Serge McGraw
@sergemcgraw.bsky.social
Associate prof @UMontreal. Quebec Canada. Developmental Biologist & Epigeneticist. Mouse Embryos | Embryonic & Pluripotent Stem Cells | Cortical Organoids | Omics | NeuroDev | #DoHAD #TBRS #FASD Research.
Congrats @sproullab.bsky.social et al! Nice to see this one published in the final version!!! Love the 🧵!
Duncan Sproul@sproullab.bsky.social · 4mo agoVery pleased to say that the paper version of our study examining the role of de novo DNMTs in cancer-associated hypomethylation is now out in @plos.org Genetics 🎉: doi.org/10.1371/jour... You can read more on the previous thread but here is a summary of the main updates! #epigenetics 🧵 1/9
Very pleased to say that the paper version of our study examining the role of de novo DNMTs in cancer-associated hypomethylation is now out in @plos.org Genetics 🎉: doi.org/10.1371/jour... You can read more on the previous thread but here is a summary of the main updates! #epigenetics 🧵 1/9
Duncan Sproul@sproullab.bsky.social · 2y agoNew pre-print alert 🚨 Interested in what @ikafetzo.bsky.social learned about DNA hypomethylation in cancer from investigating surprising gains DNA methylation in DNMT1 KO cells? Read all about it here: www.biorxiv.org/content/10.1... For a quick summary see this 🧵 1/8 #epigenetics
🚨 New preprint alert! DNMT1 is often elevated in cancer, but its direct impact on DNA methylation regulation has been hard to isolate in tumours full of confounding processes. Using a clean genetic system in mESCs, we asked: What does excess DNMT1 by itself do to the methylome? Let’s dive in 🧵 1/9
bioRxivpreprint@biorxivpreprint.bsky.social · 7mo agoMouse embryonic stem cells exhibit cancer-like DNA methylation landscapes upon DNMT1 overexpression https://www.biorxiv.org/content/10.64898/2026.01.26.701550v1
Now had a chance to read through this pre-print. Interesting and unexpected findings! Increasing DNMT1 expression leads to remodelling of the methylome in mouse ES cells including gains and losses 😮 🧵 1/2 #epigenetics
Serge McGraw@sergemcgraw.bsky.social · 7mo ago🚨 New preprint alert! DNMT1 is often elevated in cancer, but its direct impact on DNA methylation regulation has been hard to isolate in tumours full of confounding processes. Using a clean genetic system in mESCs, we asked: What does excess DNMT1 by itself do to the methylome? Let’s dive in 🧵 1/9
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine. faculty-einstein.icims.com/jobs/17847/a...
Albert Einstein College of Medicine | Medical Education | Biomedical Research
faculty-einstein.icims.com
🚨 New preprint alert! DNMT1 is often elevated in cancer, but its direct impact on DNA methylation regulation has been hard to isolate in tumours full of confounding processes. Using a clean genetic system in mESCs, we asked: What does excess DNMT1 by itself do to the methylome? Let’s dive in 🧵 1/9
bioRxivpreprint@biorxivpreprint.bsky.social · 7mo agoMouse embryonic stem cells exhibit cancer-like DNA methylation landscapes upon DNMT1 overexpression https://www.biorxiv.org/content/10.64898/2026.01.26.701550v1
The recruitment campaign is on! We’re seeking outstanding MSc, PhD, and Postdoctoral candidates to join @cra-chusj.bsky.social . If you’re passionate about epigenetics, development, and neurodevelopment, consider exploring the opportunities available in my lab. event.fourwaves.com/campagnerecr...
event.fourwaves.com
My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...
Queen’s Special U.S. Doctoral Recruitment Initiative | School of Graduate Studies and Postdoctoral AffairsDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown...
Queen’s University is a globally engaged, research-intensive institution dedicated to attracting and supporting exceptional PhD students who will significantly advance our research mission.
queensu.ca
EMBO is delighted to announce that this year the EMBO Gold Medal is awarded to Tanmay Bharat @tbharat-lab.bsky.social @mrclmb.bsky.social and David Bikard @dbikard.bsky.social @pasteur.fr for their remarkable contributions to the #LifeSciences. www.embo.org/press-releas... #award 🧪
EMBO Gold Medal 2025 awarded to Tanmay Bharat and David Bikard – Press releases – EMBO
Every year, EMBO awards the Gold Medal to group leaders in the early stages of their careers for their remarkable contributions to the life sciences in
embo.org
Congrats to all winners! ...but especially to own, Michelle Robb, for the Best Poster Award at #DOHaDCanada2025! Michelle presented our recent advances on Early Embryonic Alcohol Exposure ! 🏆
DOHaD Canada@dohadcanada.bsky.social · last yr.Congratulations to the 8th DOHaD Canada Annual Scientific Meeting presentation winners: Jade Gamelin Kao – Best Oral Presentation Michelle Robb – Best Poster Dana Watts – 2nd Place Poster Flore Lavoie – 3rd Place Poster Maurya Hart – 3rd Place Poster Thank you to all the participants!
