We're proud to share this important work, with contributions from NYGC scientists, Nicolas Robine, William Hooper, Tim Chu, and Jennifer Shelton. This transformative resource will help advance cancer research and accelerate scientific discovery @nicorobine.bsky.social x.com/CSHL/status/...

Cold Spring Harbor Laboratory (@CSHL) on X

The next generation of cancer research models has arrived. An international consortium led by CSHL and @NorthwellHealth has developed more than 150 organoid models representing actual patient tumors s...

x.com

Today in @cellcellpress.bsky.social Dr. Hemali Phatnani and collaborators show different forms of cognitive impairment in ALS arise from biological processes, providing a new framework for understanding the disease and developing more precise therapies. Read more: www.nygenome.org/news-events/...

New Study Reveals Distinct Biological Drivers of Cognitive Impairment in ALS - August 4, 2026

Read about New Study Reveals Distinct Biological Drivers of Cognitive Impairment in ALS at the New York Genome Center on August 4, 2026

nygenome.org

Exciting to see this NIH-funded research highlighted by NIH Director Jay Bhattacharya, MD, PhD Congratulations to Bing Ren and collaborators on this important discovery—a major step forward in understanding how brain aging may contribute to neurodegenerative disease. x.com/NIHDirector_...

Jay Bhattacharya, MD, PhD (@NIHDirector_Jay) on X

🧠New NIH-funded research has uncovered an aspect of human brain aging that reshapes our approach to age-related cognitive decline and dementia risk. This knowledge will be critical as we work toward ...

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A new @science.org study co-led by NYGC CEO & Scientific Director Dr. Bing Ren provides the first comprehensive single-cell map of gene regulation in failing human hearts, revealing new therapeutic targets for heart failure. Read more: www.nygenome.org/news-events/...

A new study published in @science.org by NYGC researchers and collaborators maps how the human hippocampus changes with age using state-of-the-art single-cell genomics. Read more: www.nygenome.org/news-events/...

New Study Revises Understanding of Brain Immune Cells During Human Aging - July 23, 2026

Read about New Study Revises Understanding of Brain Immune Cells During Human Aging at the New York Genome Center on July 23, 2026

nygenome.org

Welcome to IICD, Dr. Alba Corman! A Postdoctoral Research Scientist in the Vicković Lab at @nygenome.org, her research develops next-generation controllable CRISPR screening technologies that combine single-cell multiomics and high-content imaging to identify therapeutic targets for diseases.

Nothing brings people together like the World Cup! ⚽️ Thanks to NYGC’s HR Team and Employee Engagement Group for organizing a fun social hour filled with soccer, snacks, and great company!

Last week, NYGC hosted the 2026 MacMillan Center Annual Meeting, bringing together researchers to share the latest advances in cancer genomics, single-cell technologies, epigenetics, comp bio, and AI. The meeting concluded with a keynote from Christina Leslie, PhD @mskcancercenter.bsky.social

A new study using laboratory technology reveals the inner workings of how a type of brain tumor progresses toward greater malignancy. NYGC Core Faculty @landau.bsky.social led this research with colleagues at Harvard Medical School and Mass General Brigham. Article: www.nygenome.org/news-events/...

Cancer Evolution Study Reveals Biology of Glioma Progression - July 10, 2026

Read about Cancer Evolution Study Reveals Biology of Glioma Progression at the New York Genome Center on July 10, 2026

nygenome.org

Please join us in welcoming our 2026 summer interns! Program highlights include mentorship, lab tours, scientific seminars, career development workshops, a poster session and much more!

Exploring the future of genomics 🧬 IICD's SRP and Alliance interns toured @nygenome.org, learning about cutting-edge sequencing technologies, biomedical research, and the innovations shaping precision medicine. An inspiring day of discovery and scientific exploration. #STEM #Genomics #Research

Congratulations to NYGC Core Faculty Member, Sanja Vicković, PhD on receiving an NIH R01 grant from the National Human Genome Research Institute to develop a cost-accessible platform for spatial multi-omic profiling Read more: www.nygenome.org/news-events/...

New York Genome Center aims to lower barriers to spatial multi-omics with NIH funding - July 1, 2026

Read about New York Genome Center aims to lower barriers to spatial multi-omics with NIH funding at the New York Genome Center on July 1, 2026

nygenome.org

Reminder that the #MLCB2026 paper/abstract deadline is July 1st! Conf is Nov 16-17 @nygenome.org. Fantastic lineup of keynote speakers @drannecarpenter.bsky.social (Broad/Purdue), Ellen Zhong (Princeton), Christina Leslie (MSKCC) & Michael Brenner (Harvard). More deets at mlcb.org. Please RP!

Congratulations to NYGC's Saurav Guha, PhD, FACMG, Director of Molecular Diagnostics, on leading the new @theacmg.bsky.social Guideline on Repeat Expansion detection from NGS. Read more here: https//www.gimjour...

Detection of repeat expansion variants using next generation sequencing: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)

Short tandem repeats (STRs) are a common type of genetic variation within the human genome and are defined as DNA segments composed of tandemly repeated nucleotide motifs that are usually 2-6 base pai...

gimjournal.org

🔝 What great news! 🥇Professor @tuuliel.bsky.social (@nygenome.org, @scilifelab.se) has received the prestigious European Society of Human Genetics Award Really proud of this well-deserved recognition of a member of our Scientific Advisory Board at CNAG #ESH2026 #ESHG @eshg.bsky.social

Congratulations to @landau.bsky.social, New York Genome Center Core Faculty Member, a 2026 Recipient of a Lotus Award from the Pershing Square Foundation www.nygenome.org/news-events/...

