Going to #SfN2026? Come to our Nanosymposium on Nov 16, WCC Rm143, 1-4PM (@qasimetal.bsky.social). We have an excellent lineup of short talks showcasing what recordings from the human brain reveal about how we navigate, learn, remember, balance reward, and make sense of language and other people.
Sameer Sheth, MD, PhD
@sameershethmd.bsky.social
Neurosurgeon and Professor at Baylor College of Medicine
In a new paper in @cp-neuron.bsky.social, we found that hippocampal neurons use related, but distinct, neural codes to represent self, others, and gaze. This structure may help the brain both distinguish perspectives and generalize across them. @benhayden.bsky.social @assiachericoni.bsky.social
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
cell.com
@bcmhouston.bsky.social recently launched the Institute for Brain Health to advance neuroscience research and translate discoveries into better treatments for patients. I’m excited about this vision for the future of brain health! Learn more: give.bcm.edu/campaign/ins...
The Grand Plan for brain & mind research is in terrific hands with the researchers at Baylor College of Medicine! From an excellent panel discussion across silos to many insightful conversations with PIs and trainees, I'm a bit blown away by what they are up to here. Impactful & exciting.
Drs. @benhayden.bsky.social @sameershethmd.bsky.social @assiachericoni.bsky.social et al reveal how hippocampal #neurons track the positions of self, others, and gaze direction. @cp-neuron.bsky.social @bcmhouston.bsky.social @bcmneurosurgery.bsky.social @bcmneurosci.bsky.social tinyurl.com/29mxnz2n
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
cell.com
New paper from the Neurosurgery Research Team at BCM! “Neural geometry in the human hippocampus enables generalization across spatial position and gaze” led by @assiachericoni.bsky.social! 🧵 www.cell.com/neuron/abstr...
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
cell.com
How does the #brain make decisions in real time? Check out the findings by A. Chericoni, B. Hayden, S. @sameershethmd.bsky.social et al. reported in @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social blogs.bcm.edu/2026/09/03/m...
Making decisions: how the human brain continuously balances competing goals in real time
Together, three brain regions enable the seamless balancing and updating of goals that allows us to navigate moment-to-moment decisions in the complex world around us.
blogs.bcm.edu
How does the #brain navigate between competing #goals? B. Hayden, @sameershethmd.bsky.social et al explain their findings in @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social #GPS #decissionMaking www.bcm.edu/news/beyond-...
Beyond yes or no: How the brain navigates between competing goals
How do we decide what to do when faced with choices? And how does the brain adapt those decisions as the world around us changes? A new study published...
bcm.edu
New paper from the BCM Neurosurgery research team! "Neural basis of compositional control" led by @assiachericoni.bsky.social and @justfineneuro.bsky.social ! 🧵 www.nature.com/articles/s41...
Neural basis of compositional control - Nature
Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating p...
nature.com
New preprint from my lab, showing that OFC CCEPs may be able to predict antidepressants effects in DBS for depression! With @srheilbronner.bsky.social, @sameershethmd.bsky.social, @nicoleprovenza.bsky.social
Stimulation-evoked orbitofrontal activity as a biomarker for DBS personalization in depression https://www.medrxiv.org/content/10.64898/2026.06.25.26356607v1
#Bilingual people appear to organize concepts in a shared neural structure when speaking different #languages. #brain @sameershethmd.bsky.social, B. Hayden, @xinyuanyan.bsky.social et al blogs.bcm.edu/2026/07/02/f... @cellpress.bsky.social @bcmhouston.bsky.social @bcmneurosurgery.bsky.social
Scientists discover how the brain represents meaning across different languages
The findings may help explain how people can effortlessly translate thoughts between languages without confusing them.
blogs.bcm.edu
For many bilingual people, switching between languages feels effortless. Now, scientists have figured out how bilingual brains accomplish this feat at the single neuron level. spkl.io/633297EUXJ Xinyuan Yan, Benjamin, Y. Hayden, @sameershethmd.bsky.social & colleagues @cp-cell.bsky.social
New lab paper ! "Shared neural geometries for bilingual semantic representations in human hippocampal neurons" led by @xinyuanyan.bsky.social. 🧵 www.sciencedirect.com/science/arti...
Shared neural geometries for bilingual semantic representations in human hippocampal neurons
The human brain has the remarkable ability to comprehend and express similar concepts in multiple languages. To understand how it does so, we examined…
sciencedirect.com
#NEWS: A team at @bcmhouston.bsky.social & #RiceUniversity, which includes #BCMNeurosurgery's @sameershethmd.bsky.social & @nicoleprovenza.bsky.social, has joined #BrainGate, a consortium of universities and academic medical centers working on creating brain-computer interface (BCI) technologies 🧠
Excited to share our team @nicoleprovenza.bsky.social and I and @bhaishahster.bsky.social will be joining the BrainGate consortium! This clinical trial focuses on developing assistive robotic technologies for individuals with paralysis to help improve quality of life www.bcm.edu/news/clinica...
