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Calum Bain

@bainlab.bsky.social

Scottish Immunologist based in The School of Infection & Immunity at The University of Glasgow. Honorary Fellow at The Institute for Regeneration and Repair at The University of Edinburgh.

42 Posts463 Follower210 Folgt
Calum Bain@bainlab.bsky.social · 4mo ago

Our latest preprint in an awesome collaboration with the Wack Lab @crick.ac.uk. Led by @chrysante-ili.bsky.social, @woutertj.bsky.social and @isobelmouat.bsky.social. We show that monocytes follow a largely conserved differentiation blueprint in the 🫁 when elicited by distinct challenges.

Waggoner Lab@labwaggoner.bsky.social · 5mo ago

@biorxivpreprint.bsky.social Diverse lung challenges elicit a conserved monocyte-to-macrophage differentiation blueprint @bainlab.bsky.social @crick.ac.uk @edinburghuni.bsky.social @chrysante-ili.bsky.social www.biorxiv.org/content/10.6...

Calum Bain@bainlab.bsky.social · 4mo ago

Our latest preprint in an awesome collaboration with the Wack Lab @crick.ac.uk. Led by @chrysante-ili.bsky.social, @woutertj.bsky.social and @isobelmouat.bsky.social. We show that monocytes follow a largely conserved differentiation blueprint in the 🫁 when elicited by distinct challenges.

Waggoner Lab@labwaggoner.bsky.social · 5mo ago

@biorxivpreprint.bsky.social Diverse lung challenges elicit a conserved monocyte-to-macrophage differentiation blueprint @bainlab.bsky.social @crick.ac.uk @edinburghuni.bsky.social @chrysante-ili.bsky.social www.biorxiv.org/content/10.6...

Calum Bain@bainlab.bsky.social · 5mo ago

Lovely to see the imaging by @lizihegarty.bsky.social making the front cover of @mucosalimmunol.bsky.social. Instead is our work on #macrophage heterogeneity & dynamics in health & inflammation. We also did a short podcast to discuss the main findings. @edinuni-irr.bsky.social @uofgsii.bsky.social

Mucosal Immunology@mucosalimmunol.bsky.social · 5mo ago

The February issue of MI is online now, and featuring imaging from @bainlab.bsky.social and @lizihegarty.bsky.social on the cover www.mucosalimmunology.org/issue/S1933-...

Elaine Emmerson@doctoremmerson.bsky.social · 6mo ago

Our latest preprint, led by @lizihegarty.bsky.social & aided by @erinwatson.bsky.social shows that fixation time matters when it comes to visualising #macrophages in #salivarygland & other epithelia.We find 1hr allows detection of mac subsets while preserving architecture. With @bainlab.bsky.social

bioRxiv Immunology@biorxiv-immuno.bsky.social · 6mo ago

Fixation matters: duration in fixative prior to immunofluorescent analysis directly impacts macrophage visualisation in epithelial tissues https://www.biorxiv.org/content/10.64898/2026.02.13.705745v1

Mucosal Immunology@mucosalimmunol.bsky.social · 6mo ago

This #MucosalMonday @bainlab.bsky.social and @lizihegarty.bsky.social are in the Authors Corner discussing their recent #macrophage work from MI. Then @kknoop.bsky.social brings you more allergy and anaphylaxis with Caroline Sokol and @stephanieeisen.bsky.social: www.iheart.com/podcast/269-...

Allergy at AIC, part 2 - Mucosal Immunology Podcast | iHeart

<p>This episode includes more discussions from the Autumn Immunology 2025 Conference 2025 conference. KathrynKnoop sits down with Drs.  Caroline Sokol and Stephanie Eisenbarth to discuss food and skin...

iheart.com

Calum Bain@bainlab.bsky.social · 8mo ago

Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social. Might be of interest to @emds2025.bsky.social attendees!

Mucosal Immunology@mucosalimmunol.bsky.social · 8mo ago

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair in this work from @lizihegarty.bsky.social, @bainlab.bsky.social, and colleagues: www.mucosalimmunology.org/article/S193...

Calum Bain@bainlab.bsky.social · 8mo ago

Do tissue resident #macrophages survive through intestinal #inflammation? Are they terminally differentiated or can they adapt? @lizihegarty.bsky.social asked these Qs during her @wellcometrust.bsky.social PhD and her findings are now published @mucosalimmunol.bsky.social @edinuni-irr.bsky.social

Elaine Emmerson@doctoremmerson.bsky.social · 9mo ago

Thrilled for our wonderful postdoc @lizihegarty.bsky.social whose #PhD work on colonic #macrophages and #colitis with @bainlab.bsky.social @edinuni-irr.bsky.social has been accepted for publication in @mucosalimmunol.bsky.social 🔬 www.sciencedirect.com/science/arti...

