Interface paper is now published www.mdpi.com/2075-4426/15...

GOOD NEWS! Researchers have found that getting vaccinated against shingles- a painful and debilitating condition that can flare up years after infection from VZV- not only LOWERS the risk of infection, but can also PROTECT against dementia and REDUCE the risk of cardiovascular disease! 🧪🧵⬇️

did you think that labetalol is a single drug? nope it’s actually a mixture of FOUR different drugs RS, RR, SS, and SR-labetalol and this is clinically relevant! lets discuss why… 🧵 #1/3 #EMIMCC

For many experts, Health. Secretary Kennedy’s promise to find autism’s causes in a few months is jarring — and unrealistic. That’s because it appears to ignore decades of science linking about 200 genes that play a role. apnews.com/article/auti...

Experts call Kennedy's plan to find autism's cause unrealistic

Many autism experts say the Trump administration's plan to find autism's causes is unrealistic. Health Secretary Robert F.

apnews.com

tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superior

Vinay Prasad, in his own words, outlines the philosophy he’ll bring to the FDA

Vinay Prasad, tapped to be a top official at the FDA, has never shied from speaking his mind.

statnews.com

Texas measles total tops 700 cases amid rises in other states www.cidrap.umn.edu/measles/texa...

Texas measles total tops 700 cases amid rises in other states

Also, health departments in Illinois, North Dakota, and Missouri reported more measles cases.

cidrap.umn.edu

20 years after it was approved, cardiologists are recognizing that ezetimibe is a great statin helper www.msn.com/en-us/health/other/cardiologists-say-statin-combination-therapy-can-reduce-cholesterol-related-deaths-by-49/ar-AA1CKN9r?ocid=msedgntp&pc=DCTS&cvid=77de09834e2542b09bdbdbf88b12fbac&ei=11

Most vaccines don’t trigger mucosal IgA—a key airway defense Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2 www.nature.com/articles/s41...

www.voicesforvaccines.org/jtf_topics/d...

Do vaccines contain aborted fetuses?

Do vaccines contain aborted fetuses? No—some use decades-old fetal cell lines for development, but no new cells are used. Learn the facts behind this persistent myth.

voicesforvaccines.org

🆕🔥 State of the art review article @cmicomms.bsky.social Approach to Clostridioides difficile Diarrheal Infection ( CDI) Excellent discussions about the management of CDI #IDsky #mustread www.sciencedirect.com/science/arti...

🪪 𝐖𝐡𝐚𝐭 𝐢𝐬 teamcubancard.com? Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.

Also given our HHS Secretary's comments about fetal cells in vaccines... here's a post I made about that: open.substack.com/pub/deplatfo...

Cool table from @bradspellberg.bsky.social of RCTs of vaccines, in case anyone honestly believes there have been no RCTs of today's routine childhood vaccines: www.bradspellberg.com/vaccine-rcts

🆕🔥Case-control study @bradspellberg.bsky.social Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC jamanetwork.com/journals/jam...

Just found Dr. Hotez here on Bluesky. 20,000 of you already knew he was here. Great follow. bsky.app/profile/pete...

"most areas do not have experts in mycology" #IDSky @msgerc.bsky.social www.idse.net/Fungal-Infec...

Cosmetic Plastic Surgery Meningitis Mexico Mommy Makeover

Twenty-four patients who underwent cosmetic surgeries during 2023 in two clinics in Mexico developed <em>Fusarium solani </em>meningitis.

idse.net

This #FINEHEART pooled analysis, published in #JACC, demonstrated that finerenone significantly reduced the risk of new-onset atrial fibrillation/atrial flutter across the CKM spectrum. www.jacc.org/doi/10.1016/... #AFib

Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis

jacc.org

'Lipid-related atherosclerotic risk is most accurately reflected by the total count of apoB-P and is largely unaffected by the major particle type (VLDL, LDL) or size. Elevated count of Lp(a) adds additional risk' #apob #lpa apo(b) apolipoprotein b #ldl #cholesterol academic.oup.com/eurheartj/ad...

ApoB-containing lipoproteins: count, type, size, and risk of coronary artery disease

AbstractBackground and Aims. Apolipoprotein B concentration reflects the number of atherogenic lipoproteins and is recognized as a key lipid risk marker. W

academic.oup.com

'Defining and subphenotyping ARDS' www.sciencedirect.com/science/arti...

Defining and subphenotyping ARDS: insights from an international Delphi expert panel

Although the definition of acute respiratory distress syndrome (ARDS) has undergone numerous revisions aimed at enhancing its diagnostic accuracy and …

sciencedirect.com

procedural sedation protocol, versed and ketamine

josh farkas 💊@pulmcrit.bsky.social · last yr.

MidaKet for procedural sedation 😁 This is my go-to strategy for procedural sedation in sick, non-intubated patients. Start with a mildly obtunding dose of midazolam, then add a moderate dose of ketamine. Results in dissociative anesthesia & good resp/cardiovascular stability. 🧵 1/6 #EMIMCC

Updated vaccine RCT table looking amazing! Sorted for vaccine type, now more interactive in table, can click directly on the pubmed links in the table to go to the manuscripts. bradspellberg. www.bradspellberg.com/vaccine-rcts

Yes, actually in one of my responses on Twitter I wrote that I try to keep the tip of the CVC at least 5cm away from the tip of the dialysis catheter

'ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC'

Shai@shaiuk.bsky.social · last yr.

Similarly, am a proponent of CVC and Vascath placed in the same vein - pref RIJV. Another tip is to ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC - specifically vasoactives. Study below demonstrates this with an Abx model in piglets. #EMIMCC

🔴New publication in the CCI journal!🔴 Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support. Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai! 📖 Full Text: onlinelibrary.wiley.com/share/author...

'RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factor' #critcaresky #cccsky #ecmo #vv-ecmo #emimcc

Matt Siuba@zentensivist.bsky.social · last yr.

New 📝 We know RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factors (hypercapnia etc) We don’t understand RV function dynamically over time on ECMO…

I was interviewed for this excellent report in @Jamanews by Jennifer Abassi on the new discovery on apoB /LDL receptors interaction made by the @nih_nhlbi Lipoprotein lab led by Alan Remaley. [NB -it was not I who used the terms good and bad] jamanetwork.com/journals/jam...

New Insights On LDL Cholesterol

This Medical News article discusses recent landmark work to visualize the structure of the cholesterol-carrying low-density lipoprotein (LDL) particle bound to its cell surface receptor.

jamanetwork.com

Senator Chris Van Hollen met with Kilmar Armando Abrego Garcia in San Salvador. 💚

“We no longer have all the mechanisms in place to learn from those situations and prevent the next outbreak from happening,” www.yahoo.com/news/deadly-...

A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it

A foodborne illness linked to lettuce ripped across 15 states last November, sickening dozens of people and killing one. But the federal government chose not to publicize it.

yahoo.com

Soon after, DOGE installed a virtual system inside the agency’s servers that operated in secret. This system left no logs, no trace of its activity, and was removed without a record of what had been done.