I’m looking to hire an NIH funded postdoc to join our lab here at Davis (please RT). Ongoing areas of interest include: 1) polygenic signals of selection from time series, ARGs, GWAS, etc 2) The interpretation of GWAS, polygenic scores, & sources of confounding
Ashley Alexander
@peachypotato.bsky.social
Postdoctoral researcher University of Zurich Kümmerli Lab Microbiology, ecology, and evolution
🔔 New preprint from our lab: how does the chemical composition of infection-like environments shape how costly (or not) antibiotic resistance mutations are? We find that efflux pump regulator mutants can have a selective advantage in synthetic human urine + identify likely component driving this.
Fitness costs of antibiotic resistance mutations in rich media do not reliably predict those in infection-like environments https://www.biorxiv.org/content/10.64898/2026.09.08.750013v1
This job ad is now live! Please share or apply here: jobs.montana.edu/postings/52780 Screening of applicants begins Sept 15, 2026 #MicroSky #PhageSky #ScienceJobs
Postdoctoral Researcher - Lyme Disease Bacteriophage Biology
The Secor Lab seeks a postdoctoral researcher to investigate bacteriophage biology in the Lyme disease spirochete Borrelia burgdorferi. The successful candidate will help define how phiBB-1 controls h...
jobs.montana.edu
I’ll soon be #Hiring a postdoc to join the Secor Lab at Montana State University. This NIH-funded position will investigate phage biology in Lyme disease spirochetes. The official ad will be available soon. Please share with anyone who might be interested! #MicroSky #PhageSky 🔬🦠🧪🧫
Pls share: We have a new position for an Assistant Professor of Evolutionary Biology at UNLV. tinyurl.com/4uhpav4j
Assistant Professor in Evolutionary Biology, School of Life Sciences [R0153361]
The University of Nevada, Las Vegas (UNLV) appreciates your interest in employment. We ask that you keep in mind the following when completing your application: Once you start the application process ...
tinyurl.com
Imagine being talented and beautiful and rich and famous and still the most noteworthy thing about you is how good a person you are.
23% drop in student visas to US in 2025 57% drop from India alone catastrophic for research and learning, here and abroad www.insidehighered.com/news/global/...
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
The Library is devastated to learn of the passing of Dolly Parton, a music legend and titan of children's literacy. Her Imagination Library program has earned multiple Library Literacy Awards and, in 2018, she visited us to donate its 100 millionth book to our collection and host a story time. 🦋❤️
Our review on how microbes contribute to the 'taste of place' in wine is the current Editor's pick in Applied and Environmental Microbiology #AEM of @asm.org! 🍇🤩 Check out the latest on microbial terroir: doi.org/10.1128/aem.... #microbialterroir #microbiomes #review #MicroSky #MicrobiologyMonday
Microbial terroir in winegrowing: revisiting the role of microbial biogeography in terroir expression | Applied and Environmental Microbiology
Terroir describes the link between a product’s distinct characteristics and its geographic origin and has been a central principle in viticulture for centuries. Traditionally, terroir is understood to be influenced by both environmental and human factors, including soil characteristics, local climate, topography, viticultural practices, and regional choice of grapevine cultivar. This is reflected in regulations like protected denomination of origins (PDO), which are strictly defined over features such as distinct climatic conditions and geology, authorized cultivars, and often traditional management practices (1).
doi.org
"Bunsen burners are just vibing aseptic technique" yes. and the vibes are immaculate. the vibes are literally fire. this study changes nothing
As a component of aseptic technique, Bunsen burners do not universally decrease deposition of microbe-containing particles journals.asm.org/doi/full/10.... #jcampubs
My Department at the University of Illinois at Urbana-Champaign invites applications from entomologists with research portfolios in which INSECT BIODIVERSITY LOSS is a key element (at the assistant professor level). illinois.csod.com/ux/ats/caree...