Alejandro Brenes@ajbrenes.com · 9mo ago

#Neutrophils are short lived cells, yet in ARDS display long term changes, with impaired neutrophil functions even after 6 months. How can they undergo long term reprogramming? this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky

Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity - Nature Immunology

Walmsley and colleagues report that systemic hypoxia induces persistent loss of histone H3K4me3 marks and epigenetic reprogramming in neutrophil progenitors, resulting in long-term impairment of subse...

nature.com

Calum Bain@bainlab.bsky.social · 10mo ago

Did you attend #EMDS2025? If so, please take time to tell us about your experience in the survey you received. This will help the organisers of #EMDS2026 (Amsterdam, November 2026) @edinuni-irr.bsky.social @britsocimm.bsky.social

@emds2025.bsky.social · 10mo ago

The sun has set on #EMDS2025 but be sure to complete the survey sent out last week. We need your feedback, good or bad, to ensure that future meetings reflect your priorities and address any concerns. @britsocimm.bsky.social @efis-immunology.bsky.social Photo credit: Becky Dempsey

Calum Bain@bainlab.bsky.social · 11mo ago

Well done @lizihegarty.bsky.social. You are an exemplar postdoc - hardworking, well-read, conscientious, supportive, collegiate, all while being good fun (and expert in where to dine!!). Delighted to have you as a colleague. @edinuni-irr.bsky.social @uofgsii.bsky.social @britsocimm.bsky.social

Elaine Emmerson@doctoremmerson.bsky.social · 11mo ago

Absolutely delighted that our superstar #postdoc @lizihegarty.bsky.social was awarded the @cmvm-edinburghuni.bsky.social Student Support & Supervision Award for #PAW 2025. Thoroughly deserved for everything she does for @emmersonlab-irr.bsky.social, @bainlab.bsky.social & @edinuni-irr.bsky.social

Elaine Emmerson@doctoremmerson.bsky.social · 11mo ago

Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.

bioRxiv Immunology@biorxiv-immuno.bsky.social · 11mo ago

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1

Calum Bain@bainlab.bsky.social · 11mo ago

Delighted all of @lizihegarty.bsky.social's hard work as paid off. She shows that tissue resident colonic #macrophages persist through #inflammation and adapt to aid tissue repair. Lovely collaborative work with colleagues @edinuni-irr.bsky.social and beyond. 🙏🏻 @uofgsii.bsky.social

bioRxiv Immunology@biorxiv-immuno.bsky.social · 11mo ago

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1

Calum Bain@bainlab.bsky.social · 11mo ago

Amazing! Well done @lizihegarty.bsky.social. Thoroughly deserved. You contribute so much to the Emmerson and Bain labs. @edinuni-irr.bsky.social @uofgsii.bsky.social

Elaine Emmerson@doctoremmerson.bsky.social · 11mo ago

Absolutely delighted that our superstar #postdoc @lizihegarty.bsky.social was awarded the @cmvm-edinburghuni.bsky.social Student Support & Supervision Award for #PAW 2025. Thoroughly deserved for everything she does for @emmersonlab-irr.bsky.social, @bainlab.bsky.social & @edinuni-irr.bsky.social

Doug Dyer@douglaspdyer.bsky.social · 11mo ago

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road

Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:

jobs.manchester.ac.uk

@emds2025.bsky.social · 11mo ago

📣 Journal Editors at EMDS2025:Scotland Edition @gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells @efis-immunology.bsky.social

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Journal of Experimental Medicine@jem.org · 11mo ago

Our new collection highlights recent advances in our understanding of #macrophages & #dendriticcells, and their roles in #infection, #allergy, #cancer, #neuroinflammation, & #neurodegeneration. Read new research to accompany next week's #EMDS2025! rupress.org/jem/collecti... @emds2025.bsky.social

Matthew Freeman@mjafreeman.bsky.social · 11mo ago

Another exciting opportunity @dunnschool.bsky.social ! Come and be a colleague to a great group of scientists working on the fundamental mechanisms underlying disease, and how to transform health Please help us find great applicants

The Dunn School, Oxford@dunnschool.bsky.social · 11mo ago

We're hiring (again)! We are looking for an associate professor in cell and molecular biology, with a particular focus on immunology (defined broadly) If you have a great record and exciting plans, consider joining our thriving and welcoming department www.path.ox.ac.uk/vacancy/asso...

Calum Bain@bainlab.bsky.social · 11mo ago

Still time to register for #EMDS2025 in the wonderful city of Edinburgh! All details including invited & selected speakers and their abstract details at www.emds2025.com Plus, the chance to take part in a traditional ceilidh!

a blue and white flag with an x on it

ALT: a blue and white flag with an x on it

media.tenor.com

@emds2025.bsky.social · 11mo ago

Speaker Highlight - Barbara Schraml What controls functional programming of #dendritic cells? Join us at #EMDS2025 to hear from @barbaraschraml.bsky.social about their recent work on DC diversity. www.emds2025.com @britsocimm.bsky.social @efis-immunology.bsky.social [Background photo: Yao Fu]