[JOB!] I'm hiring for a really exciting postdoc position. A combination of breeding experiments, conservation genomics, and student mentorship. Room/board at the @amnh.org Southwestern Research Station each summer, 40 months of support, new science building at BSU. Share broadly! ad: bit.ly/4hKaUIL

New paper from the Rosin lab in collaboration with the Hawley lab 🎉 Spearheaded by postdoc Leif Benner. We use imaging and RNA-seq to better understand apyrene meiosis. Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori. www.pnas.org/doi/10.1073/...

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.

So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms! www.biorxiv.org/content/10.1...

Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori

The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility and offspring health. However, Lepidopteran (moths and butterflies) males pr...

biorxiv.org

So important! Please contact your Republican senators, especially Sen. Susan Collins (R-ME), Sen. Shelley Moore Capito (R-WV), Sen. Bill Cassidy (R-LA), Sen. Katie Britt (R-AL), and Sen. Dave McCormick (R-PA). 🙏 amplify!

Ferric Fang, MD@fangferric.bsky.social · last yr.

As Robert Kuttner writes, the NIH will need support from Republican Senators to avoid draconian cuts to its FY2026 budget. prospect.org/politics/202...

🚨Postdoc opportunity🚨: LepEU postdoc: comparative population genomics of European scale adaptation in butterflies 2 year, full-time PD in my group, Stockholm Univ. Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct. Details: christopherwheatlab.wordpress.com

🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees Already 14,000+ public comments, deadline is Friday 📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful Speak up! shorturl.at/WKuBj

We're hiring an entomology collections manager @nhm.org ! I have nothing to do with the search, but happy to answer questions about the museum & LA! 🧪🦋🐝🐞🐜🦗🪰🪲🪳🕷️ workforcenow.adp.com/mascsr/defau...

@jeffsekelsky.bsky.social Corbin Jones, & I give huge thanks to Frank McNally, Christoph Haag, Andy Kern, Bengt Hansson, @takashiakeralab.bsky.social & @scienceleah.bsky.social for being guests in our #Meiosis, Recombination, & Evolution of Sex class at UNC. A pic from our final session w/ students

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish

Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...

biorxiv.org

I’m excited to share a new preprint from some of my work in the lab of @toddmacfarlan.bsky.social ! 😄 We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice

bioRxiv Genetics@biorxiv-genetic.bsky.social · 2y ago

Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice https://www.biorxiv.org/content/10.1101/2025.02.26.640358v1

Our (@jeffsekelsky.bsky.social Corbin Jones, & me) #Meiosis, Recombination & Evolution of Sex class @uncchapelhill.bsky.social loved talking w/ @scienceleah.bsky.social about her lab's @plos.org Genetics paper on a unique chromosome segregation mechanism in holocentric moths. doi.org/10.1371/jour...

Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...

New preprint drop! Check out work from @jimmy-ly.bsky.social et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. "Blue-tutorial" thread below. www.biorxiv.org/content/10.1...

Alternative start codon selection shapes mitochondrial function during evolution, homeostasis, and disease

Mitochondrial endosymbiosis was a pivotal event in eukaryotic evolution, requiring core proteins to adapt to function both within the mitochondria and in the host cell. Here, we systematically profile...

biorxiv.org

Iain Cheeseman@iaincheeseman.bsky.social · last yr.

Countdown to an epic new pre-print. Mitochondria are cells within our cells. They need the same core activities - replication, transcription, translation. How do cells enable these diverse activities in both compartments? We uncover an unexpected + broad strategy with ancient origins. Stay tuned!

🚨 New Paper Alert! 🚨 🐜 How did ants evolve their highly specialized queens and workers? With @adriatica.bsky.social, we reveal a key evolutionary innovation: adult control over larval feeding unlocked extreme caste dimorphism and complex societies. 🧵👇 🔗 Read in @pnas.org: doi.org/10.1073/pnas...

