Tessera
Folgen

adam grieve

@adamgrieve.bsky.social

Membrane protein signalling and turnover in neurons Sir Henry Dale Fellow at School of Biochemistry, University of Bristol grieve-lab.com

10 Posts1074 Follower567 Folgt
Ian Collinson@ianofbristol.bsky.social · 2mo ago

Apply here! meetings.embo.org/event/26-pro...

Advances and new frontiers in protein translocation across membranes

The organization of cells into membrane-bound compartments is fundamental to life, requiring proteins to cross these barriers through highly specialized translocation systems. Understanding these pro…

meetings.embo.org

Ian Collinson@ianofbristol.bsky.social · 2mo ago

Protein Traffickers Deadline for @embo.org workshop abstract submission now extended-19th June. Spaces for short talks available Grants available for childcare and accessibility needs @biologists.bsky.social travel bursaries for students and early career scientists. Apply now and repost

Ben Langmead@benlangmead.bsky.social · last yr.

Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.

HMMER - Wikipedia

en.wikipedia.org

Sean Eddy@cryptogenomicon.bsky.social · last yr.

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

Verena Kohler@verenakohler.bsky.social · last yr.

🔬 Hiring: Postdoctoral Fellow Seeking a bioinformatician/screening expert to be part of our team running genome‑wide screens, building data‑integration pipelines & validating hits in higher organisms. 🌱 2‑yr fellowship with tailored mentorship, leadership & science‑communication training

Bild
Aakriti Jain@aakritijain.bsky.social · last yr.

SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...

science.org

Andrew Porter@retropz.bsky.social · last yr.

Applications close today for this @uniofmanchester.bsky.social #DigitalNotebook #Metascience project, seasoned with #OpenResearch & served with helpings of #ResearchIntegrity and a side of #ResearchCulture Full details of everything on the menu below 👇 www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate_Metascience Project:Oxford Road

jobs.manchester.ac.uk

Andrew Porter@retropz.bsky.social · last yr.

Last few days to apply #Metascience post @uniofmanchester.bsky.social working with James Bird, @naubertbonn.bsky.social, Prof Andrew Stewart & me to investigate opportunities and barriers in deploying Electronic Research Notebooks (ERNs) www.jobs.manchester.ac.uk/Job/JobDetai... #ELN #OpenResearch

Text reads: We are recruiting a Research Associate for an exciting UKRI Metascience project Support researchers in moving from traditional methods of recording research......to digital-first Electronic Research Notebooks......enhancing data sharing, FAIR principles, re-use and collaboration Images show a person writing in physical notebook, holding a tablet computer while wearing lab gloves, and a big image of a blue 'share' button on a computer keyboard Apply by 24th March, Job reference: SAE-028173
adam grieve@adamgrieve.bsky.social · last yr.

Thank you Ines! I had such a lovely time visiting sunny York this week, sharing our science and chatting cell bio, neuroscience and proteases. Thanks for the invite, special thanks to the one and only @yorkyeast.bsky.social for top-notch hosting!

Bild
Ines Hahn@exdrososcientia.bsky.social · last yr.

We felt very honoured this week that @adamgrieve.bsky.social shared his exciting and brand new (!) results on the role of rhomboid proteases at synapses for the very first time in our #celldynamics series! Such a cool talk :) Watch out for some really exciting science!

Joan Chang@tranejoan.bsky.social · last yr.

Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out 👇🏻 #macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social www.biorxiv.org/content/10.1...

Macrophages promote collagen deposition through circadian regulation of fibroblasts

Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...

biorxiv.org

adam grieve@adamgrieve.bsky.social · 2y ago

Exciting opportunity in the newly minted McMillan lab in Liverpool. Kirsty is a great scientist and a top mentor for students - if you’re looking for a PhD and are interested in trafficking and neurodegeneration, do contact her!

Kirsty McMillan@mcmillanlab.bsky.social · 2y ago

I have a funded PhD studentship available to start in my new lab in 2025! If you are interested in Endosomal Biology, Astrocytes and Alzheimer’s Disease have a look: www.findaphd.com/phds/project... Please feel free to share.

Jez Carlton@jezcarlton.bsky.social · 2y ago

UK Membrane Trafficking 2024 Who doesn’t like a deadline that gets brought forward? Please register by 3rd December - King’s need longer to make the sandwiches than I previously thought! estore.kcl.ac.uk/conferences-... Programme coming soon!

UK Membrane Trafficking Meeting 2024 | King's College London eStore

Registration for the 2024 UK Membrane Trafficking Meeting, held at KCL.  Registration per person, to include sandwich lunch and coffee breaks and even

estore.kcl.ac.uk

adam grieve@adamgrieve.bsky.social · 2y ago

Amazing PhD opportunity to join an exciting new lab at Bristol Biochemistry - send your best students in Ferdos’ direction!

Ferdos Abid Ali@abidalilab.bsky.social · 2y ago

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

This scheme shows the cargo adaptor FHF in the middle with arrows pointing to distinct microtubule and actin-based motors (dynein-dynactin, KIFC1, KIF1C and myosins V, IX and X as well as Tropomyosin 1). It also shows a link to Rab5 marked early endosomes. The hypothesis is that FHF coordinates multi motor binding at the early stages of endocytosis. The PhD project would address the hierarchy of motor binding and how these motors coordinate to allow the newly formed vesicle to transition from the actin to MT cytoskeletal network.
Ferdos Abid Ali@abidalilab.bsky.social · 2y ago

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

This scheme shows the cargo adaptor FHF in the middle with arrows pointing to distinct microtubule and actin-based motors (dynein-dynactin, KIFC1, KIF1C and myosins V, IX and X as well as Tropomyosin 1). It also shows a link to Rab5 marked early endosomes. The hypothesis is that FHF coordinates multi motor binding at the early stages of endocytosis. The PhD project would address the hierarchy of motor binding and how these motors coordinate to allow the newly formed vesicle to transition from the actin to MT cytoskeletal network.
adam grieve@adamgrieve.bsky.social · 2y ago

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

Bild
Matthew Freeman@mjafreeman.bsky.social · 2y ago

Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...