Guys! @jbahler.bsky.social and I are recruiting a PhD student in this round - if you know great undergrads or Masters students please tell them about us! And Crick in general, of course ;) Thank you!!

The Francis Crick Institute@crick.ac.uk · 7d ago

PhD recruitment is now open at the Crick, and we're looking for people to join a community of researchers tackling big scientific questions in the heart of London. Apply by 3 November: www.crick.ac.uk/careers-and-... Find out more about the three routes into our 2027 PhD programme in this thread ⬇️

UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....

Quantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell Biology

Lennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ...

nature.com

Ahh a hot topic 🤗

Jez Carlton@jezcarlton.bsky.social · last wk.

Hey! Submit your papers, and spread the word, this will be great! Thanks for inviting us @jcellsci.bsky.social and great to work with @pihanson.bsky.social on this issue!

People!!! This workshop will be ACE - please share, please apply!

The Company of Biologists@biologists.bsky.social · 2w ago

Applications are now open for early-career researchers to apply for a funded place at our Workshop on Membrane Function: Insights from Cellular Diversity and Evolution, organised by Snezhana Oliferenko @alebenoit.bsky.social & Cunqi Ye. Find out more and apply www.biologists.com/workshops/ju...

*JobAlert* One more week to apply for a post-doc position in my lab at Dundee to study co-translational protein quality control of secretory and membrane proteins. This is a collaborative project with @kulathu.bsky.social and @zeqiraj.bsky.social www.jobs.ac.uk/job/DSM201/p...

Postdoctoral Research Assistant - UOD2336 at University of Dundee

Discover an exciting academic career path as a Postdoctoral Research Assistant - UOD2336 at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

jobs.ac.uk

Treat biological databases as infrastructure, not projects www.nature.com/articles/d41... We're quietly defunding the infrastructure modern biology runs on. PomBase, FlyBase, HGNC. have faced, or facing, existential funding crises since 2024. Curation expertise, once lost, is difficult to rebuild.

So CUTE

Bungo Akiyoshi@bungoakiyoshi.bsky.social · 2mo ago

Now accepted in Journal of Cell Science @jcellsci.bsky.social doi.org/10.1242/jcs....

Not the Moon!

Read about our latest work here www.cell.com/cell/fulltex... or let Alessandro tell you all about it (link below)!

The sex and reproductive plasticity of intestinal muscles instruct gut size

Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls ...

cell.com

The Francis Crick Institute@crick.ac.uk · 2mo ago

“I believe my findings are just the tip of a bigger iceberg.” Read more about the work from Alessandro, a postdoc in our Organ Development and Physiology Lab led by @irenemiguel-aliaga.bsky.social, who studied changes in the female intestine during and after reproduction: https://bit.ly/4bElX2u

Endocytic clathrin coats are surprisingly dynamic: triskelia turn over in seconds. How is the turnover regulated and what is it for? Read Anne-Laure Boinet's preprint with @rouxlab.bsky.social www.biorxiv.org/content/10.6...

We are excited by the publication of our work on Torsin1A, its interaction partner CLCC1, and their role in membrane fusion during NPC biogenesis! A fantastic collaboration with @jagannathan-lab.bsky.social @labvanni.bsky.social @gautamdey.bsky.social and the Korkhov and Antonin labs!

The dystonia-associated Torsin1A sustains CLCC1 function in membrane fusion of the nuclear envelope for NPC biogenesis

Maslennikova et al. identify the ER membrane protein CLCC1 as an interaction partner of the dystonia-linked AAA+ ATPase Torsin1A. Torsin1A sustains the function of CLCC1, which is proposed to facilitate fusion of the nuclear envelope during NPC biogenesis by forming an oligomer that promotes lipid bilayer approach and remodeling.

cell.com

Brilliant Elisa!!!

King's Faculty of Life Sciences & Medicine@kingslsm.bsky.social · 2mo ago

Dr Elisa Gomez Gil is a postdoctoral researcher @kingscollegelondon.bsky.social @crick.ac.uk. We spoke to Elisa to find out more about her recent paper in Genes & Development, her love for sport and cooking, and her hopes for the future: www.kcl.ac.uk/5-minutes-wi... @alebenoit.bsky.social

Published!!! Homeostatic fun!!! Given it’s homeostatic perhaps should go for one exclamation mark! genesdev.cshlp.org/content/earl...

Ahh the prettiest story 𑣲₍ ᐢ. .ᐢ₎

@vjesticalab.bsky.social · 3mo ago

Why did the two gametes (egg♀️ and sperm♂️) start to become different? It's a strategy to optimize the costs and benefits of investing into offspring! Read our brand new @pnas.org story that finds a molecular mechanism behind this evolutionary idea proposed in 1972 by Parker, Bell and Smith.

Awww what fun! www.nature.com/articles/s41...

Outsourcing of energetically costly amino acids at the origin of animals - Nature Communications

Animals must obtain half of their amino acids from the diet, influencing their evolution and metabolism. This study suggests that energy pressures favored this outsourcing, enabling proteins to evolve...

nature.com

Very excited that our discovery of Sms1 as the #MAPK #scaffold of fission yeast mating has just been published in @natcomms.nature.com! @biology-unige.bsky.social www.nature.com/articles/s41...

ASCB @ascbiology.bsky.social and EMBO @embo.org communities - Snezhka @alebenoit.bsky.social and I are Co-Chairs of the CellBio 2026 program committee. Please share that June 9th is the standard abstract deadline - earlier than in the past. Please submit an abstract and join us in San Diego!

What! www.nature.com/articles/s41...

@gautamdey.bsky.social, @fritzlaylin.bsky.social, @alebenoit.bsky.social and @eelcotromer.bsky.social discuss how the field of evolutionary cell biology works to understand how cells evolve & diversify, highlighting current challenges & the future outlook. journals.biologists.com/jcs/article/...

Super-fun, absolutely WONDERFUL paper from Gohta Goshima www.nature.com/articles/s41...

Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! 🧪

Wild and amazeballs

Luiz Pedro Carvalho, PhD@luizcarvalholab.bsky.social · 10mo ago

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.

Fission yeasts lookup

two south park characters are looking at a red car with a magnifying glass

ALT: two south park characters are looking at a red car with a magnifying glass

media.tenor.com

liti_nice@litinice.bsky.social · 10mo ago

here is our first contribution of yeast in microbiomes led by Jason Tsai group[ with contributions from Alberto and Nelly: www.biorxiv.org/content/10.6... more to come

Yay - and also thank you to the three reviewers! /)/) ( . .) ( づ♡

Gautam Dey@gautamdey.bsky.social · 10mo ago

Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍 W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social journals.biologists.com/jcs/article/...

If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X

Homeostasis! Membranes! Evolution! Yay

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 11mo ago

Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes https://www.biorxiv.org/content/10.1101/2025.11.06.686945v1

Ahhh CUTE!!!

Buzz Baum@buzzbaum.bsky.social · 11mo ago

We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.

Minimal CDK continues delivering 💥 www.biorxiv.org/content/10.1...

Regulation of cell proliferation by a novel feedback system on Cdk function

The proliferation of eukaryotic cells is regulated by a complex network of regulatory systems that promotes efficient cell cycle progression and ensures proper responses to the environment. Despite th...

biorxiv.org

Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...

Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules - Nature Communications

Systematic discovery of proteins interacting with low-abundance RNAs is challenging. Here, the authors develop an enhanced HyPro technology to identify proteins associated with compact RNA compartment...

nature.com

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction! Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1 doi.org/10.1101/2025...