Wow - big news indeed! #zoliflodacin for #gonorrhea was just approved by the Thai FDA! I'm very curious to follow its availability, cost, and use, in which patients and which settings? And, with anything related to gonorrhea, to follow #AMR. #STIsky #IDsky

Global Antibiotic R&D Partnership (GARDP)@gardp.bsky.social · last wk.

🚨 This is BIG! The Thai FDA has approved NUZOLVENCE® (zoliflodacin), a first-in-class oral antibiotic for the treatment of uncomplicated urogenital gonorrhoea, just 6 months after its initial approval by the US FDA. 🔗 gardp.org/thai-fda-app...

Inquiring minds want to know: "How did human excrement get into our food?" It's going to take a lot of investigating at the source(s): in the fields where these vegetables are produced. #cyclosporiasis #parasites #foodsafety #farmworkers #IDSky #EpiSky

Cyclospora Spreads Through Human Feces. How Did It Get Into Our Food Supply? (Gift Article)

The large number of cases suggests that excrement entered the food system on a “surprising scale.”

nytimes.com

A great essay on maintaining our humanism in medicine. Definitely worth a read! By the one and only @nottheogdrv.bsky.social Mixed Nuts, Unsalted academic.oup.com/cid/article/...

Mixed Nuts, Unsalted

I reach inside the orange plastic bag and grab a fistful of unsalted mixed nuts. I draw a particular comfort from the sweet buttery cashews. I tolerate the

academic.oup.com

Really interesting real-world data on viral suppression among people living with #HIV initiating Cab/RPV. #HIVsky #IDsky

Clinical Infectious Diseases@cidjournal.bsky.social · 4w ago

Virologic Outcomes After LA ART Initiation with and without Viremia in Two Large U.S. Clinic Cohorts ✅ Just Accepted 🔗 https://bit.ly/4aJRdwo

As #AMR in #gonorrhea continues to rise, we were hopeful the #menB vaccine trials might show some efficacy to support the observational data. Still curious to see #MAGI trial results, hopefully soon! There still might be some promising gonorrhea-specific vaccines on the horizon🌅🙏🏽

Gabriele Pollara@gpollara.bsky.social · 4w ago

Disappointing data on meningitis vaccine preventing Neisseria gonorrhoea infections Then again negative trial data is as useful as positive findings, so that we focus resources most effectively #IDSky www.nejm.org/doi/full/10....

New in @cmijournal.bsky.social: "Which trial do we need? Evaluating plasma microbial cell-free DNA in blood culture-negative infective endocarditis" #IDSky @absteward.bsky.social www.clinicalmicrobiologyandinfection.org/article/S119...

Important article in #EID highlighting major gaps in global surveillance of #AMR in N. gonorrhoeae The authors collated genomic data for 212 isolates w/ #penA60, a key allele carrying ceftriaxone resistance, and found 48% were detected in UK and Aus. 🧐🧐 #gonorrhea #STISky doi.org/10.3201/eid3...

Limitations of Global Surveillance for <em>Neisseria gonorrhoeae</em> Antimicrobial Resistance

<em>Neisseria gonorrhoeae</em> Antimicrobial Resistance

doi.org

Sexually transmitted infections are reaching record highs in Europe New surveillance data show cases of gonorrhea, syphilis, and congenital syphilis have reached their highest levels in over a decade. Read more: ow.ly/wSBN50Z2Va4

First #hantavirus, now #Ebola. Two outbreaks in weeks are a reminder that infectious diseases are a constant global threat & the world is still underprepared. These outbreaks highlight why investment in preparedness and organizations like @who.int matters www.statnews.com/2026/05/15/e...

First hantavirus, now Ebola: What two outbreaks reveal about global preparedness

“Preparedness is not built during a crisis press conference or after a pathogen has already crossed borders,” writes Krutika Kuppalli.

statnews.com

The WHO launched a survey to understand preferences, acceptability, feasibility, and equity to help inform upcoming #gonorrhea treatment guidelines Please consider doing the survey and pass it along! 🙏🏽 Very important for community members too! #STIsky #IDsky www.who.int/news-room/ar...

