Happy to see that my work from my (short but intense!) postdoc in London has finally seen the light of day as a preprint! 🎉 🎉 If you’re interested in how the human macula is prepatterned by Müller glia from the earliest stages of development, don’t miss the chance to check it out! 👁️

An early CYP26A1/CRYAA progenitor-glial domain marks the presumptive macular region during human retinal development

The human macula, a high-acuity retinal region essential for central vision, emerges early in development, but the cellular basis of its regional specialisation remains incompletely resolved. Building...

biorxiv.org

🚨 New pre-print alert! 🚨 Adult neural stem cell state and fate decisions are hidden within transcriptional heterogeneity. To find out how we decoded these heterogeneities to identify a molecularly encoded quiescence cycle, check out the pre-print on bioRxiv! doi: doi.org/10.64898/202...

We're very excited to announce the official launch of the Journal of Regeneration. Together with the amazing team from @pensoft.net and my two co-EICs Loriano Ballarin and Buki Rinkevich, it is such a pleasure to share this new platform for bringing together the regeneration biology community.

Journal of Regeneration

 Journal of Regeneration is an international peer-reviewed, Open Access journal aiming to provide a platform for the dissemination of research results on regeneration and tissue repair across phy...

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Happy to share my first preprint as senior author! Our great PhD student @kimjuli.bsky.social in @beckergroup.bsky.social shows that macrophages are quite dynamic and heterogeneous after spinal cord injury in 🐟 and all express regeneration-relevant genes! Find more in @biorxivpreprint.bsky.social

Diverse origins and transcriptional profiles of macrophages in a spinal lesion in zebrafish

The injury responses of tissue-resident macrophages in the CNS (microglia) and blood-derived macrophages (BDMs) play key roles in successful regeneration of the zebrafish spinal cord, but the origins ...

biorxiv.org

Congratulations to Dr. Markus Westphal and Dr. Rachel Branch from @beckergroup.bsky.social on this cool preprint! They show that spinal cord injury induces a stem-like progenitor state, and that these cells actively signal to their environment!! Find more on @biorxivpreprint.bsky.social

Spinal injury induces a stem cell-like progenitor state that promotes regenerative neurogenesis via clcf1 in zebrafish.

After spinal injury, zebrafish, in contrast to mammals, show regenerative neurogenesis, characterized by enhanced injury-induced proliferation of ependymo-radial glial cells (ERGs) and an increase in ...

biorxiv.org

Very glad to announce that my first postdoc study in @beckergroup.bsky.social has been officially published in @plosbiology.org If you ever wondered how microglia control the production of new neurons and simultaneously promote spinal cord repair, this is your paper. Microglia rule! 🤟🐟

The microglia-derived protein Sema4ab attenuates regenerative neurogenesis after spinal cord injury in zebrafish

Zebrafish can regenerate neurons after spinal cord injury, but the mechanisms influencing this ability remain unknown. This study shows that Sema4ab, a protein expressed in lesion-reactive microglia, attenuates regenerative neurogenesis by directly regulating neural progenitors and altering cytokine signaling in the niche.

journals.plos.org

What are the mechanisms allowing #zebrafish to #regenerate their neurons after spinal cord injury? This study by @albertodseara.bsky.social , Catherine Becker, Thomas Becker &co shows that a protein in #microglia regulates regenerative #neurogenesis in multiple ways 🧪#AcademicSky plos.io/4xy2CcB

Congratulations to our amazing colleague and PhD student Xiaobo Tian which has recently published his first paper from @beckergroup.bsky.social. A very systematic and complete story that helps us better understand how neutrophils contribute to spinal cord regeneration in zebrafish. Don't miss it!

A reparative neutrophil subpopulation accelerates spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4 - Journal of Neuroinflammation

In mammals, a dysregulated immune response is detrimental to spinal cord repair. In zebrafish, which are capable of spinal cord regeneration, the immune response promotes regeneration. Neutrophils are...

link.springer.com

🦈🧠2 JOB OFFERS in the brand-new Neuroshark group starting at the Institute of Neuroscience Paris-Saclay (NeuroPSI)? Lab manager: www.linkedin.com/posts/idoia-... Bioinformatician: www.linkedin.com/posts/idoia-... Curious about the lab but not your profile? Feel free to contact me

Lab manager job | Idoia Quintana Urzainqui

JOB OPPORTUNITY 🦈 🧠 🔬. We are looking for a Lab Manager to help establish a new group studying shark embryos to understand the origin of the vertebrate brain. Reach out if this motivates you. We’re ba...

linkedin.com

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

Induction of menstruation in mice reveals the regulation of menstrual shedding

During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

biorxiv.org

📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors: Alex Hughes and Rashmi Priya 📅 Deadline: 1 March 2026 journals.biologists.com/dev/pages/ex... #DevBio

🥳 Congratulations to our postdoc, Dr. Anna Czarkwiani @aniaczark.bsky.social, on receiving the ERC Starting Grant @erc.europa.eu! With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠 #CMCBnews @tudresden.bsky.social #ERCStG

🧠🧪Funded PhD job offer ok neddylation in glial cells @achucarro.bsky.social Pls repost

🧠🦈Excited to present our latest work🧠🦈Interested in brain evolution? And shark embryos? Then read on… Our work sheds light on the deep origins of our brain’s most complex regions.

