There are lots of exciting opportunities to join the in situ structural biology community at Leeds this Autumn - 2 studentships in the Cheney PhD program (astbury.leeds.ac.uk/cheney-phd/) and I am recruiting a PhD student and research assistant. Please share and send any future tomographers our way!

Cheney Scholarship PhD Programme : The Astbury Centre for Structural Molecular Biology - "Understanding Life in Molecular Detail"

Applications are open for 2 PhD student places.  Closing date for applications is Thursday 26 June, 5pm. Interviews will be held on 9th July 2026. The Cheney Scholarship is a prestigious 4-year PhD pr...

astbury.leeds.ac.uk

Great to see this out in its final form - congrats all on such a brilliant collaboration! 🎉

Simon Bullock@simonbullock11.bsky.social · 3mo ago

Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4). www.nature.com/articles/s41...

Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

Happy to share our latest work spearheaded by super talented PhD student Muyang Ren now out as a bioRxiv preprint. 'Motile ciliophagy promotes ciliary recycling under stress' www.biorxiv.org/content/10.6...

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

New preprint from the lab, looking at how multiple different adaptors interact with dynein! Work led by @amicoennio.bsky.social. Available now on BioRxiv: doi.org/10.64898/202...

Ennio@amicoennio.bsky.social · 3mo ago

New preprint! We asked a simple question: How do very different activating adaptors all activate dynein? Turns out: same architecture, wildly different implementations 🧵👇 doi.org/10.64898/202...

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

Add our first pre-print to your reading list? Using AF2 and MD, we've characterised structures and conformational ensembles of human rhomboid proteases - and revealed some surprises along the way. Feel v.lucky to work alongside Bryony & @robincorey.bsky.social! Please share: tinyurl.com/3h8r7f5y

The annual Dunn School DPhil studentship competition for 2026 is open for applications. We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested. www.path.ox.ac.uk/project/mech...

Mechanistic studies on axonemal dynein transport to motile cilia - Dunn School

Over 30 groups work at the Dunn School to uncover the molecular and cellular mechanisms underlying disease. Discover which research groups are accepting students for our next round of applications.

path.ox.ac.uk

Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. www.biorxiv.org/content/10.1...

Excited to share our latest work! We found transcription factor SPT6 and phosphorylated Pol II CTD help recruit U1 snRNP to elongating Pol II, allowing efficient co-transcriptional splicing. Glad to be featured in the Editors’ Highlights! www.nature.com/articles/s41... #splicing #cryoEM

Postdoc position in my lab: investigating how the microtubule motor protein dynein-2 works in cilia. Here's dynein-2 at work translocating microtubules - how is this activity regulated? How does dynein-2 malfunction in disease? Find out more and apply: my.corehr.com/pls/uoxrecru...

Great to see our story on dynein & kinesin co-dependence published www.nature.com/articles/s41..., and absolutely chuffed that it's made the front cover (thanks NSMB!). A brilliant News & Views too by Steven Markus www.nature.com/articles/s41.... Collab between @carter-lab.bsky.social & Straube lab🔬

Huge congrats both - so good to see this out in final form @chrisvanhoorn after all the meticulous and clever ways you approached this beast of an organelle. Stunning 🤩

@chrisvanhoorn.bsky.social · 2y ago

Our #CryoET paper on ciliary rootlet ultrastructure from mouse retina is now out in @elife.bsky.social! Have a peek with this video or dive deeper at bit.ly/3ZJzhgc. Big thanks to @carter-lab.bsky.social and #teamtomo. #CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science

Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.

Closing the scissor-shaped curve: Strategies to promote gender equality in academia

Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reac...

cell.com

Please share this PhD opportunity in my new lab in Bristol, using protein design/ engineering to understand and build molecular motors to control intracellular transport. Working with @markdodding.bsky.social and Prof Dek Woolfson. www.findaphd.com/phds/project... www.swbio.ac.uk/biomolecular...

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

A huge achievement - congrats to all! 🥳

Alessandro Costa@costalaboratory.bsky.social · 2y ago

Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps. www.nature.com/articles/s41...

The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology

Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...

nature.com

International Day of LGBQTIA+ People in STEM is TODAY! 🏳️‍🌈 And for those in Bristol (@bristoluni.bsky.social), check out the LGBTQ+ STEM mini-conference on Wednesday in C42 (BMS building), 1-5pm. Register via: forms.office.com/e/LxuMpa6nQF

Pride in STEM@prideinstem.bsky.social · 2y ago

November 18 is the International Day of LGBQTIA+ People in STEM! Today more than ever we want to stress the importance of communities, building connections, and raising each other up. Let's keep leaving our mark for the betterment of us all! 🏳️‍⚧️🏳️‍🌈 #QueerinSTEM prideinstem.org/lgbtstemday/

BSCB Women in #CellBiology prize 🧪 Deadline extended (15th Nov) The deal: UK-based scientist, running lab for < 7 years with 1+ senior author publication. Do you know someone who should be nominated? Maybe it's you? Details (a bit out of date): bscb.org/competitions...

❗️Exciting science alert!! Come join us at the BCA Winter Meeting at the MRC Laboratory of Molecular Biology, Cambridge, 6th December. Short talks available - a great opportunity for early career researchers to present.. bit.ly/4fDEqfZ

This year’s UK Membrane Trafficking Meeting is on Dec 16th at King’s College London (Guy’s Campus, London Bridge). Registration closes 9th December. Sign up is here. estore.kcl.ac.uk/conferences-... Thanks go to @J_Cell_Sci for sponsoring student/postdoc prizes!