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MitoStarsLab

@richterlab.bsky.social

We are dedicated to improving the life of patients with mitochondrial disease by understanding the mechanisms that underlie their untreatable maladies. https://www.ncl.ac.uk/nuact/fellows/profiles/uwerichter/

4 Posts1035 Follower428 Folgt
Paris Marx@parismarx.com · last yr.

The days of Google Docs are ending; we enter the age of Docs, made by France's Interministerial Directorate for Digital Affairs and Germany's Center for Digital Sovereignty of Public Administration. We need more governments to collaborate on public software projects to achieve digital sovereignty.

France and Germany unveil Docs, a homegrown alternative to Google Docs

The Trump administration has set out to drastically reshape the relationship between the US and Europe. In response, Brussels is scrambling to adapt to this new reality,...

techspot.com

Lee Sweetlove@leesweetlove.bsky.social · last yr.

Lots of excellent advice in this piece. The core message - only through writing do you really think and order your thoughts into logical sense. Makes a case for not using AI for 1st draft because you bypass the thinking step www.nature.com/articles/s41... @naturebiotech.bsky.social #PlantScience

An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology

Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write

nature.com

Agnel Sfeir@agnelsfeir.bsky.social · last yr.

Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...

Engineering mtDNA deletions by reconstituting end joining in human mitochondria

Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of…

sciencedirect.com

Heiko Lickert@heikolickert.bsky.social · 2y ago

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism

The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

doi.org

Jonathan Friedman@labfriedman.bsky.social · 2y ago

Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!

Ewa Bomba-Warczak@ebomba.bsky.social · 2y ago

MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!

Death and Gravity@bushidosquirrel.bsky.social · 3y ago

Uber: we can't make money if we have to follow the law Google: we can't make money if we're not allowed to be a monopoly Nestle: we can't make money without using slave labor OpenAI: we can't make money if we can't steal media: should shoplifters be executed?

Anne Carpenter@drannecarpenter.bsky.social · 3y ago

I can’t even fathom how clueless a person would need to be to say this out loud. Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.

Tweet from Yann LeCun, which says “AI is not some sort of natural phenomenon that we have no control over. AI is being built by us, humans. Hence, if you’re scared of AI, what you were actually scared of are your fellow humans. You probably have doubts about the ability of institutions to do the right things with it. Why?”