The obesity epidemic split in two and we‘re only paying attention to one half. Childhood obesity stopped rising in the 1990s in many rich countries and may be declining in some. In most low- and middle-income countries it‘s still accelerating, often past wealthier nations. How can we bend the curve?

Obesity rise plateaus in developed nations and accelerates in developing nations - Nature

Global analysis of obesity trends from 1980 to 2024 in 200 countries and territories using data from 4,050 population-based studies reveals that framing obesity as a single global epidemic masks the h...

nature.com

🧠🍽️ Oral small-molecule GLP-1R agonists suppress hedonic feeding via a discrete CeA neuronal population that dampens dopamine release in the nucleus accumbens. Distinct from hypothalamic satiety circuits 👀 www.nature.com/articles/s41... #science #neuroskyence #ingestivebehavior

A brain reward circuit inhibited by next-generation weight-loss drugs in mice - Nature

Humanized glucagon-like peptide 1 receptor (GLP1R) mouse models are used to investigate the neural circuitry through which small-molecule GLP1R agonists modulate feeding, with implicati...

nature.com

NIH said: „study both sexes“ - but are researchers doing it? New study reviewed NIH funded papers: 61% include both sexes ✅, but only 44% analyzed data by sex ❌ with the biggest gap in animal studies. And: women-led author teams were 2.2x more likely to do sex based analysis. #sexdifferences 🧪

Incorporation of the National Institute of Health (NIH) sex as a biological variable policy by R01 grant awardees - Communications Medicine

Warden et al. analyze 574 NIH-funded publications (2017–2024) to assess implementation of the Sex as a Biological Variable policy. They find that most studies include both sexes, but fewer than half a...

nature.com

🔥PCOS has long been framed as a reproductive disorder. This review makes a compelling case that it’s fundamentally metabolic: androgen excess doesn’t just disrupt ovulation, it acts on the brain, liver, fat, pancreas, and muscles to drive obesity, insulin resistance, and metabolic disease. #science

Androgen actions in metabolic tissues in polycystic ovary syndrome

Abstract. Polycystic ovary syndrome (PCOS) is a common reproductive disorder characterized by irregular ovulation, cyst-like follicles on the ovaries, and

academic.oup.com

Fantastic work by my colleagues covering sex-specific responses to glucagon receptor agonism and modulation of fgf-21 axis in mice:

Christoffer Merrild@c-merrild.bsky.social · 5mo ago

I am proud to have done this work alongside @johansenvbi.bsky.social under the supervision of Pablo Ranea-Robles and @clemmensenc.bsky.social at @cbmr.science, University of Copenhagen. Curious to learn more? Read it here: doi.org/10.1113/JP28...

🍽️🧠 Can GLP-1 drugs protect against Alzheimer‘s? Preclinical data say yes, consistently reducing toxic plaques and tau. But clinical trials haven’t kept up yet. Exciting biology, but we still need better clinical evidence. New systematic review by Corcoran and colleagues. #neuroskyence #science

The effects of GLP-1 receptor agonists on Alzheimer's pathophysiology: A systematic review

The incidence of Alzheimer's disease (AD) is increasing globally but there are limited effective therapies available. Recently, evidence has demonstra…

sciencedirect.com

🗓️22-25 June 2026 Brussels: #ESMHSummerSchool for young journalists on #Science #Communication in the age of #AI 👉You can now apply: wp.me/panTdn-4vj #SciComm @linagalvez.eu @europeanjournalists.org @wfsj25.bsky.social @stinaborchers.bsky.social @pierregirard.bsky.social @josecepeda.bsky.social

ESMH Summer School 2026 - Call for young journalists and content creators - ESMH

Are you a young journalist writing about science and technology? Do you have questions about the impact of Artificial Intelligence (AI) on newsrooms,

wp.me

Despite the widespread use of GLP-1 analogs, a significant gap remains: most preclinical and clinical studies fail to consistently include or analyze sex-disaggregated data. This oversight is critical, as women now represent over 75% of young patients using these therapeutics. #Ozempic #Wegovy 🧪

GLP-1 and Its Analogs: Does Sex Matter?

