila

Hsc70-4 localizes to the cell surface of Drosophila cells, binds to exogenous dsRNA, and mediates its internalization.

science.org

Our paper describing the results of the MIROCALS trial of low-dose interleukin-2 in #ALS #MND is out in the Lancet @thelancet.bsky.social Open access Read it here: www.thelancet.com/journals/lan...

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial

With this treatment schedule, IL-2LD resulted in a non-significant reduction in mortality in the primary unadjusted analysis. However, the difference between the results of unadjusted and adjusted ana...

thelancet.com