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Nikolas Stefanidis

@nikolasstefanidis.bsky.social

PhD student working with Alexander Fletcher and the Tsakiridis lab on the computational modelling of posterior nervous system development

13 Posts60 Follower124 Folgt
Benjamin Swedlund@benswedlund.bsky.social · last wk.

Check out my first preprint highlight with @prelights.bsky.social! How cells read the room - coordinated symmetry breaking and proportional cell fate allocation in neural organoids, from Hannah T Stuart et al. Lovely story with solid back-and-forth between modelling and perturbative experiments.

Minimal essential requirements for neural tube self-organisation - preLights

How cells read the room - coordinated symmetry breaking and proportional cell fate allocation in neural organoids

prelights.biologists.com

Matt Towers@matt-towers.bsky.social · last mo.

Pleased to share our latest! We show that the chick limb can be directed to recapitulate key stages in mammalian evolution, providing a unifying model for digit patterning across amniotes. Preprint: www.biorxiv.org/content/10.6... Video summary: www.youtube.com/watch?v=fvL_...

Transforming avian to mammalian modes of digit patterning

How a conserved embryonic organiser-the Sonic hedgehog (Shh)-expressing Zone of Polarising Activity (ZPA)-generates diverse limb architectures in amniotes remains a central problem in evolutionary and...

biorxiv.org

Riding With Robots@ridingrobots.bsky.social · last mo.

From NASA Photo finish! 🏁📸 On June 14, Perseverance completed a Martian “marathon” by surpassing 26.2 miles (42.195 kilometers) of travel. The day before, NASA’s Mars Reconnaissance Orbiter snapped this view of the rover and its tracks from space.

An area west of Jezero Crater, Mars, as captured by the HiRISE instrument aboard NASA's Mars Reconnaissance Orbiter on June 13, 2026. The terrain consists of a desert landscape with small hills and fields of dunes. The car-sized Perseverance rover is visible as a small, bright, blue-green dot, circled in yellow. The rover's tracks are also visible as a thin gray line winding through the terrain. NASA/JPL-Caltech/UArizona
Nicoletta Petridou@nicolettapetridou.bsky.social · last mo.

Double preprint! 👇 Check out our latest studies on timing, heterogeneity and collective behaviour (with a fun tiny bonus on evolution!) 1. www.biorxiv.org/content/10.6... 2. arxiv.org/abs/2605.13234

Cellular timing heterogeneity regulates phase transitions in living matter

Rigidity transitions govern tissue organization in ways reminiscent of inert materials. Yet, living tissues are composed of active units with autonomous timing mechanisms, raising the question whether...

biorxiv.org

Lena Schindler@lena-schindler.bsky.social · last mo.

I am thrilled to share my PhD work with @nicolettapetridou.bsky.social @embl.org: www.biorxiv.org/cgi/content/... A fun collaboration with Bernat Corominas-Murtra, Adrián Aguirre-Tamaral, @bart-smeets.bsky.social , Jef Vanghel and Tom Belpaire! Read the story in the comments below ⤵️

Gareth Moore@garethmoore.bsky.social · 3mo ago

Over the moon to see this work from my PhD finally published in Development! Using a combination of structural biology and genetics we identify an avidity-driven mechanism of BMP signal control in the extracellular space. (1/11)

Development@dev-journal.bsky.social · 3mo ago

An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation Read this Research Article from our special issue #DevSIextracellular by @garethmoore.bsky.social, @hilaryashe.bsky.social & co from @mcf-uom.bsky.social. journals.biologists.com/dev/article/... #Drosophila

An avidity-driven model of inhibitory ternary complex formation. (B) Cartoons of the proposed avidity model of ternary complex formation and subsequent BMP gradient pattern in wild-type and mutant contexts. The thickness of the double-headed arrows indicates the strength of the interactions.