Clinical Trial Seeks to Advance Intuitive Assistive Robotics for People with Paralysis
When a person loses a limb, a prosthesis often can help restore a significant degree of mobility. But when movement or communication is impaired by a neurological...
bcm.edu
“The brain has developed such amazing, sophisticated mechanisms for doing all these complex [language processing] tasks all day long, that it can do some of these things even without us being aware.” @sameershethmd.bsky.social explains more in a recent @nature.com article: tinyurl.com/2hf7jyn2
Baylor College of Medicine recognizes #research excellence with #DeBakey Awards. @bcmhouston.bsky.social S. Hartig, Z. Liu, R. Kommagani, A. Lee and @sameershethmd.bsky.social @bcmneurosurgery.bsky.social blogs.bcm.edu/2026/05/19/f...
#ICYMI: #BCMNeurosurgery's @sameershethmd.bsky.social and @benhayden.bsky.social are featured in Time, discussing their recent findings which suggest that the #brain is still capable of complex language processing, even while unconscious 🧠 Read more: tinyurl.com/mrxr753z
The Brain Processes Language Even Under Anesthesia, a New Study Finds
It’s further proof that even fairly complex neural processes are not the same as consciousness.
tinyurl.com
Baylor @bcmhouston.bsky.social, @riceuniversity.bsky.social join #BrainGateTeam to create #brainComputerInterface technologies that assist people with impaired #movement. @sameershethmd.bsky.social @nicoleprovenza.bsky.social N. Shah @neuroleigh.bsky.social M. Norton www.bcm.edu/news/clinica...
Clinical Trial Seeks to Advance Intuitive Assistive Robotics for People with Paralysis
When a person loses a limb, a prosthesis often can help restore a significant degree of mobility. But when movement or communication is impaired by a neurological...
bcm.edu
Please welcome Marie Vallens, our new PhD student in QCB at BCM! Her BS in Physics (Biomedical) from Portland State, MS in Bioinformatics (Neuroinformatics) from JHU, and prior computational clinical neurotech experience inform her work in our lab on semantic encoding in the PFC.
Welcoming BCM QCB PhD student Minye Zhou to the lab! She earned her B.S. in Bioinformatics from UC San Diego and M.S. in Computational Biology & Quantitative Genetics from Harvard. Her research focuses on how the brain integrates multimodal inputs to support natural behavior.
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
Plasticity and language in the anaesthetized human hippocampus - Nature
In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.
nature.com
The #humanBrain is capable of sophisticated #language processing while in an unconscious state from general #anesthesia. @sameershethmd.bsky.social, B Hayden et al explain their findings. @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social www.bcm.edu/news/researc...
Researchers discover advanced language processing in the unconscious human brain
Baylor College of Medicine researchers have found that the human brain is capable of sophisticated language processing while in an unconscious state from...
bcm.edu
#NEWS: Motif Neurotech, a brain-computer interface (BCI) company co-founded by @sameershethmd.bsky.social, has received FDA approval for a first-in-human study to evaluate its Motif XCS System, offering hope for individuals living with treatment-resistant depression 🧠 → tinyurl.com/2v7txufr
#NEWS: @sameershethmd.bsky.social has been named as one of this year's recipients of the prestigious @bcmhouston.bsky.social Michael E. DeBakey, M.D., Excellence in Research Award! The honor recognizes outstanding scientific contributions over the past three years. #BCMNeurosurgery
Proud to share funding for our R01 (MH137102) as part of an outstanding MPI team, alongside Jennifer Blumenthal-Barby and Parag Patil. Looking forward to advancing this important work at the intersection of neuroscience, ethics, and innovation. @bcmneurosurgery.bsky.social
Excited to be posting updates from Brown today at this INCREDIBLE symposium organized by @wael-asaad.bsky.social+, focused on therapies for the most formidable conditions: depression, OCD, severe autism, disorders of consciousness & memory.
Congratulations to this outstanding team—our project on reward sensitivity through a cross-species circadian lens has been selected for funding. @nicoleprovenza.bsky.social @bcmneurosurgery.bsky.social
Congratulations to these med students who did a research year in our BCM Neuromodulation group and matched today! Very proud of all of you!! Wishing you great success in your training! Gabriel Reyes, Anthony Allam, Zain Naqvi, Kasra Mansourian, Davin Devara, Holden Bentley.
Excited to share our latest work in Operative Neurosurgery on using a combination procedure of open resection and responsive neurostimulation (RNS) for epilepsy. journals.lww.com/onsonline/fu... @bcmneurosurgery.bsky.social