University of Pittsburgh Department of Medicine

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Official account of the University of Pittsburgh’s Department of Medicine, a leader in transformative biomedical research, medical training, and clinical care. #H2P

The pathogenic contribution of PTPN11 mutations to AML has been unclear John C. Byrd & team reveal PTPN11 mutations in AML can be early events in the clonal evolution of disease development and are associated with variably differentiated myeloid cells: doi.org/10.1172/jci....

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