The great @becherlab.bsky.social lab introduces Adenophages: GM-CSF dependent cells with similarities to DCs in various exocrine glands. Upon pilocarpine stimulation, they trigger salivation! Now the big question: do they exist elsewhere in the body too? www.nature.com/articles/s41...
simonyona
@simonyona.bsky.social
exploring monocytes, macrophages and DC
F4/80, the Plasma Membrane Antigen of Mouse Macrophages, an historic journey academic.oup.com/jleukbio/adv...
F4/80, the Plasma Membrane Antigen of Mouse Macrophages, an historic journey
The F4/80 antigen is a plasma membrane pan-marker for resident and recruited mouse tissue macrophages.
academic.oup.com
🚨 This Thursday the biennial meeting of the French DCs society at the institut Curie in Paris will start🚨. Some last seats are available if interested... Registration and Final Program here: www.cfcd.fr/meeting/prog...
Our new collection highlights recent advances in our understanding of #macrophages & #dendriticcells, and their roles in #infection, #allergy, #cancer, #neuroinflammation, & #neurodegeneration. Read new research to accompany next week's #EMDS2025! rupress.org/jem/collecti... @emds2025.bsky.social
Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you! www.cell.com/immunity/ful...
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis
Immune-microbiota interactions are required to maintain host homeostasis. Kim et al. identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents spontaneous lung inflammat...
cell.com
Interested in cellular cross-talks between dendritic cells and T lymphocytes in lung cancer? Our team is recruiting a postdoctoral associate in immunology at Institut Pasteur Paris! research.pasteur.fr/fr/job/post-...
Post-Doctoral position in cancer immunology and immunotherapy, Institut Pasteur, Paris, France - Research
Deciphering the role of intra-tumoral dendritic cells in the dynamic controlof CD4+ and CD8+ lymphocytes in lung cancer. A 3-year, post-doctoral position is available in the Guermonprez lab at Institu...
research.pasteur.fr
If you want to lead a group doing great research in a special environment, and teach outstanding students, this could be for you Associate professor in cell/mol biology @dunnschool.bsky.social
We just can't stop recruiting! Associate professor in cell and molecular biology @dunnschool, with a preference for immunology, inflammation and/or infection - all defined broadly Come and be our colleague Deadline 28 Feb, please spread the word www.path.ox.ac.uk/vacancy/asso...
🍬Our 2024 update🍬 on monocytes their origins and development - with @kim-lab.bsky.social and Alex Mildner - The image below uses a 'sweet shop analogy' to illustrate the plasticity of monocytes during the immune response 🍬 artist Maya Rachman doi.org/10.1093/disc...
‼️ SAVE THE DATE The next EMDS Meeting will take place from 16-18th Sept. 2025 in majestic Edinburgh 🏴. If you love macs, monos &/or DCs, or just want to learn more about them, THIS is the meeting for you. Space limited - so watch out for details. @britsocimm.bsky.social
Our annual "Best of JEM" series highlights some of the most exciting studies from the last 12 months. We present you with research in basic #immunology, #immunotherapy and tumor immunology, inborn errors of immunity, #neurodegeneration, & #inflammation: https://buff.ly/4iwWcCJ
Venetia Bigley had a wonderful talk on human IRF8 mutation and human DC3 subset at day 3 of #EMDS2024
Fantastic and as always enthusiastic talk by @martinguilliams.bsky.social on CRISPR screens / cell-cell interactions within the macrophage niche
Great talk by @gastrogrj.bsky.social at #EMDS24 describing our work on itaconate as a molecular handbrake restraining monocyte function in intestinal inflammation. @edinuni-irr.bsky.social @britsocimm.bsky.social @societymucosalimm.bsky.social
Wonderful morning of talks at #EMDS2024 🤩 - including on the identification and importance of immune cell #spatial #niches in chronic inflammation - and in cancer 🧪 Andreas Schlitzer Merad Cohen @martinguilliams.bsky.social
First meeting with 🦋
What happens to monocytes when a human gets LPS induced activation? Fantastic talk from Simon Yona at the #EMDS2024 meeting in Vienna: tracking the fate of monocytes and DCs in healthy and inflamed humans! Blood and bone-marrow data in function of time 👏🏻👏🏻👏🏻
✨This month - Human dendritic cells (DC)✨ using stable isotope labelling in healthy volunteers, we define the circulating lifespan of cDC subsets and explore their role in inflammation - huge thanks to the team and our amazing collaborators doi.org/10.1084/jem....
Up next in highlights from this month's #ScienceImmunology was a Focus commentary from Alexander Mildner and Simon Yona discussing the challenges of mapping the identities of recently described #monocyte subsets with different origins and functions.
Monocytes and their doppelgängers: An immunological crossroads
Monocyte research reveals “doppelgänger” populations that resemble classical monocytes but differ in origin, function, or migration.
science.org