A great new resource for future comparisons across model systems, species, and disease states, on @biorxivpreprint.bsky.social: a consensus atlas of human brain development, identifying cell type-specific maturation trajectories across the lifespan 🧪🧬🧠📈 www.biorxiv.org/content/10.6...

A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespan

Human neurodevelopment is a continuous process that begins prenatally and extends into postnatal life. Current transcriptomic datasets are limited, fragmented across analytical frameworks, precluding ...

biorxiv.org

Our new study, led by the amazing @alex john asks how thalamic nuclei mature differently across childhood and adolescence, and how structural and functional development are linked. doi.org/10.64898/202...

Nucleus-level thalamic organization anchors multimodal signatures of thalamocortical maturation

The human thalamus is composed of multiple nuclei that differ in structure and function. From early development onwards, these nuclei form reciprocal, nucleus-specific connections with the cerebral co...

doi.org

🧠 New work showing prominent and widespread 𝘪𝘯 𝘷𝘪𝘷𝘰 pre-synaptic terminal reductions in people with schizophrenia.🧠 nature.com/articles/s41... Strongest effects in left hemisphere, but synaptic loss didn't track with MRI grey matter alterations, but did align with..👇1/4

Widespread synaptic density loss in schizophrenia follows molecular and network architecture - Molecular Psychiatry

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

nature.com

Interested in the principles shaping connectome architecture? See our latest in @cp-cell.bsky.social led by F Normand @nsb-lab.bsky.social A simple model using geometric eigenmodes captures cortical connectomes of different species. Paper: tinyurl.com/3r43spf5 Thread: tinyurl.com/vx74hp6u

Now online! Geometric constraints on the architecture of mammalian cortical connectomes

Geometric constraints on the architecture of mammalian cortical connectomes

The origins of the cortical connectome’s complex topology and region-specific topography remain unclear, motivating a search for underlying physical principles. A neural-field-theory model that prioritizes connections between regions that facilitate the excitation of the resonant geometric eigenmodes of the cortex and reproduces topological and topographical features of diffusion-MRI and tract-tracing connectomes across five mammalian species and multiple spatial scales, indicating a universal geometric basis for connectome architecture.

dlvr.it

New paper in the Cortex Special Issue on Conceptual Knowledge! ✨ Erica Adezati, Daniel Mirman et al. show that different manipulations of evolving mental models of narratives recruit partly distinct neural systems that exhibit differential sensitivity to social vs non-social content 🧠 1/🧵

Benchmarking spatial interpolation methods for brain maps https://www.biorxiv.org/content/10.64898/2026.04.27.721143v1

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

Honoured to be speaking at today's Prize-winners' session of the @britishneuro.bsky.social Member's Meeting 🏆 Come hear about Credibility in Neuroscience, and our paper with @helenagellersen.bsky.social 🧠 We compared 768 fMRI brain network pipelines - so you won't have to! doi.org/10.1038/s414...

Systematic evaluation of fMRI data-processing pipelines for consistent functional connectomics - Nature Communications

The effects of different choices on preprocessing pipelines for functional connectomics remain unclear. Here, the authors systematically evaluate a multitude of pipelines on resting-state fMRI, reveal...

doi.org

British Neuroscience Association@britishneuro.bsky.social · 4mo ago

The BNA Members’ Meeting programme is now live! Join us online 22–23 April for Rapid-fire talks, research communications, posters and more. Free for BNA members - join instantly from £11/year. Explore the full programme and register via bna.org.uk

Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 www.biorxiv.org/content/10.6...

Comparative anatomy of brain metabolism in human and macaque (and other species). The dichotomy between glucose as fuel and glucose for tissue building is conserved across species. @moohebatpe.bsky.social and @misicbata.bsky.social www.biorxiv.org/content/10.6...

Bridging Histology and Tractography: First In Vivo Visualization of Short-Range Prefrontal Connections Informed by Primate Tract-Tracing onlinelibrary.wiley.com/doi/full/10....

Bridging Histology and Tractography: First In Vivo Visualization of Short‐Range Prefrontal Connections Informed by Primate Tract‐Tracing

We provide the first in vivo visualization of the prefrontal cortex's short-range connections by guiding diffusion tractography with past histological findings. This approach accurately reconstructs ...

onlinelibrary.wiley.com

Thalamocortical constraints on areal connectivity in the developing human brain https://www.biorxiv.org/content/10.64898/2026.03.24.714079v1

A retinotopic wiring principle of the human brain https://www.biorxiv.org/content/10.64898/2026.04.03.716412v1

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️

NIH is requesting comments on a new draft policy that may require human brain imaging data (and other data) from nih-funded research to only be shared via controlled access, & only with certain countries. I suggest neuroimagers read closely & submit comments by 3/18. osp.od.nih.gov/comment-form...

Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/jour... How do diverse synapses relate to the spatial patterning of whole-brain dynamics? Justine Hansen explores @plosbiology.org ⤵️

How may rare vs. common genetic variation separately influence how our brains – and their complex folding patterns – take shape? 🧬 🧠 Check out our new preprint (and final work from my PhD!) out now! ( + thread below) www.biorxiv.org/content/10.6...

We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, “Two Axes of White Matter Development”, is now out in @natcomms.nature.com! 🛣️🧠✨ 🔗 bit.ly/wm2axes

🚨 New Paper: Controlling the Human Connectome with Spatially Diffuse Input Signals Now in press at Communications Biology! www.nature.com/articles/s42...

The strongest version of this illusion I’ve seen! Absolute head-wrecker!

Longitudinal quantitative streamline tractography: robust estimation of white matter connectivity differences | bioRxiv www.biorxiv.org/content/10.6...

Interested in cortical wave dynamics? Check out our review on the physics, physiology, and psychology of cortical waves led by J Cruddas with @jchrispang.bsky.social, out now in @cp-neuron.bsky.social: www.sciencedirect.com/science/arti...

Traveling waves. Your brain has them. There must be a reason. Cortical traveling waves in time and space: Physics, physiology, and psychology www.cell.com/neuron/abstr... #neuroscience

Cortical traveling waves in time and space: Physics, physiology, and psychology

Cruddas et al. reviewed how core concepts from wave physics relate to cortical wave physiology and psychology. They examined how cortical waves emerge, how they facilitate coordinated, hierarchical, a...

cell.com

📢Maths in the Brain Workshop 2026 in Melbourne. We will bring together researchers across Australia with a shared interest in understanding the brain from a quantitative perspective. This year's keynote is delivered by Professor James Cole, University College London. 1/4🧵

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...

Our latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out: www.biorxiv.org/content/10.6... For a full thread, see: x.com/_victorbarne...

Paper alert: Our study led by @evapillai.bsky.social and @sudimukherjee.bsky.social showing that mechanical properties of the #brain actively shape the molecular landscape during development and #axonpathfinding is finally out! www.nature.com/articles/s41... @pdncambridge.bsky.social @fau.de @MPZPM

Long-range chemical signalling in vivo is regulated by mechanical signals - Nature Materials

Tissue stiffness mediated by Piezo1 is shown to regulate the expression of diffusive guidance cues in the developing Xenopus laevis brain, revealing a crosstalk between mechanical signals and long-ran...

nature.com