New preprint of our work on effects of intra-strain diversity of Pseudomonas on modulating host response is out! Some variants of concern, flip the switch in host responses! www.biorxiv.org/content/10.6...
biorxiv.org
Officially recruiting postdocs at GW. If you are interested in genetic novelty, structural variation, or evo genetics please get in touch! We have data sets on mulitple organisms with large population sizes (Drosophila, Megalonaias nervosa) and species in decline (fireflies, mussels, elephants).
My first PhD student, @aanuoluwaduro.bsky.social graduated recently! Aanuoluwa is an excellent scientist and student, who has published some awesome work in @asm.org journals #msystems #iai doi.org/10.1128/msys... & doi.org/10.1128/iai..... I now want to highlight her most recent published work!
doi.org
Staphylococcus aureus strain heterogeneity modulates virulence traits associated to dual-species biofilms with Candida albicans
Staphylococcus aureus strain heterogeneity modulates virulence traits associated to dual-species biofilms with Candida albicans - PubMed
Staphylococcus aureus is a commensal Gram-positive bacterium and opportunistic pathogen that exhibits substantial variation in antimicrobial resistance and virulence traits. S. aureus is frequently co-isolated...
t.co
Hot off the presses! S. aureus populations hold a surprising amount of diversity that can be observed by selecting a handful of colonies from a clinical sample. @huiqiloo.bsky.social @vishnu-raghuram.bsky.social @timothyread.bsky.social doi.org/10.1128/spec...
Intraspecific diversity of Staphylococcus aureus populations isolated from cystic fibrosis respiratory infections | Microbiology Spectrum
When obtaining bacterial isolates from infections, it is important to consider the ecological biases introduced by methods used for collection and processing. In this study, we demonstrate how reducti...
doi.org
Reminder — UW #Microbiology has an open search for an Assistant Professor, focusing on fundamental problems in #bacteriology! If you or someone you know would be suitable, here's the ad: apply.interfolio.com/185622
A toxicology journal has retracted a 16-year-old study linking hepatitis B vaccines to autism in children following an independent statistical review that found a half-dozen concerns with the study’s methodology.
Journal retracts study linking hepatitis vaccine to autism that was included in CDC review
A toxicology journal has retracted a 16-year-old study linking hepatitis B vaccines to autism in children following an independent statistical review that found a half-dozen concerns with the study…
retractionwatch.com
In celebration of good friends and collaborators Erin Gloag @sirmicrobe.bsky.social, Dan Wozniak and @nanamikubota.bsky.social, here's a cool new study about rapid P. aeruginosa adaptation in wounds, with some hidden phage phun as bonus. journals.asm.org/doi/10.1128/...
Pseudomonas aeruginosa biofilm-deficient mutants undergo parallel evolution during chronic infection | Journal of Bacteriology
We demonstrate that in a porcine full-thickness thermal injury wound model, a Pseudomonas aeruginosa mutant deficient in biofilm formation undergoes adaptive evolution by acquiring mutations that alter the outer membrane, either type IV pili (T4P) or lipopolysaccharide (LPS) mutations, that restores the deficient biofilm phenotype. We also observe a striking degree of mutational parallelism, at both the biosynthetic pathway and gene level, indicating the strong selective pressures experienced by these pathways during chronic wound infection.
journals.asm.org
Conference season is here, and I'll be at #ASMicrobe! Come check out some of my latest results on the honey bee queen microbiome. I'd also love to chat about other ongoing projects on social bee multi-kingdom microbiomes, potential collaborations, or opportunities to join the Caesar Lab at OU : )
We submitted this proposal in January 2025 and it was finally funded! Grateful and excited to keep working to bring phage therapy out of the laboratory and into the clinic. @pghphageprogram.bsky.social www.medschool.pitt.edu/news/pitt-ce...