Abstract. While obesity and diabetes are prevalent in both men and women, some aspects of these diseases differ by sex. A new blockbuster class of therapeu

academic.oup.com

I casually told a friend: "Wouldn’t it be cool to visit the European Parliament one day?" But when I said that I wasn't expecting I would actually visit as a speaker. 🇪🇺🤭🧵 #scicomm

Report: #ESMHSummerSchool 2025 on #scicomm in a nutshell 👉 wp.me/panTdn-4iu #journalism #digital #disinformation @linagalvez.eu @cameronbrick.bsky.social @eloisadelpino.bsky.social @stinaborchers.bsky.social @alokjha09.bsky.social @pavlahubalkova.bsky.social @efsj.bsky.social

ESMH Summer School 2025 in a nutshell - ESMH

From 24 -26 June 2025, young journalists from across Europe came together at the European Parliament in Brussels for the European Science-Media Hub (ESMH)

wp.me

Neue #Fortbildung! Am 20. & 21. November, jeweils 9.00-12.30 Uhr (inkl. Pausen), bieten wir den Online-Workshop “Grundlagen der Wissenschaftskommunikation” an. Bis zum 04. November können @hhu.de Wissenschaftler*innen ihre Interessenbekundung einreichen: www.buergeruni.hhu.de/stabsstelle-...

‼️🚨 postdoc position 🚨‼️ I am looking for a postdoc in psychoneuroimmunology - come join our group to work on sickness behavior in humans 🤒🦠 at Karolinska Institutet @ki.se !! ki.varbi.com/en/what:job/... deadline July 31st @pnirs.bsky.social #neuroskyence #PsychSciSky #interoception

Postdoctoral Researcher in Psychoneuroimmunology

Do you want to contribute to improving human health? Join a dynamic and inclusive research group at the forefront of psychoneuroimmunology, where we investigate the interplay between behavior, brain f

ki.varbi.com

Looking to start or move your lab? Come and join our wonderful department! This search is particularly targeted at molecular/cellular researchers with expertise in new therapeutic modalities - see thread below and add for more details, and feel free to reach out for more info! 🧠📈🧪

Andrew MacAskill@macaskillaf.bsky.social · last yr.

🚨🚨Job Alert🚨🚨!! Neuroscience, Physiology and Pharmacology are recruiting a new lecturer/associate professor! an amazing opportunity to join our fantastic dept! @ucl.ac.uk @ucllifesciences.bsky.social @uclnpp.bsky.social post here: www.nature.com/naturecareer...

🧠🍽️ A "hunger switch" in the nose? Smelling food activates a pathway from the olfactory bulb to medial septum glutamatergic neurons in mice, triggering anticipatory satiety: making them feel full before eating. This circuit works in lean mice but is disrupted in obesity. #neuroskyence 🧪

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism

The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

nature.com

🍽️ New study shows that “mini-ghrelins” (short peptides from ghrelin breakdown) can bind and block the ghrelin receptor without triggering its effects. Instead of being inactive leftovers, they may actively inhibit ghrelin’s hunger-inducing actions. #neuroskyence #science #ingestivebehavior

Mini-Ghrelins: Functional Characterization of N-terminal Peptides Derived from Ghrelin Proteolysis in Male Samples

Abstract. Some evidence suggests that ghrelin in plasma undergoes proteolytic processing, leading to the generation of shorter peptides containing the bioa

academic.oup.com

🍽️ New from our lab: Oxytocin isn’t just about love, it also helps us swallow. Knocking down oxytocin receptors in the vagus nerve reduced food intake and impaired esophageal function in rats, especially in males. 🔗 insight.jci.org/articles/vie... #neuroskyence #science #vagusnerve

That’s a wrap! Successfully defended my PhD yesterday! 🥳 #PhDone #Phinished #PhD #Neuroskyence

