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Pete Dodd

@petedodd24.bsky.social

Mathematical modelling for TB, infectious diseases, epi & pop health

13 Posts2150 Follower689 Folgt
Finn McQuaid@cfmcquaid.bsky.social · 3mo ago

So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(www.sciencedirect.com/science/arti...)

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modi…

sciencedirect.com

Katherine Horton@kchorton.bsky.social · 5mo ago

Our analysis of #TB exposure and transmission patterns is now in @pnas.org. @petedodd24.bsky.social and I found a majority of TB transmission globally is attributable to contact with adult men, while contributions to transmission by age are more variable across regions. www.pnas.org/doi/10.1073/...

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Katherine Horton@kchorton.bsky.social · 10mo ago

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

Alvaro Schwalb@aschwalbc.bsky.social · 6mo ago

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study

Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

tinyurl.com

Nyasha Mafirakureva@nyashamafirakureva.bsky.social · 7mo ago

Our new paper highlights a substantial but under-recognized burden of #tuberculosis during pregnancy and postpartum with ~340,000 women affected globally in 2023. 👉 www.sciencedirect.com/science/arti... #MaternalHealth #GlobalHealth @petedodd24.bsky.social @tb-ipd.bsky.social @lancetgh.bsky.social

Global estimates of tuberculosis incidence during pregnancy and postpartum: a rapid review and modelling analysis

Despite known maternal, perinatal, and infant health risks of tuberculosis during pregnancy, global estimates of incidence remain scarce. Existing est…

sciencedirect.com

Katherine Horton@kchorton.bsky.social · 10mo ago

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

A global analysis of patterns of tuberculosis exposure and transmission

Tuberculosis (TB) is a major public health concern and the leading infectious cause of mortality globally. The disease exhibits strong prevalence patterns by age and sex, but the implications of these...

medrxiv.org

Ruth Bowness@ruthbowness.bsky.social · 10mo ago

PhD opportunity: New approaches to modelling TB transmission in low-incidence settings. Supervised by Ellen Brooks-Pollock (Bristol), me (Bath) & Rajeka Lazarus (Bristol) Apply: www.findaphd.com/phds/project... Deadline 20 Oct #PhD #Tuberculosis #Epidemiology #InfectiousDisease

New approaches for modelling tuberculosis transmission in low incidence settings at University of Bristol on FindAPhD.com

PhD Project - New approaches for modelling tuberculosis transmission in low incidence settings at University of Bristol, listed on FindAPhD.com

findaphd.com

Pete Dodd @petedodd24.bsky.social · 11mo ago

#Imperial PhD studentship on #electronicpatientrecords analysis for UK #tuberculosis policy, with Onn Min Kon, Jenni Quint, Sharon Cox at #ukhsa and me. www.findaphd.com/phds/project...

PhD Studentship in Respiratory Electronic Health Record Group: Analysing electronic health records to study pathways of care for people with tuberculosis at Imperial College London on FindAPhD.com

PhD Project - PhD Studentship in Respiratory Electronic Health Record Group: Analysing electronic health records to study pathways of care for people with tuberculosis at Imperial College London, list...

findaphd.com

Matthew Saunders@mjsaunder.bsky.social · 11mo ago

So...what would happen to the global TB epidemic if we hypothetically "eliminated" undernutrition? In this preprint, we combined estimates from our new review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(doi.org/10.1101/2025...)

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Background Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modifiable risk factors such as undernutrit...

doi.org

The Union@theunion.org · 12mo ago

The Union's TB Undernutrition working group is hosting a webinar with Dr Matthew Saunders. 📅 21 August at 2pm CET Dr Saunders (@lshtm.bsky.social‬) will share findings from a new analysis that redefines the relationship between BMI and TB incidence. 📧 To join email membership@theunion.org.

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Nyasha Mafirakureva@nyashamafirakureva.bsky.social · last yr.

Check out our new @PLOSGPH paper exploring the impact and cost-effectiveness of near point-of-care technology for diagnosing #tuberculosis in children in primary healthcare settings. Read it here: doi.org/10.1371/jour... From @petedodd24.bsky.social

Evaluating the health impact, health-system costs and cost-effectiveness of using TrueNat on stool samples compared to usual care for the diagnosis of paediatric tuberculosis in primary care settings:...

