Tessera
Folgen

Weinan Sun

@sunw37.bsky.social

Neuroscience, Artificial Intelligence, and Beyond. Assistant professor at Cornell Dept. of Neurobiology & Behavior

25 Posts257 Follower64 Folgt
Virginie M. S. Ruetten@vmsruetten.bsky.social · 11mo ago

Thanks Misha for the shout-out! It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.

Misha Ahrens@mishaahrens.bsky.social · 11mo ago

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

LaurenGuillette.bsky.social@laurenguillette.bsky.social · last yr.

New #Outlook #PsynomLB 'Emergence of orthogonal hippocampal representations during spatial learning' https://bit.ly/4mlOXQa by Prof. Vern Bingman @BGSU_Biology about the recent paper https://bit.ly/4jZO0eT by @sunw37 @JohanWinn @CornellNBB et al. @nature @Psychonomic_Soc

Emergence of orthogonal hippocampal representations during spatial learning

Learning & Behavior - Sun et al. (2025) reveal the progressive, dynamic changes in the response properties of thousands of hippocampal neurons as mice learn a conditional discrimination while...

bit.ly

AntonioFR@antferrui.bsky.social · last yr.

Excited to share our latest story! We found disentangled memory representations in the hippocampus that generalized across time and environments, despite the seemingly random drift and remapping of single cells. This code enabled the transfer of prior knowledge to solve new tasks

Kristin Branson @kristinmbranson.bsky.social · last yr.

We read "Large Concept Models" in our reading group. It models language at the sentence resolution - "concepts". We had lots of thoughts about it! You can read them in our new Janelia CVML blog post: janelia-cvml.github.io/blog/posts/L... #ML #AI #Janelia @adjavon.bsky.social @bogovicj.bsky.social

Large Concept Models: Language Modeling in a Sentence Representation Space – Janelia CVML

Summary of and thoughts on Meta’s recent paper

janelia-cvml.github.io

Jason Keller@neurojak.bsky.social · last yr.

(1/11) Today I preprinted a lot of work from my postdoc with @dudman.bsky.social, which started with a question of how the nervous system balances flexibility with efficiency of learning. The thread below gives some background.... www.biorxiv.org/content/10.1...

Cortical control of innate behavior from subcortical demonstration

Motor control in mammals is traditionally viewed as a hierarchy of descending spinal-targeting pathways, with frontal cortex at the top. Many redundant muscle patterns can solve a given task, and this...

biorxiv.org

mark cembrowski@markcembrowski.bsky.social · last yr.

delighted to share our work revealing a new type of excitatory hippocampal neuron we call the "ovoid cell", which has really exquisite properties relative to adjacent pyramidal cells! superb work of first-author @adriennekinman.bsky.social and many others in the lab www.nature.com/articles/s41...

Atypical hippocampal excitatory neurons express and govern object memory - Nature Communications

Pyramidal cells are classically thought to comprise the excitatory output of the subiculum. Here, the authors show the existence of “ovoid cells”, excitatory subiculum neurons with specialized gene ex...

nature.com

Alex Kwan@alexkwan.bsky.social · last yr.

Can whole-brain imaging of cellular c-Fos signals be used to classify #psychedelics? 🧠🔬💊 Our study by @aboharbf.bsky.social and @pashadavoudian.bsky.social, developing an imaging and machine learning pipeline to test a panel of psychoactive drugs. Paper here 👇 www.nature.com/articles/s41...

Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression - Nature Communications

A challenge in psychiatric drug discovery is to predict the therapeutic potential of a novel compound. Here, the authors show that brain-wide imaging of immediate early gene expression can be used to ...

nature.com

@nspruston.bsky.social · last yr.

I’m excited about this collaborative project by @sunw37.bsky.social, @johanwinn.bsky.social, and many other talented contributors. Read about how our @hhmijanelia.bsky.social team imaged thousands of neurons in mouse hippocampus as mice learned cognitive tasks over several days: hhmi.news/4hXIp7r

Mapmaking in the mind: new research details how the brain builds mental maps of the world

To see how cognitive maps form in the brain, researchers used a Janelia-designed, high-resolution microscope with a large field of view to image neural activity in thousands of neurons in the

hhmi.news

Weinan Sun@sunw37.bsky.social · last yr.

1/12 How do animals build an internal map? In our new paper, we tracked thousands of mouse CA1 neurons over days/weeks as they learned a VR navigation task. @nspruston.bsky.social & co-1st author @johanwinn.bsky.social Video: www.youtube.com/watch?v=yw_4... Paper: www.nature.com/articles/s41...

Ezekiel Williams@ezekielwilliams.bsky.social · last yr.

Do I like this so much because it's a fantastic bit of science or because it's a fantastic job of doing science communication?!? Probably both. Regardless, awesome work that is worth checking out:)

Weinan Sun@sunw37.bsky.social · last yr.

1/12 How do animals build an internal map? In our new paper, we tracked thousands of mouse CA1 neurons over days/weeks as they learned a VR navigation task. @nspruston.bsky.social & co-1st author @johanwinn.bsky.social Video: www.youtube.com/watch?v=yw_4... Paper: www.nature.com/articles/s41...