Pitt Center Is Part of First NIH-Funded Coordinated Research Network for Phage Therapeutics | School of Medicine | University of Pittsburgh
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded three new Centers for Accelerating Phage Therapy to Combat ESKAPE Pathogens (CAPT-CEP)—the first coordinated U.S. research...
medschool.pitt.edu
Do you love amplicon sequencing? Do you want to sequence MORE amplicons, faster and at lower cost? Check out 💘CUPID-seq💘, a highly multiplexed library design that lets you sequence hundreds of amplicon samples (16S, 18S, and more!) on a single sequencing run! (1/n) 🧵 www.biorxiv.org/content/10.6...
I was just informed that you can receive a 20% discount using the code AMCLF20 at the publisher's website.
New book "A Primer for Experimental Evolution" with coauthors Michael Rose, Margarida Matos, and Joe Graves. www.worldscientific.com/worldscibook... A compact primer for students and colleagues interested in planning and designing experiments to address questions in evolutionary biology.
GOOD NEWS! Researchers at Stanford University have developed a UNIVERSAL vaccine known as GLA-3M-052-LS+OVA, that protects against a wide range of respiratory viruses, bacteria AND even allergens. The vaccine is delivered intranasally AND provides broad protection in the lungs for several MONTHS.
Goodbye to seasonal viruses as we know them: the first universal vaccine against respiratory infections and allergies is now closer than ever
Scientists are getting closer to a universal nasal vaccine that could protect against respiratory viruses, bacteria and even allergies
ecoticias.com
This definitely forbidden gummy is in fact a moth larva of genus Olona (possibly Olona zolotuhini). It's *normal* to want to know what flavor it is, but the answer, unfortunately is "pain". Most species in this family are covered in tiny stinging spines connected to poison glands. (📷: Janice Ang)
Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
1/35 New preprint! We show that obligate multicellularity removes fundamental population genetic barriers to multicellular adaptation. Even a brief unicellular phase can dramatically constrain the evolution of beneficial multicellular traits. www.biorxiv.org/content/10.6...
Obligate multicellularity circumvents population genetic barriers to collective-level adaptation
Complex multicellularity has evolved in just five lineages (animals, plants, brown algae, red algae, and fungi) and in each case, these organisms develop clonally and are obligately multicellular. While prior work has shown that clonal development plays a critical role in the evolution of complex multicellularity, none has disentangled this from the impact of obligate vs facultative multicellular life cycles. Here we use experimental evolution with engineered snowflake yeast ( Saccharomyces cerevisiae ) to directly test how life cycle structure affects multicellular adaptation. We created isogenic strains capable of switching between unicellular and clonal multicellular phases, then evolved populations for 192 days under obligately multicellular, facultatively multicellular, and obligately unicellular regimes. Obligately multicellular populations rapidly evolved larger size, primarily driven by a whole genome duplication, in all five replicates. Facultative populations showed dramatically constrained evolution, with tetraploidy evolving in only 2/10 facultative populations despite experiments demonstrating that it is strongly beneficial across the full life cycle. Mathematical modeling reveals the mechanistic basis for this constraint: facultative life cycles create establishment barriers through two population genetic effects. Group formation dramatically reduces the number of units of selection, making beneficial multicellular mutations vulnerable to drift. This asymmetry in population size between life cycle phases also allows cell-level selection to overpower group-level selection, eliminating mutations that provide group-level benefits but carry cell-level costs. These findings demonstrate that obligate multicellularity circumvents fundamental population genetic barriers to collective-level adaptation, helping explain why complex multicellularity has evolved exclusively in obligately multicellular lineages, and suggesting similar constraints may operate in other evolutionary transitions in individuality. ### Competing Interest Statement The authors have declared no competing interest. U.S. National Science Foundation, https://ror.org/021nxhr62, DEB-1845363 Howard Hughes Medical Institute Gilliam Fellowship National Science Foundation Graduate Research Fellowship
biorxiv.org
Hey all! Happy to finally join everyone here on Bluesky, and also to share the culmination of my longest-running postdoc project, now on bioRxiv: “Apparent generalism in Pseudomonas aeruginosa is underpinned by convergent cryptic specialization.” www.biorxiv.org/content/10.6...
biorxiv.org