Our full paper on this was just published and provides add'l insight into #HIV & #syphilis co-testing among patients receiving CT/NG testing in the #ED • Complete STI testing was low (<12%) • Disparities by race/ethnicity and sex • Co-testing 📈 over time #EMsky #IDsky 🔗 doi.org/10.5811/west...

HIV and Syphilis Testing Among Patients Tested for Gonorrhea and Chlamydia in Emergency Departments

Author(s): Sherwood, Kyla; Zhang, Neil; David, Hollie; Dekker, Annette; Garner, Omai; Samuels, Elizabeth; Adamson, Paul | Abstract: Introduction: Sexually transmitted infections (STIs), including HIV ...

doi.org

Missed Opportunities for HIV and Syphilis Co-Testing in Emergency Departments ✅ Just Accepted 🔗 https://bit.ly/4dif5sN

Testing for #HIV in Emergency Departments is so important Thought this was a great paper describing a multimodal approach, incl EHR alerts, that increased HIV co-testing with #chlamydia & #gonorrhea testing in the ED - with 5 new HIV diagnoses made 🔗 doi.org/10.1093/cid/... #IDsky #MedSky #EMsky

Increasing HIV Testing During Gonorrhea and Chlamydia Evaluations in Urgent Care and Emergency Departments: A Large Health System Initiative

A diagnostic stewardship intervention increased HIV co-testing in patients being tested for gonorrhea/chlamydia in urgent care and emergency departments. N

academic.oup.com

The #WHO just released recommendation of #doxyPEP for #STI prevention among MSM and transgender women Monitoring of #AMR also recommended Research gaps still remain, including long-term impacts on AMR/microbiome and effectiveness in different settings www.who.int/teams/global... #STIsky

Wow - very interesting case of a cerebral syphilitic gumma. Great to see such a rapid response to #penicillin. CNS infections are so often hard to diagnose, but the results can be profound. #Syphilis never ceases to amaze! #IDsky #STIsky #MedSky @nejm.org www.nejm.org/doi/full/10....

Cerebral Syphilitic Gumma | NEJM

A 50-year-old man presented to the ED with a 1-month history of headache and worsening weakness of the left arm and leg. Brain MRI showed an enhancing lesion with extensive surrounding edema.

nejm.org

All currently approved antibiotics inhibit essential cellular processes. Ever wonder if we could kill bacteria using the opposite strategy? Here, we demonstrate an alternative antibacterial strategy: lethality through pathway over-activation. www.nature.com/articles/s41... (1 out of 3)

Antifungal susceptibility testing across fungi: why MICs vary, methods diverge, and what MIC can miss Cornelia Lass-Flörl and colleagues Open access in @cmijournal.bsky.social www.clinicalmicrobiologyandinfection.org/article/S119... #IDSky #MedMycoSky

Antifungal susceptibility testing across fungi: why MICs vary, methods diverge, and what MIC can miss

Antifungal susceptibility testing (AFST) is central to antifungal stewardship; however, MIC results can be variable and may require careful interpretation because endpoints can be ambiguous, clinical ...

clinicalmicrobiologyandinfection.org

As (also) a palliative care doc, this message hit home with me: “Antibiotics may be beneficial in some cases and should not be denied to patients enrolled in hospice care.” Sometimes treating active infection improves sxs and is aligned with hospice goals. academic.oup.com/cid/advance-... #IDSky

Antibiotics in Hospice: Applying the Four-Quadrant Approach to Improve Patient-Centered Care

Abstract. The use of antibiotics in the hospice setting is complicated by differing patient goals, elevated side effects, and limited information regarding

academic.oup.com

Kaposi Sarcoma–Associated Herpesvirus Infection and Complications Among Solid Organ Transplant Recipients — United States, January 2021–September 2025 New in MMWR -46 cases of susp donor-derived KS in SOT, vs 9 from 2016–2020 -2/3 donors had a hx of nonmedical drug use www.cdc.gov/mmwr/volumes...

