Xtremo-Devo Lab @ WMU
@xtremo-devo-lab.bsky.social
Eco-Evo-Devo of killifish & kin. 🐟 Uncovering the 🧬 blueprints for life in extreme environments. Ex luto surgimus. #EcoEvoDevo #Killifish #WMU https://andrewwt.github.io/xtremodevo-lab/
My favorite conference! Hope to see you in Woods Hole!
Just a friendly reminder! We look forward to your abstracts!
Excited to see what’s next!
I am excited to open my lab at @ibioillinois.bsky.social in Spring 2027! We will use zebrafish & other fishy friends to reveal the genetic basis of large scale changes in the vertebrate body plan, and how this impacts both human health and evolution. Join me at UIUC! 🧬🧫🔬 www.hawkinslaboratory.com
📣 Abstract submission is OPEN for #AQMHD2026! 🐟🦑🪸 Join us Oct 17–21, 2026 at MBL in Woods Hole, MA for the 12th Aquatic Models of Human Disease Conference. Submit by Aug 10, 2026: docs.google.com/forms/d/e/1F...
AQMHD 2026 Abstract Submission
12th Aquatic Models of Human Disease Conference October 17–21, 2026 | Marine Biological Laboratory, Woods Hole, Massachusetts Submit one form per abstract. Complete all required fields and paste the ...
docs.google.com
Hello AQMHD community! The “final” #AQMHD2026 program is live—final, that is, until we add talks selected from submitted abstracts! 🐟🧬 Join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole, MA. Abstract submission opens soon—watch for details next week! aqmhd.org/program.html
Final Program | AQMHD 2026
Final program for the 12th Aquatic Models of Human Disease Conference
aqmhd.org
First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...
Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
biorxiv.org
#OTD 10 years ago we published the spotted #gar genome. 600+ citations later, we are proud of its impact on vertebrate genomics. @jpostlethwait.bsky.social Check out the new assemblies generated with @vertebrategenomes.bsky.social www.ncbi.nlm.nih.gov/datasets/gen... #EndlessFishMostBeautiful
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📢 Save the Date! The 12th Aquatic Models for Human Disease Conference (AQMHD) 🗓 October 17–21, 2026 📍 Marine Biological Laboratory, Woods Hole, MA Theme- Diving Deeper into Disease Biology: Emerging Models in Human Health #AQMHD #ModelOrganism #MBL #DiseaseBiology
"Medaka: A novel model for analyzing genome-environment interactions" by Kiyoshi Naruse & colleagues "Endemic to habitats spanning from 4 to 40°C and varying salinities, [medaka] combines broad ecological adaptability with experimental tractability." Read more: authors.elsevier.com/sd/article/S...
Super cool work on medaka by @ewanbirney.bsky.social and colleagues www.cell.com/cell-genomic... Includes an excellent summary from Ewan via linkedin... and I maintain that 'humans aren't special' 😊 www.linkedin.com/pulse/little...
The little fish that could.
Today sees the publication of a long awaited paper from my group. This has been.
linkedin.com
And it's out indeed! Huge congrats to @josanesousa.bsky.social, @gabrielalima19.bsky.social, @perezlouise.bsky.social & Hannah Schof! A true tour-de-force that highlights how emerging model systems can shed new light on long-standing macro-evolutionary questions. Go #axolotl, #polypterus #zebrafish!
It’s out! 🐟 We compared three regeneration superstars—axolotl, zebrafish, and Polypterus—to ask how animals regrow limbs and fins. We find shared core processes, and other programs fine-tuned by evolution in surprising, lineage-specific ways. tinyurl.com/mpftkn7y
Our Perspective article on Computational Strategies for Cross-Species Knowledge Transfer is now published in @natmethods.nature.com! This was a collab b/w @krishnanlab.bsky.social & @fishevodevogeno.bsky.social, led by the amazing Hao Yuan @yhbioinfo.bsky.social. 🧵 www.nature.com/articles/s41...
How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team! 🔗 tinyurl.com/3a8r9xy5
@snbogan.bsky.social @notothentoma.bsky.social @scotthotaling.bsky.social @paulbfrandsen.bsky.social et al. explore the evolution of type III antifreeze proteins in deep sea zoarcoid fishes. 🔗 doi.org/10.1093/molbev/msaf219 #evobio #molbio
Why are some species smaller than a paperclip while others grow longer than a school bus? How is body size evolution governed in animals? Out now in @pnas.org we tackle these longstanding questions through a genetic lens using my favorite group of fishes as our model!! www.pnas.org/doi/10.1073/...
Parallel shifts in differential gene expression reveal convergent miniaturization in fishes | PNAS
Body size variation in vertebrates is a complex polygenic trait, tightly correlated with numerous aspects of a species’ biology, ecology, and physi...
pnas.org
New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...
Zebrafish embryo undergoing gastrulation. Credit to Dr. Gopi Shah at EMBL. #ZebrafishZunday 🧪
👻 G-g-ghost? Nope, s-s-snailfish! 🤍 Meet the mesmerizing new addition to our Into the Deep/En lo Profundo exhibit, rough snailfish! These ethereal charmers live in the benthic zone, a scientific term for the seafloor.
Congrats @liujuan.bsky.social, our very own @zzhou32.bsky.social and all co-authors! Fintastic work!
New in @science.org, meet Acronichthys maccagnoi, a new species from Late Creatacous Canada that changes what we know about the origins and evolution of one of the most successful fish groups on Earth.
Update of our preprint on Inter-individual gene expression variability in fishes! We improved statistical analyses of continuous variables, and especially added machine learning on promoters which confirms cis-regulation of organ-specific expression variability. www.biorxiv.org/content/10.1...
Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs
Phenotypic variation among individuals plays a key role in evolution, since variation provides the material on which natural selection can act. One important link between genetic and phenotypic variat...
biorxiv.org
You're fin-tastic! 🐟🐠🌟🤩 Our fish community present #PASEDB2025! @nakamuralab.bsky.social @phernandez.bsky.social @patyschneider22.bsky.social @ischneider.bsky.social @xtremo-devo-lab.bsky.social @fishevodevogeno.bsky.social @homeobox.bsky.social and more! Help us to tag them
Our dear friend @ischneider.bsky.social receiving the Young Investigator Award from @evodevopanam.bsky.social! So incredibly deserved! #PASEDB2025 To infishity and beyond! Great work, Igor!
EvoDevotees, if you are at #PASEDB2025 and interested in either of these job opportunities for Fish Facility Manager or Presidential Postdoc at Michigan State U, let’s grab a coffee and chat #EndlessFishMostBeautiful @evodevopanam.bsky.social
#PanAmEvodevo2025 is about to start! Starting countdown, engines on! @fishevodevogeno.bsky.social @xtremo-devo-lab.bsky.social @patyschneider22.bsky.social
Our latest issue is now live! On the cover is a species of Asian noodlefish characterized by their transparency due to the absence of red blood cells, slender bodies and scaleless skins, and a poorly ossified skeleton. www.cell.com/current-biol...
We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something “like the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out 👇🧪🧬🐟 doi.org/10.1101/2025...
The Braasch Lab @fishevodevogeno.bsky.social will soon post a position to replace manager of our *Ancient Fish Facility* at Michigan State. Looking for aquaculturist excited for unusual 🐟 species (gar, bowfin, paddlefish, polypterus) + zebrafish. Pls send candidates our way (DM or braasch@msu.edu)!