Hello Bluesky! Our students are running a short survey on interoception, ADHD, and autism. If you’ve got a few minutes, they’d be so grateful if you could take part — and help spread the word! 🔗 docs.google.com/forms/d/e/1F... #psychscisky

Aarhus University Student Survey

This questionnaire will take approximately 15- 25 minutes to complete. Please answer in a safe environment and as truthfully as possible. As a neurodiverse research team, we prioritize the comfort an...

docs.google.com

The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research | Nature Metabolism Great collaboration led by Satchin Panda and team! Happy to contribute. Time to take timing into consideration!! www.nature.com/articles/s42...

The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research - Nature Metabolism

This broad group of authors summarizes the impact of circadian factors on metabolic biology and offers recommendations on how to account for and report biological, environmental and experimental facto...

nature.com

High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration @jimmunol.bsky.social doi.org/10.1093/jimm...

A mechano-sensitive ion channel found in adipose tissue. Sensory innervation, but for what? Adipocyte hypertrophy? Fibrosis? Still a lot biology to be discovered I think. We also see some PIEZO2 and PIEZO1 expression in our data! www.cell.com/cell-me... 🧪

Everytime #brainawarenessweek comes up I can’t help but think it’s about raising awareness that we own a brain. But considering the recent political developments this reminder might be needed?

🧠🍽️ #Amylin acts in the central amygdala (CeA) to regulate feeding & motivated behavior We show that CeA amylin signaling is critical for appetite suppression, macronutrient selection & body weight control. Disrupting this pathway leads to hyperphagia & weight gain. #Neuroskyence 🧪 #ObesityResearch

From the pancreas to the amygdala: New brain area critical for ingestive and motivated behavior control exerted by amylin

Molecular biology; Neuroscience

cell.com

🧠🍽️ Satiety neurons that make you crave sugar? 🍬 New research shows that POMC neurons, typically linked to appetite suppression, release opioids in the thalamus, flipping the switch to increase sugar intake. #neuroskyence 🧪 #appetite

Thalamic opioids from POMC satiety neurons switch on sugar appetite

High sugar–containing foods are readily consumed, even after meals and beyond fullness sensation (e.g., as desserts). Although reward-driven processing of palatable foods can promote overeating, the n...

science.org

Behind the scenes 👀

Stina Börchers, PhD@stinaborchers.bsky.social · 2y ago

🚨New study alert! We used resting-state fMRI in rats to investigate the effects of GLP-1 and amylin on brain activity and functional connectivity. The results show sex-specific differences in neural responses ⬇️ #GLP1 #amylin #neuroskyence

Exciting to see part of the work from my visit at @pennstateuniv.bsky.social published!

Stina Börchers, PhD@stinaborchers.bsky.social · 2y ago

🚨New study alert! We used resting-state fMRI in rats to investigate the effects of GLP-1 and amylin on brain activity and functional connectivity. The results show sex-specific differences in neural responses ⬇️ #GLP1 #amylin #neuroskyence

🚨New study alert! We used resting-state fMRI in rats to investigate the effects of GLP-1 and amylin on brain activity and functional connectivity. The results show sex-specific differences in neural responses ⬇️ #GLP1 #amylin #neuroskyence

Sex-specific signatures of GLP-1 and amylin on resting state brain activity and functional connectivity in awake rats

Gut-produced glucagon-like peptide-1 (GLP-1) and pancreas-made amylin robustly reduce food intake by directly or indirectly affecting brain activity. …

sciencedirect.com

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social! academic.oup.com/endo/article... 🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

GLP-1 and the Neurobiology of Eating Control: Recent Advances

Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

academic.oup.com

Two years ago I went to the US as a visiting researcher during my PhD. Now our paper from one of the projects was accepted for publication 🎉 Hope to share it with you soon!! #GLP1 #amylin

Just submitted all papers that are going into my PhD thesis for evaluation. Hopefully the examination committee approves them so that I can defend in May 🤞🏻 #PhDthesis