Exciting research here on the development and lab evaluation of #CRISPR #POC tests for #STIs (chlamydia, gonorrhea, syphilis, HSV 1 /2) Also very interesting they could detect S91F to predict cipro resistance in #gonorrhea POC tests for STIs can be game-changers in many settings #STIsky #IDsky

The Lancet Microbe@lancetmicrobe.bsky.social · 5mo ago

New research article CRISPR-Cas-based diagnostics for point-of-care detection of sexually transmitted infections: a laboratory development and evaluation study www.thelancet.com/journals/lan... #IDSky #ClinMicro #STI #OpenAccess #OA

My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com... What were your top 10? Any thoughts about what I missed welcome! #IDSky #Top10papers

A doozy of a quote in this profile of the "godfather of vaccines" by @helenbranswell.bsky.social, as he watches his field trend in the wrong direction “All I can say is that I’m beginning to regret having lived so long — because we’re going downhill,” www.statnews.com/2026/03/02/s...

A titan of vaccine development sees his field’s achievements slip away

Stanley Plotkin, the 93-year-old "godfather of vaccines," is watching his field’s achievements slip away.

statnews.com

New PJI study in @ofidjournal.bsky.social: Largest restrospective study to date of doxycycline use for PJI treatment with encouraging results All doxycycline use was in combination though, primarily rifampin. Limited to Staph, Coryne, & Cuti #IDSky #OrthoID academic.oup.com/ofid/advance...

Effectiveness of Doxycycline in Combination with Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: a Causal Inference Study

AbstractObjectives. Doxycycline is occasionally used as step-down therapy in periprosthetic joint infections (PJI), but evidence supporting its efficacy is

academic.oup.com

We are still accepting applications for our #TID fellowship/advanced training year at UCLA for 2026-27 ☀️ 🌴 - please reach out w any questions about this opportunity! recruit.apo.ucla.edu/JPF10380 #MedEd #IDSky @txidfellows.bsky.social @ast-idcop.bsky.social @idsainfo.bsky.social @idjclub.bsky.social

Transplant Infectious Diseases Career Development Position 2026-2027

University of California, Los Angeles is hiring. Apply now!

recruit.apo.ucla.edu

Good overview of an increasingly rapid-evolving field, including newly updated guidelines, non-antibiotic treatments and focus on quality of life. #UTISky academic.oup.com/cid/advance-...

Uncomplicated Urinary Tract Infections: From an Invisible Impact to a Visible Change in Complex Care

Uncomplicated UTIs may have high recurrence rates in subsets of patients, causing a substantial burden. Increasing antimicrobial resistance in uropathogens

academic.oup.com

WHO now recommends near point-of-care tests, tongue swabs, and sputum pooling for TB diagnosis! Big advance!! www.who.int/teams/global...

A case of liver necrosis 2/2 isavuconazole in a patient with genetic mutation leading to low CYP3A5 activity. 😳 Detectable levels 3 months after medication stopped 🤔 Authors suggest ALT/AST testing and TDM in older pts who have longer Isavu courses #IDSky academic.oup.com/ofid/advance...

Liver Necrosis in a Patient Receiving Isavuconazole: Making the Case for Therapeutic Drug Monitoring

Abstract. An 81-year-old man prescribed isavuconazole for pulmonary fungal infection developed high serum transaminases and biopsy-confirmed hepatic necros

academic.oup.com

🤨Comparative Effectiveness of 3 Benzathine Penicillin G-Based Regimens in PWH With Early Syphilis #CROI2026 credits @ hivvirology

Final results from a huge French PrEP study finds both daily and on-demand (aka 2-1-1) oral PrEP are safe and effective for HIV prevention. #CROI2026

French study confirms efficacy of on-demand PrEP

Eight years after it started, the final results of a large French study that offered a choice of daily or event-driven oral PrEP (using tenofovir disoproxil/emtricitabine) were presented at the Confer...

aidsmap.com

The #GoGoVax 🇦🇺 trial of the #menB vaccine against #gonorrhea among men observed no effectiveness. Results obviously disappointing, as we need more tools to prevent gonococcal infections, esp as #AMR rises. Some hope for #MAGI study 🙏🏽 #IDSky #STIsky #MedSky #CROI2026 www.healio.com/news/infecti...