Thank you, #DOHaDCanada2025, for organizing and for the invitation to present our work on Early Embryonic Prenatal Alcohol Exposure! #FASD #DOHaD #communautéFRQ
DOHaD Canada@dohadcanada.bsky.social · last yr.Thank you to everyone who attended the 8th DOHaD Canada Annual Scientific Meeting. A special thanks to our outstanding co-chairs, Dr. Tina Montreuil and Dr. Sarah Lippé, for organizing the event. Here are some highlights. #DOHaDCanada2025 #ScientificMeeting #Gratitude #EventRecap
Congratulations to our co-president, Dr. Kristin Connor (@kconnor.bsky.social), for being awarded the Nick Hales Award by the International DOHaD Society. #DOHaD2025
Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely. mcgill.wd3.myworkdayjobs.com/en-US/McGill...
Assistant Professor (Research), Department of Microbiology & Immunology, (C2-240724)
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
mcgill.wd3.myworkdayjobs.com
Paper Out👇🥳 thanks to ALL authors, Nakatani-san @tamas-schauer.bsky.social @palmrinmoy.bsky.social and bluesky-less RIF1 regulates Replication Timing in mouse embryos & (suprising) findings disentangling effects on transcription and LADs...lots to think about 🙄👍🤔 👉 www.cell.com/developmenta...
Sophie Petropoulos, chercheuse au CRCHUM, et son équipe révèlent pour la première fois que l’embryon préimplantatoire de cochon d’Inde est très similaire à l’embryon humain, ce qui ouvre la voie à une meilleure compréhension de l’infertilité et du développement humain précoce.
Le cochon d’Inde : un modèle animal prometteur pour l’étude de l’embryon humain
Sophie Petropoulos, chercheuse au CRCHUM, et son équipe révèlent pour la première fois que l’embryon préimplantatoire de cochon d’Inde est très similaire à l’embryon humain, ce qui ouvre la voie à une...
bit.ly
🥂Congratulations to Petropoulos & co for their new Open Access study in our journal (@naturecellbiology.bsky.social): single-cell #transcriptomics, spatial, functional and comparative analyses show that the guinea pig presents high similarity with early human #embryogenesis. bit.ly/3RaRwWY
The guinea pig serves as an alternative model to study human preimplantation development - Nature Cell Biology
Petropoulos and colleagues perform single-cell transcriptomics, spatial, functional and comparative analyses, and show that the guinea pig presents high similarity with early human embryogenesis.
bit.ly
The Lim Lab at the @crchum.bsky.social is recruiting PhD students or Postdoctoral Fellows to study the roles of 14-3-3zeta in #adipocytes or pancreatic #betacells. Projects are supported by CIHR, NSERC, or Diabetes Canada. Please share with people who might be interested! Thanks!
I urge folks to sign this letter and share it with their university colleagues to get critical mass.
Dylan MacKay@dylanmackayphd.bsky.social · last yr.Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share docs.google.com/document/d/1...
🔊Share widely! Were looking for a Tier 2 CRC in Human Metabolic Disease! Just posted but hurry as app deadline is May 15! Got expertise in #obesity or #diabetes and are an emerging expert in your field? Apply now!!!! carleton.ca/deputyprovos...
Assistant or Associate Professor and Canada Research Chair, Tier 2, Biology or Health Sciences or Neuroscience (Human Metabolic Disease) - Office of the Deputy Provost (Academic Operations and Plannin...
About the Position The Faculty of Science invites applications for a Canadian Institute of Health Research (CIHR) Tier 2 Canada Research Chair (CRC) appointment in Biology, as applicable to Human Meta...
carleton.ca
Dear USA colleagues, paradoxically the environment is warmer for doing science north of the border.♥️
University Health Network@uhn.ca · last yr.Today UHN launches the Canada Leads 100 Challenge! 🇨🇦💯 We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation! Learn more: www.uhn.ca/corporate/Ab...
This should save grant reviewers a lot of time on some of those proposals…..
Maxim Greenberg@maxvcg.bsky.social · last yr.This is a devastating and essential read. Here is a gift link for those without subs. The part about outside perceptions of scientists compared with almost a blue-collar reality is spot on (without even mentioning meager salaries). www.nytimes.com/2025/04/03/o...
Argonautes 2025 will cover progress in: Structural insights Effector complexes: formation, composition & function Post-transcriptional silencing Transcriptional silencing & DNA cleavage Post-translational modifications and regulations Medical aspects 27-30/8/2025 argonautes.img.cas.cz Pls RT!
For Canadian cancer researchers concerned about travelling to the US (🙋🏼♂️), please check out and plan to be at the Canadian Cancer Research Conference in Calgary this November. All welcome. www.ccra-acrc.ca/conference/
Conference - CCRA
ccra-acrc.ca
Thank you @stemcellnetwork.ca for internship scholarship to the lab to support the next generation of stem cell scientists!!
a baby is saying thank you with a serious look on his face .
ALT: a baby is saying thank you with a serious look on his face .
media.tenor.com
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
The Groth lab@grothlab.bsky.social · 2y ago🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
Come by my colleague!! Assistant professor position in molecular neurobiology at @mcgill.ca and the Lady Davis Institute! mcgill.wd3.myworkdayjobs.com/McGill_Caree... Montreal is an amazing city and the Lady Davis is a great institute to work at!
Assistant Professor (Research), Department of Anatomy and Cell Biology (C1-250306)
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
mcgill.wd3.myworkdayjobs.com
🌟 SAVE THE DATE: Talent Forum 2025! 🗓️ November 18–19 📍 @www.helmholtz-munich.de, Germany Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research! Apply by July 31 for a speaker spot —travel & accommodation covered. 🔜 Website coming soon!
