New paper: Spinal circuitry modeled for locomotion using spatial transcriptomics and cell-type projections. Local excitation, long-range inhibition, and a longitudinal skew—an asymmetric "Mexican hat"—give rhythm, rotational dynamics, and gait, with no pacemakers. www.nature.com/articles/s41...

🚨 Want to start your lab in Marseille on a broad neuronal/brain development theme? There's an exciting tenure track opportunity at @inp-marseille.bsky.social and others Marseille institutes! Check more details here: neuro-marseille.org/en/blog/juni... or contact me if you have any question

Is This the End of the Endless Frontier? America’s prosperity, health, and technological leadership were built on an idea: sustained investment in fundamental research creates discoveries that transform society in ways no one can predict. time.com/article/202... 1/3

Is This the End of the Endless Frontier?

“Our country needs a new consensus on how to support science,” write Eric and Wendy Schmidt.

time.com

3 years ago I wrote this piece for @theatlantic.com about why we mustn’t take public health for granted. This is long before this admin’s deep cuts to public health. With the massive Cyclospora outbreak, I couldn’t help thinking about my own warning from the past.

We have a new preprint! By studying neuronal heterogeneity in CA3, we found a weird but powerful new feature in the hippocampal circuitry! 🧠 #neuroskyence 🧵.. Morse-Mora et al. | Hippocampal CA3 forms a two-layer network of molecularly distinct cell types in mice and humans doi.org/10.64898/202...

“There's a piece of NIH's mission Atlas never mentions, because it doesn't fit his story: NIH doesn't just fund experiments, it funds people. Training grants, fellowships, career development programs, and research project grants that carry graduate students and postdocs through their formative yrs”

@hellabores92.bsky.social · 4w ago

Excellent response from Dr. Bertagnolli to the article from Scott Atlas www.linkedin.com/pulse/dont-a...

This paper is an absolutely beautiful combination of a deep set of cognitive ideas, a super creative task, a surprisingly impressive behaviour, and an elegant modelling framework. One of my favourite things in the last year.

Neuron@cp-neuron.bsky.social · last mo.

Musk says not a single person has died due to him axing USAID. Sadly, part of my job involves tracking aid spending. So here’s a thread with just some of the people who lost their lives because of USAID cuts

This shift comes at a large cost to be borne primarily by young investigators at Janelia, at a time when scientific environment is exceptionally uncertain. How innovative it is to repeat, in fish, what was done in flies remains an open question tbd. Not an open question: immediate cost and who pays

The Transmitter @thetransmitter.bsky.social · last mo.

HHMI’s Janelia Research Campus will close two of its programs dedicated to rodent work, @thetransmitter.bsky.social has learned. #neuroskyence By @callimcflurry.bsky.social www.thetransmitter.org/community/ex...

Excited to move to the Department of Neuroscience at the University of Minnesota in the fall. We will continue our work on neuromodulators and behavior. Positions available in the lab. Please get in touch if interested, and share broadly! hr.myu.umn.edu/jobs/ext/374... hr.myu.umn.edu/jobs/ext/374...

Excellent and thought-provoking essay by Ted Chiang. [gift link] www.theatlantic.com/philosophy/2...

No, Artificial Intelligence Is Not Conscious

Taken to its logical conclusion, this line of thinking is absurd—and damning.

theatlantic.com

Incredible! Scientists receive a rare standing ovation after announcing that a new treatment can double the survival time for pancreatic cancer, the deadliest cancer which was once considered “undruggable.” When we fund and support science, we can achieve anything! (Video: Dr. Wish Dhillon)

Neuropixels + Optogenetics = Neuropixels Opto Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors. Today in @natmethods.nature.com doi.org/10.1038/s415... Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.

OMB just published 412 pages in the Federal Register (Docket OMB-2026-0034) giving political appointees authority to terminate any NIH grant, override peer review scores, and block you from publishing with federal funds. Comment period closes ~July 13. Thread 🧵

@fluketc.bsky.social and @dudman.bsky.social have hit it out the park again. In my (perhaps biased) opinion this - along with their previous papers - is field-defining work. www.science.org/doi/10.1126/...