First mouse paper out from Elissa Lei’s lab! Congrats Dahong and all authors 🐭🐁🧬👀 “CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development” www.pnas.org/doi/10.1073/...

Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...

Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3

Author summary Accurate chromosome segregation is crucial for the proper development of all living organisms. Errors in chromosome segregation can lead to aneuploidy, characterized by an abnormal numb...

journals.plos.org

I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg! Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...

This is so cool!! Congrats @roneilllab.bsky.social and team! 🦀🧬 academic.oup.com/mbe/article/...

Genome Assembly of a Living Fossil, the Atlantic Horseshoe Crab Limulus polyphemus, Reveals Lineage-Specific Whole-Genome Duplications, Transposable Element-Based Centromeres, and a ZW Sex Chromosome ...

Abstract. Horseshoe crabs, considered living fossils with a stable morphotype spanning ∼445 million years, are evolutionarily, ecologically, and biomedical

academic.oup.com

Do you love meiosis? Have a cool story to share? Join us for the XVth British Meiosis Meeting 26-27 of March in Liverpool! docs.google.com/forms/d/e/1F... You only have till Sunday to submit an abstract for a talk! ECRs are prioritised for speaking slots so the odds are in your favour 😁 #meiosis4eva

Almost 200 people signed up already - add your name soon before we have to stop registration for this once in a life time conference! docs.google.com/forms/d/1dm8...

Woodstock 2.0 meets Night Science

June 10-13 in Prague & in the Woods of Bohemia Sign up here to receive information! What do we require for doing good and enjoyable science? François Jacob said it well: we need ‘an atmosphere of enth...

docs.google.com

Oded Rechavi@odedrechavi.bsky.social · 2y ago

IT'S HAPPENING! The Woodstock of Biology 2.0 meets Night Science @nightsciencepod.bsky.social 10-13 of June in Prague & the Woods of Bohemia... Be there or be REJECTED. #theconferencetoendallconferences

I just heard the news that R Scott Hawley, meiosis enthusiast and founding Dean of the Grad School of the Stowers Institute for Medical Research, passed away today. Such a loss for the science and education community. I will miss our zooms and his deep, deep wisdom

Feeling very lost today with the news of the passing of my undergrad advisor Scott Hawley. He had a huge impact on the field and on me personally. He was the first person to see me as a scientist and gave me the confidence to apply to grad school. I am so grateful to be a part of his legacy.

Sadly, our colleague and friend Scott Hawley passed away this morning. He was an irreplaceable presence and force for good in the meiosis an Drosophila communities and will be sorely missed.

Scientists of Bluesky - qPCR machine recs?

I was deeply disappointed by the lack of nature/science/climate/enviro on many major end-of-year book lists—so I decided to make my own! Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚 Please share: Let's make this go viral in time for Black Friday / holiday shopping!

Our #SpotlightZebrafish this week is on Dr. Abhinav Sur, a #postdoc w/ Dr. Jeff Farrell @ NICHD. His research uses single-cell transcriptomes to identify & map distinct populations across 62 stages of zebrafish embryogenesis & early larval development. (1/3)

Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬

Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape - Genome Biology

Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...

link.springer.com

2024 Mid-Atlantic Meiosis Mini-Symposium!! 🐭🪱🪰🧬🦠Co-organized with @scienceleah.bsky.social and @florpratto.bsky.social at NIH. Amazing talks from trainees and new PIs🎉 #meiosis4eva

The first Rosin lab paper is out in PLOS Genetics! Featuring two amazing post-bacs - Clio Hockens and Tricia Wang - and wrapping up my postdoc work: Chromosome segregation during spermatogenesis occurs through a center-kinetic mechanism in holocentric moths rb.gy/ts9u64

Chromosome segregation during spermatogenesis occurs through a unique center-kinetic mechanism in holocentric moth species

Author summary In order for genetic information to be accurately passed on from one generation to the next, maternal and paternal chromosome copies (homologs) must be separated from each other when ma...

rb.gy