Watching an old (stupid) movie- its weird how much John Larroquette and David Williams look alike - if it wasn’t for the 25 years I would’ve thought they were the same person

Another Oxford cargo bike theft!! Mine is customised by having a lot of stickers and nail varnish my kids did on it. Stolen on Meadow Lane at 18.30 today locked to a Sheffield stand. Please LMK if anyone sees it for sale. Probably in Cambridge. ;)

I wish Calgary would embrace other themed costume weeks like it does Stampede. There should be a week where we dress up like magicians. Another where everyone is now a zebra. It would be good.

I'm not sure I've ever seen a single sentence go downhill this far and this fast

The Guardian@theguardian.com · 2mo ago

Therapy ferrets used to kill rats at UK’s largest children’s prison

“Putting a perfect GPA in reach of so many students perversely deters them from taking classes that could threaten it,” Harvard professor Joshua Greene argues. “We should liberate our students from the tyranny of the impeccable transcript”:

Harvard Needs a Cap on A Grades

“Putting a perfect GPA in reach of so many students perversely deters them from taking classes that could threaten it,” Joshua Greene writes. “We should liberate our students from the tyranny of the impeccable transcript”:

bit.ly

For more than a decade, a seventh-grade math teacher used technology in his classroom. This year, he took the Chromebooks away—and quickly learned how the computers were holding his students back, Jenny Anderson writes.

What Happened After a Teacher Ditched Screens

Why one early adopter of computers in classrooms has decided to toss them.

bit.ly

AI detection systems - its AI, why would anyone concerned about AI trust these?

Jason Sanford@jasonsanford.bsky.social · 4mo ago

I agree 100% with Steven Vickers that authors will be falsely accused of using AI in the coming years. In particular, authors like myself whose works were stolen to train AI systems are at risk. When we write in our own unique styles, AI trained on us will quite likely flag us as using AI.

www.organic-chemistry.org/abstracts/li... A Rh-catalyzed asymmetric reductive Heck reaction of aryl, heteroaryl, or vinyl boronic acids and phenyl pyridine-1(2H)-carboxylate provides 3-substituted tetrahydropyridines

We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

I can't be the only one who is made /uncomfortable/ by the way that razor clams burrow into sand, right? The final moments of this video by Kate Crump on the Oregon coastline are sort of the crowning glory of horror. 😬 But how does this even work? Let's talk about bivalve mobility (if we must).

Congratulations to the prize-winners from our recent Early Career Researcher Symposium and Poster Event in Organic Chemistry & Chemical Biology, sponsored by Pharmaron. Pictured are poster prize winners Stanley Oppong, Oskar Ford, Sara Borghi, Nandini Guzman and Maddison Lovell.

Banbury gets this, and we get.. more lab space. CITY CENTRE PLAYGROUND WHEN, @oxfordcitycouncil.bsky.social ?! Maybe we should #bemoreBanbury Bit of imagination?!

Oxford Clarion@oxfordclarion.bsky.social · 6mo ago

The site of Debenhams in Banbury’s Castle Quay is to be transformed into a 50,000 square foot multi zone indoor playground for all ages including a ninja style assault course, slide city and a soft play for children. It is set to open in Summer 2026. castlequay.co.uk/whats-on/fun...

Without naming your job, tell me something you say over and over again at work. What does the TLC look like?

Matt Hartings@matthartings.bsky.social · 6mo ago

Without naming your job, tell me something you say over and over again at work. Is it sterics or electronics??? Why not both?!?!

A colleague asked me if anyone can identify this glassblowing tool. From the collection of a distinguished long gone colleague. Happy to hear thoughts.

organic chemistry IV art history the new German film society and freedom contemporary myths

Chemjobber@chemjobber.bsky.social · 6mo ago

Tell me five classes you took in college. Molecular Biology of HIV History of the Civil War Organic Chemistry (2.5X, lol) Science Writing Physical Chemistry (woof)

Activity-based protein profiling covalent small molecules that potentiate the activity of the METTL5:TRMT112 complex through binding to a complexoform-restricted allosteric pocket absent in other TRMT112:methyltransferase complexes www.nature.com/articles/s41...

We're Hiring! If you are interested in a PDRA post with the Mehta group, please apply! @ox.ac.uk @oxfordchemistry.bsky.social my.corehr.com/pls/uoxrecru...

In @science.org for chemsky this week, Michael Willis’ group make beta-lactam analogues with S=O in place of C=O, using energy-transfer reactivity of N-silyl sulfinylamine precursors. www.science.org/doi/10.1126/...

Access to four-membered cyclic sulfinamides by energy transfer catalysis

Synthetic transformations that advance through excited states proceed by unconventional mechanistic pathways and deliver products not accessible using ground-state chemistry. The breadth of these synt...

science.org

Two (2) corkscrews went down trying to open this

Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.

Come be my colleague @ucdchemistry.bsky.social! We're currently looking for an organic chemist (broadly defined) to start as a permanent (i.e., tenured) assistant professor. Job reference (www.ucd.ie/workatucd/jo...) is 019237. Due date Feb. 27, 2026 Reach out if you have questions!

Beep was nasty…

Canadian History Ehx@cdnhistoryehx.bsky.social · 8mo ago

For five decades, Beep Fruit Drink was a lunchbox staple for many. Created and manufactured in Nova Scotia, the drink was very popular. Eventually though, sales started to decline leading to its discontinuation (TWICE!). This is the story of Beep Juice! 🧵 1/5

On Dec. 6, 1917 at 8:45 a.m., the Imo and Mont-Blanc (which was packed with explosives) collided in Halifax Harbour. At 9:05 a.m., the Mont-Blanc exploded. The 2.9 kiloton blast levelled most of Halifax, killed 1,700 and injured 9,000. This is the story. 📸 LAC 🧵 1/12

watching The wire - Omar easily one of the best bad guys ever

A movie that takes place where I’m from

a hockey player wearing a blue jersey with the letter a on the front

ALT: a hockey player wearing a blue jersey with the letter a on the front

media.tenor.com

The chemotypes within FDA approvals so far this year are quite diverse. Most of the 2025 small molecule approvals are chiral with four covalent electrophiles.

any suggestions for a equivalent reagent for Na/Hg?