New York Genome Center Core Faculty Member, Dr. Dan Landau, Receives Award for Research on New Ovarian Cancer Targets - June 16, 2026

Read about New York Genome Center Core Faculty Member, Dr. Dan Landau, Receives Award for Research on New Ovarian Cancer Targets at the New York Genome Center on June 16, 2026

nygenome.org

Starting now: @nygenome.org ‘s Satija Lab Single Cell Genomics Day! No better annual summation of advances in single cell and spatial genomics is available, and it’s free! Don’t miss it! www.youtube.com/live/ynO1PtN...

Single Cell Genomics Day 2026

YouTube video by Satija Lab

youtube.com

Congratulations @landau.bsky.social, breakthrough technology from the lab, now live in @cellcellpress.bsky.social Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

Dan Landau@landau.bsky.social · 2mo ago

Check out full text here: www.cell.com/cell/fulltex... Congrats to Wei-Yu, Sang-Ho @ivanraimondi.bsky.social and the whole team! Gratitude to @themarkfdn.bsky.social @cegs-ica.bsky.social @smahtnetwrk.bsky.social

Join us for the 3rd NYC Chromatin Club Symposium on July 21! Registration is completely free, but be sure to secure your spot before the deadline this Friday, June 5th. To register, please use this link. docs.google.com/forms/d/e/1F...

@nevillesanjana.bsky.social Core Faculty Member of the New York Genome Center, explains how scalable CRISPR screens + single-cell sequencing are helping connect noncoding variants to disease biology and therapeutic targets. Read more; www.nygenome.org/news-events/...

Turning GWAS signals into drug targets with scalable CRISPR - May 26, 2026

Read about Turning GWAS signals into drug targets with scalable CRISPR at the New York Genome Center on May 26, 2026

nygenome.org

⚠️Preprint alert⚠️: we set up Polyethnic-1000 at @nygenome.org to study the molecular basis of cancer disparities. One striking example is endometrial cancer, with much higher mortality in patients of African ancestry.

bioRxivpreprint@biorxivpreprint.bsky.social · 3mo ago

Comprehensive Molecular Characterization of High-Grade Endometrial Cancer in an Ancestrally-Diverse Cohort https://www.biorxiv.org/content/10.64898/2026.05.01.721962v1

Researchers at the New York Genome Center have developed Lancet2, a faster and more accurate computational tool for detecting complex genetic variants across the genome. Read More: www.nygenome.org/news-events/... #Genomics #ComputationalBiology #PrecisionMedicine

NYGC Researchers Develop Lancet2, a Faster and More Accurate Tool for Detecting Complex Genetic Variants - April 7, 2026

Read about NYGC Researchers Develop Lancet2, a Faster and More Accurate Tool for Detecting Complex Genetic Variants at the New York Genome Center on April 7, 2026

nygenome.org

@nygenome.org is hiring Genomic AI Fellows! (fancy postdoc positions) If you're interested in working at the interface of AI and genomics in a great environment please apply at: jobs.silkroad.com/NYGenome/Car...

Congratulations to @tuuliel.bsky.social PhD, Senior Associate Faculty Member at the New York Genome Center, on receiving a prestigious award from the @eshg.bsky.social! Read more about this well-deserved recognition: www.nygenome.org/news-events/...

Tuuli Lappalainen, PhD Receives Prestigious European Society of Human Genetics Award - March 25, 2026

Read about Tuuli Lappalainen, PhD Receives Prestigious European Society of Human Genetics Award at the New York Genome Center on March 25, 2026

nygenome.org

Envision the future of #SpatialTranscriptomics and #DigitalPathology tools in a new article spotlighting IICD Core Member Sanja Vicković and her lab> bit.ly/40o5jOA #CancerResearch #BiomedicalEngineering #Multiomics #ColorectalCancer

Posting my talk tomorrow @nygenome.org (hosted by @gamzeandgursoy.bsky.social). lectures.gersteinlab.org/summary/AI-A... Doing genomics with AI & then seeing if AI can take over the whole thing (spoiler: not yet!). New slides on assessing agent models with externalized reasoning (vs. baselines)

@landau.bsky.social @rdrapkin8-penn.bsky.social Paul Mischel, and Adam Widman are searching for pre-cancerous signals of ovarian cancer in the blood, laying the foundation for non-invasive screening test. 🩸@tinaswish.bsky.social @weillcornell.bsky.social @mskcancercenter.bsky.social

TDP43 dysfunction in ALS leads to transposon mayhem in the transcriptome. Nice work from @nygenome.org ‘s ALS consortium, lead by Hemali Phatnani, and @nyulangone.bsky.social ‘s @karthiknatarajan.bsky.social & @mollygale.bsky.social. Nice work guys! www.biorxiv.org/content/10.6...

📣Excited to announce a new pre-print from the lab 📣 Led by my student @storiesofisobel.bsky.social in collab with Hemali Phatnani @nygenome.org We discovered a novel class of TDP-43 dependent cryptic gene-TE spliced transcripts: crypTEs #TEsky #RNAsky #ALS doi.org/10.64898/2026.01.09.698641

TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues

TDP-43 is an RNA and DNA binding protein that plays major roles in regulating RNA processing. In particular, TDP-43 dysfunction leads to the accumulation of cryptic splice isoforms that result from im...

doi.org

Now online in Cancer Discovery @aacrjournals.bsky.social: Genotype-to-Phenotype Mapping of Somatic Clonal Mosaicism via Single-Cell Co-Capture of DNA Mutations & mRNA Transcripts by @dennisjyuan.bsky.social, @landau.bsky.social, et al. doi.org/10.1158/2159... @nygenome.org @weillcornell.bsky.social