Excited to see James' Genome-wide Absolute Quantification of Looping paper out in @natsmb.nature.com : www.nature.com/articles/s41... This has been in collaboration with @lucagiorgetti.bsky.social @leonidmirny.bsky.social @zechnerlab.bsky.social labs. Brief thread below on some key updates

Anders Sejr Hansen@andersshansen.bsky.social · 2y ago

Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...

(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack: Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)? A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): www.biorxiv.org/content/10.6...

(1/n) Super excited to share that our preprint is out today in @natsmb.nature.com with a new name "Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types" and more than 2x more data: www.nature.com/articles/s41... See also MIT News news.mit.edu/2026/how-chr...

Anders Sejr Hansen@andersshansen.bsky.social · last yr.

(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...

www.nature.com/articles/s41... An insighful study, leveraging MINFLUX to study chromatin dynamics by the @andersshansen.bsky.social lab @natsmb.nature.com . I am left wondering what if how we model chromatin with polymer simualtions needs rethinking, but surely many interesting findings here.

Join us at the LS2 #Theory #across #Biology chalk talk symposium! 12 June 2026 in Bern, CH. @lifesciswitzerland.bsky.social No movies that fail, no Mac to PC issues. Only the best ideas and exchange across biology from evolution and ecology to physics of life. meetings.ls2.ch/theory-acros...

Kinetic proofreading as a mechanism for transcriptional specificity: www.biorxiv.org/content/10.6... Very nice follow up to their review from last year genesdev.cshlp.org/content/39/1... Non-equilibrium models may be key to understanding specificity in transcriptional regulation!

Postdoc opening with us at EPFL! Experimental project on how ATP driven chaperone cycles keep proteins out of equilibrium. We will quantify energy use, kinetics, and functional outcomes, including clients whose native-like functional state is stable only by sustained chaperone action.

Our work on the interplay between loop extrusion and chromatin mechanics is finally out in @physrevresearch.bsky.social . Congrats @hosseinsalari.bsky.social for the hard work ! 👏 journals.aps.org/prresearch/a...

Daniel Jost - Physical Biology of Chromatin group@djost-physbiol.bsky.social · 10mo ago

New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social www.biorxiv.org/content/10.1...

Come on join us! We are searching for the next technical associate to join our lab ~Summer 2026. This could be a great position for someone who is graduating this spring and is looking for 2 more years of research experience before starting their PhD: careers.peopleclick.com/careerscp/cl...

The EMBO Young Investigator Network consists of young investigators, installation grantees and global investigators. 🧪 Find more information on the individual programmes here: https://www.embo.org/the-embo-communities/embo-young-investigator-network/ #LifeSciences #research #funding

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

See this recent paper by @andersshansen.bsky.social that discovers similar microcompartmentalization during mitotic exit: www.nature.com/articles/s41...

Dynamics of microcompartment formation at the mitosis-to-G1 transition - Nature Structural & Molecular Biology

Goel et al. produce high-resolution three-dimensional genome structure mapping from mitosis to G1 phase to show unseen interactions between enhancers and promoters in prometaphase. Polymer modeling in...

nature.com

An incredible ICTP initiative is our Postgraduate Diploma Programme. Rigorous one-year pre-PhD training for students from the Global South. I have personally seen this program transform the lives of those in the quant life sciences. Due Feb. 28 2026. Please share widely. www.ictp.it/news/2025/11...

Since more than a decade, our group has been exploring chemically active droplets, which are exciting since their size can be controlled. Yet, we still do not fully understand this control even in the simplest models. Until a new preprint (arxiv.org/abs/2512.02542) spearheaded by postdoc Guido...

Size control guidelines for chemically active droplets

Biological cells and synthetic analogues use liquid-liquid phase separation to dynamically compartmentalize their environment for various applications. In many cases, multiple droplets need to coexist...

arxiv.org

We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28! www.cam.ac.uk/jobs/univers...

I am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social 🥰 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🤩

Max Planck Institute of Molecular Cell Biology and Genetics@mpi-cbg.de · 8mo ago

Watch this video about the work of the research group of @agnestoth.bsky.social @mpi-cbg.de & @csbdresden.bsky.social. Agnes and her group work on protein plasticity and evolution. For her work, Agnes recently received the Schering Young Investigator Award 2025! youtu.be/lEpvGu3J63M?...

The most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.

I’m very excited to start this project — it brings together ideas that matured over many years and opens a long-term path for innovation in RNA modelling. 🍾 🧬

Bussi Lab@bussilab.org · 8mo ago

🎉Our group has been awarded a prestigious #FIS grant! #RNAScale - Exploring RNA Dynamics across Scales: From Base Pairs to Viral Genomes 👉 www.bussilab.org/fis3 We will soon open postdoctoral positions across several components of the project! An expression-of-interest form is already online.

One of our founding directors Anthony Hyman @hymanlab.bsky.social will become @embl.org Director General: www.mpi-cbg.de/news-outreac...

Anthony Hyman to become next EMBL Director General

Founding Director of MPI-CBG will lead Europe's life sciences laboratory

mpi-cbg.de

EMBL@embl.org · 8mo ago

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

Wonderful to see the beautiful preprint from Sabate et al now published - TADs are also dynamic structures in human cells, with remarkably similar parameters between mESCs and HCT116 cells www.nature.com/articles/s41...

Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176 #biophysics

Postdoc in Theoretical Biophysics

Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).

euraxess.ec.europa.eu

Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication. www.biorxiv.org/content/10.1... A🧵👇

Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.

Elise Cutts@elisecutts.bsky.social · 11mo ago

Hydra are ~basically~ immortal. Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads! This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️

Great work! Congratulations you all & especially to @carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...

NordenLab@nordenlab.bsky.social · 12mo ago

The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...

Our beautiful Hydra made the cover!!! 😍😍😍 An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de Actin fibers in blue, nuclei in orange.

Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.

Anaïs Bailles@anaisbailles.bsky.social · 12mo ago

Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...

Stretching the immortal Hydra

Dresden researchers show how cells can create a new organism from scratch by coordinating their mechanical properties.

mpi-cbg.de

Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...

Novel Research in Biological Artificial Intelligence

Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.

mpi-cbg.de

We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!

Max Planck Institute of Molecular Cell Biology and Genetics@mpi-cbg.de · last yr.

Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...