Zebrafish larvae are really good for time lapses. Just take some popcorns enjoy them like if they were movies. Here you can see with your own eyes how immune cells divide. This one I call it "Divide and flee" #spinalcordregeneration #zebrafish #timelapse #microglia

Our work on the TET enzymes in retinal development is out. We identified that rod fate is inhibited when DNA demethylation is prevented by removal of the TET enzymes. Interestingly, photoreceptor numbers are normal. We utilized WGBS and bACE-seq to profile the precise localization of 5mC and 5hmC,…

PLOS Biology@plosbiology.org · last yr.

TET enzymes remove #DNAmethylation markers; @ismaelhdeznunez.bsky.social @clark-lab-retina.bsky.social &co show that these enzymes are required for #photoreceptor cells to initiate the genetic program to become rods instead of cones, & for maturation of the #retina @plosbiology.org 🧪 plos.io/3UaVBfl

🚨Anyone want a job?🚨 We have two #postdocs up for grabs! 🧪 - cell developmental biology/#evodevo/#neuroevodevo - bioinformatics and molecular biology Both working on brain evolution in Heliconiini butterflies Details below! Please repost 🙏 1/n

One long standing question answered ✅ Beautiful science ✅ Cool model organism ✅ Congratulations to the authors!

Leo Otsuki@leootsuki.bsky.social · last yr.

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14

Useful tips from @scekker.bsky.social et al. 🐟

Communications Biology@commsbio.nature.com · last yr.

A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental rigor and reproducibility. www.nature.com/articles/s42...

African turquoise killifish are short-lived & their CNS exhibits human-like ageing. Zandecki @eveseuntjens.bsky.social & co reveal the cellular diversity during the explosive growth of the telencephalon, uncovering specific progenitor signatures for each neurogenic region. 🧠 doi.org/10.1242/bio....

🫀Job alert 🧬 come and be our colleague! Join a BBSRC-funded consortium aiming to understand how the human heart develops - you will be contributing multimodal single cell & spatial transcriptomics data using zebrafish and human cardiac organoids as models. Learn more: www.heartdevelopment.org (1/4)

CellTalk HHD | Human Heart Development Research

CellTalk-Human Heart Development is a BBSRC funded consortium established to find out more about how cells come together to build the heart as it grows inside the womb.

heartdevelopment.org

Are you interested in how cells talk to each other to promote regeneration in the heart? @bailinwu.bsky.social @florian-constanty.bsky.social and I are and we wrote a review about it ❤️🐟🐭 Check it out here 👇 www.sciencedirect.com/science/arti...

Cardiac regeneration: Unraveling the complex network of intercellular crosstalk

The heart is composed of multiple cell types, including cardiomyocytes, endothelial/endocardial cells, fibroblasts, resident immune cells and epicardi…

sciencedirect.com

Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina. @tomreh.bsky.social Marina Pavlou. #retina #regeneration @uwmedicine.bsky.social shorturl.at/qVUKz

Regenerating Retinal Neurons using AAV Vectors / ISCRM

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shorturl.at

This afternoon 👇🏻

International Society for Regenerative Biology@isrbio.bsky.social · last yr.

Happening Today!🚨ISRB Webinar Alert - Zone 2: Europe, West Asia, Africa 📷 Join us on May 13th at 4pm Central European Time. Featuring @albertodseara.bsky.social

Now you can also read all about @idoiaeu.bsky.social beautiful work on catshark brain development and the enigmatic origin of cajal retzius cells in their preprint www.biorxiv.org/content/10.1...

Developmental landscape of shark telencephalon sheds light on the evolution of telencephalic cell types and the ancient origin of Cajal-Retzius cells

The emergence of predation and associated complex behaviors in jawed vertebrates (gnathostomes) have been major driving forces in brain evolution. To gain insight into the neuronal complexity of the l...

biorxiv.org

katja heuer@k4tj4.bsky.social · last yr.

Modern sharks as our best mirror to our jawed common ancestor – @idoiaeu.bsky.social talks about the catshark embryo as a model to study the origin and evolution of the vertebrate telencephalon at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Excited to share our preprint! We show that sustained macrophage and B cell responses are essential for heart regeneration in Mexican cavefish, helping uncover why surface fish heal but cavefish scar 🫀🐟. Check out the full story: www.biorxiv.org/content/10.1...

Absence of a prolonged macrophage and B cell response inhibits heart regeneration in the Mexican cavefish

A balanced immune response after cardiac injury is crucial to successful heart regeneration, but knowledge of what distinguishes a regenerative from a scarring response is still limited. The Mexican c...

biorxiv.org

The next 13th of May I’ll be taking about microglia in spinal cord regeneration. If you’re interested 👇🏻👇🏻

International Society for Regenerative Biology@isrbio.bsky.social · last yr.

🚨ISRB Webinar Alert - Zone 2: Europe, West Asia, Africa 📷 Join us on May 13th at 4pm Central European Time. Featuring Alberto Docampo Seara.

Exacerbated sonic hedgehog signalling promotes a transition from chemical pre-patterning of chicken reticulate scales to mechanical skin folding: royalsocietypublishing.org/doi/10.1098/... @lanevol.bsky.social‬ @rorylcooper.bsky.social‬ #OpenBiology #DevBio #biophysics

Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇

Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration

Nature Communications - Adult zebrafish are capable of heart regeneration, but how the collagenous injury site is replaced remains unclear. Here they provide an in-depth analysis of cardiomyocyte...

rdcu.be