Reward magnitude determines reinforcement learning efficiency

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

science.org

Cool new work from @dudman.bsky.social and @fluketc.bsky.social Reward magnitude determines reinforcement learning efficiency: www.science.org/doi/10.1126/...

Reward magnitude determines reinforcement learning efficiency

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

science.org

Great new paper from @dudman.bsky.social and @fluketc.bsky.social. It’s going to immediately change how we train our animals and make us think hard 🤔https://www.science.org/doi/10.1126/science.aeb0813

Reward magnitude determines reinforcement learning efficiency

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

science.org

Awesome results from @fluketc.bsky.social @dudman.bsky.social and team, both for dopamine field and for all that train animals in tasks www.science.org/doi/10.1126/...

Reward magnitude determines reinforcement learning efficiency

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

science.org

🚨 Ever wanted a simple way to control the activity of thousands of neurons? We introduce an all-optical raster photostimulation method to do just that! w/ @computingnature.bsky.social @marius10p.bsky.social #FluorescenceFriday #neuroskyence www.biorxiv.org/content/10.6... 1/n

Really pleased that this work with @dudman.bsky.social is now out in Neuron: A global dopaminergic learning rate enables adaptive foraging across many options

Neuron@cp-neuron.bsky.social · 3mo ago

Reminder that it's possible to set up a free personal website using GitHub pages: docs.github.com/en/pages Really straightforward to then use Jekyll to make something relatively nice (with the aid of your chosen LLM, of course...) Just updated my own using this approach: lauralgrima.github.io

GitHub Pages documentation - GitHub Docs

GitHub Pages turns any GitHub repository into a live website—no separate hosting required.

docs.github.com

Posting for Vibhu Sahni: Due to unforeseen circumstances the Burke Neurological Institute will have to terminate its research operations 5/22. There are international postdocs on visas who are looking for new homes. Please reach out to Vibhu if you can help

New preprint: Whole-body 3D kinematics of freely behaving 𝐷𝑟𝑜𝑠𝑜𝑝ℎ𝑖𝑙𝑎 New tech from @blobology.bsky.social & others at @hhmijanelia.bsky.social, which @ispizua.bsky.social and @elliottabe.bsky.social used to gain insight into 3D structure of locomotion & courtship www.biorxiv.org/content/10.6...

Spending on new medical research by the National Institutes of Health has fallen roughly $1 billion behind the pace of years past, delaying thousands of scientific projects. Story by Ben Mueller & @irenatfh.bsky.social Gift link: nyti.ms/4ctOSqM

Fascinating and really well explained in thread

Evan Gordon@gordonneuro.bsky.social · 3mo ago

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

Scientists just discovered new "controllers" of the brain's most elite security checkpoint. Jiefu Li & team at our Janelia Research Campus have ID'd proteins that help open & close the blood-brain barrier — a step toward treating Alzheimer's, Parkinson's, & more: hhmi.news/4mkrDT2.

"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."

Pancreatic cancer mRNA vaccine shows lasting results in an early trial

Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

nbcnews.com

No-cost workshop opportunities for grad students, postdocs, & trainees! Our Janelia Research Campus is accepting applications for 3 specialized, intensive workshops with presentation & networking opportunities. Accommodations, meals, & travel expenses covered: bit.ly/4roghP6. 🧪

New paper hot off the (pre-)press! We dig into the evolutionary origins of neural computations for behavioral control across mice, monkeys, and humans: www.biorxiv.org/content/10.6.... As our lab's first foray into comparative analysis of neural dynamics, I’m super excited about this work! 1/18

Excited to be co-organising a #cosyne2026 workshop with Alison Comrie on 'algorithms for learning from scratch'! With a great line-up of speakers, we'll be tackling the question of what processes enable naive biological & artificial agents to adapt to new situations. Info here: tinyurl.com/4u8enf7k

learningfromscratch

march 16th, workshop day 1 @ cosyne 2026

sites.google.com