The World Health Organisation (WHO) recommends rapid molecular diagnostics to improve bacteriological confirmation of tuberculosis in children. TrueNat MTB, MTB Plus and MTB-RIF Dx assays (Molbio Diag...

doi.org

Pete Dodd @petedodd24.bsky.social · last yr.

Meeting the health needs of incarcerated people can be costly. We found that targeted #tuberculosis infection screening at 1st reception in England could be cost saving. www.sciencedirect.com/science/arti...

Cost-effectiveness of tuberculosis infection screening at first reception into English prisons: a model-based analysis

The World Health Organization recommends systematic screening for tuberculosis in incarcerated populations, which are consistently at high risk of tub…

sciencedirect.com

Pete Dodd @petedodd24.bsky.social · last yr.

WHO recommends treatment decision scoring algorithms to help diagnose child #Tuberculosis. Thx to #Unitaid, our TB-Speed team evaluated them to be very cost-effective for children with severe acute malnutrition in UGA & ZAM www.sciencedirect.com/science/arti...

Treatment decision algorithms for tuberculosis screening and diagnosis in children below 5 years hospitalised with severe acute malnutrition: a cost-effectiveness analysis

Children with severe acute malnutrition (SAM) are an important risk group for underdiagnosis and death from tuberculosis. In 2022, the World Health Or…

sciencedirect.com

Finn McQuaid@cfmcquaid.bsky.social · last yr.

In 2024, 68 million people were internally displaced by humanitarian crises, & are at increased risk of TB, the world's biggest infectious disease killer. We urgently need estimates to identify the scale of this problem & drive our response. We provide initial numbers here gh.bmj.com/content/10/3...

Thinking fast and slow: the urgency of crisis response must not lead us to overlook chronic needs such as tuberculosis

The number of people facing displacement due to humanitarian crises worldwide is increasing rapidly and is likely to continue. An average 10% year-on-year increase in the last 5 years resulted in 68.3...

gh.bmj.com

Tom Yates@tomayates.bsky.social · last yr.

NEW PAPER with @tom-parks.bsky.social and @petedodd24.bsky.social in @ofidjournal.bsky.social Our tool can estimate extent to which misallocation of person time will result in spurious or optimistic estimates of intervention effects We find benefits of IVIG in STSS have likely been exaggerated

Quantifying potential immortal time bias in observational studies in acute severe infection

We developed a tool to quantify the impact of misallocation of person time, then used it to demonstrate that published observational studies have likely ov

academic.oup.com

PetraHeitkamp@petraheitkamp.bsky.social · last yr.

Great article showing impact on Tuberculosis of funding freeze "Stopping this—literally overnight—means that these strains have the potential to spread not just abroad but here in the US." #EndTB #keepthelightson #11KEveryDay #RestoreTBFunding

CIDRAP@cidrap.bsky.social · last yr.

USAID funding freeze disrupts global tuberculosis control efforts The 90-day funding freeze, and the subsequent dismantling of USAID, has sent shockwaves throughout the community of people working on TB control. Photo: USAID/Flickr cc www.cidrap.umn.edu/t...

Hannah Rickman@hannahrickman.bsky.social · 2y ago

New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age. Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky

Sex Differences in the Risk of Mycobacterium Tuberculosis Infection: A Systematic Review and Meta-Analysis of Population-Based Immunoreactivity Surveys

Background: Tuberculosis (TB) killed 1·25 million people globally in 2023. Men have a 1·7-fold higher TB incidence than women, but it is not known to what exten

papers.ssrn.com

Pete Dodd @petedodd24.bsky.social · 2y ago

Newly out RCT data on integration of child TB services into routine care in KEN/CMR gh.bmj.com/content/9/12... #TBsky & our economic evaluation of it: gh.bmj.com/content/9/12...

Effect of integrating paediatric tuberculosis services into child healthcare services on case detection in Africa: the INPUT stepped-wedge cluster-randomised trial

Introduction Paediatric tuberculosis (TB) underdiagnosis is a critical concern. The INPUT stepped-wedge cluster-randomised trial assessed the impact of integrating child TB services into child healthc...

gh.bmj.com