PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs

Cilia alert! Last year Juyeon Hong described a new domain in 9+2 cilia called the EDT, the extreme distal tip. Now, she's found a new protein required for its assembly, but only in non-mammalian vertebrates. A cool evo-cell / protein evolution story in @cellreports.bsky.social tinyurl.com/2xvdskx6

Great Stuff from Scotty & crew!

@tafesselab.bsky.social · yesterday

To understand what a lipid does, we need to know its partners. Which proteins bind lipids and how can we capture those interactions? Our new Nature Protocols paper provides a practical, step-by-step guide to identifying lipid-binding proteins. 🧵

Take a look at our new paper on the structure of the EHD2 that, upon oligomerization, forms rings that remodel the plasma membrane and form caveolae. Beautiful work by Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff & Oliver Dumke's team; take a look: www.nature.com/articles/s41...

Job alert! I'm recruiting a new post-doc to work on mechanisms of co-translational quality control in the ER. Looking for expertise in ribosome biology and yeast genetics/cell biology. Please reach out to me with any questions. www.dundee.ac.uk/work-for-us/...

Postdoctoral Research Assistant - UOD2336

Closing date: Thursday 27 August 2026, 23:59

dundee.ac.uk

New in @embojournal.org: Polo/PLK1 phosphorylation relieves Cnn autoinhibition to drive centrosome scaffold assembly. Human CDK5RAP2 appears to share the fly-like mechanism.

Polo/PLK1 phosphorylation relieves Centrosomin/Cnn autoinhibition to promote centrosome scaffold assembly - The EMBO Journal

Mitotic centrosome maturation requires Polo/PLK1-dependent expansion of the pericentriolar material (PCM). In Drosophila, Centrosomin (Cnn) assembles a scaffold around mitotic centrioles through inter...

link.springer.com

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

New preprint! How does a cell "know" how big to make its nucleus? This has puzzled biologists since the 1800’s. We show the answer is physics: colloid osmotic pressure. 🧵1/5

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 2w ago

Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelope https://www.biorxiv.org/content/10.64898/2026.07.21.739918v1

The second July issue is online: link.springer.com/journal/4431... The cover features work by Naoyuki Inagaki, Kio Yagami and colleagues from NAIST describing spontaneous membrane protrusion and cell morphogenesis via self-propelled #actin filaments. -> link.springer.com/article/10.1...

Delighted to see this published! 🎉 Why do cells invest in such tight control of tubulin synthesis? @ac-almeida.bsky.social shows that even small increases in tubulin levels alter microtubule dynamics and disrupt multicellular architecture and viability. Bravo to the whole team 👏! 👉 rdcu.be/fu8ek

Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability

Nature Communications - Almeida AC et al. uncover the physiological role of a long-elusive feedback pathway that regulates tubulin biosynthesis. By tuning microtubule dynamics, this mechanism...

rdcu.be

Ana Coelho Almeida@ac-almeida.bsky.social · 2w ago

Hot off the press!! 🚨 Our work is now published in #NatureCommunications! We show that keeping tubulin levels in check is key for preserving microtubule dynamics, multicellular architecture and viability. A huge thank you to the @ivanagasic.bsky.social team for making this possible! 🙌 rdcu.be/fu8ek

One of the biggest surprises from our new study! When we depleted SGEF, epithelial cysts didn't simply lose normal lumen architecture, they became motile, fused with neighboring cysts, and developed enlarged multi-lumen structures.

Apparently the "boring billion" was actually exciting! We provide molecular evidence of complex Mesoproterozoic eukaryotic communities. So happy to see this out 🥳 Thanks to @phoebefossil.bsky.social , Hélène Morlon & @fburki.bsky.social for a lovely collab! doi.org/10.1073/pnas...

🚨 Want to start your lab in Marseille on a broad neuronal/brain development theme? There's an exciting tenure track opportunity at @inp-marseille.bsky.social and others Marseille institutes! Check more details here: neuro-marseille.org/en/blog/juni... or contact me if you have any question

This is a fantastic opportunity, I started my lab through this scheme and the support throughout is phenomenal, please share.

The Dunn School, Oxford@dunnschool.bsky.social · 3w ago

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...

I am starting my lab at the University of Geneva next January! Incredibly excited to soon be joining the MOCEL department as an Asst. Professor. The lab will use evolutionary cell biology to study chromosomes, centromeres & speciation 🧬🔬🌱 Intrigued, want to join or collaborate? 🔗 helsenlab.org

Helsen lab | chromosome and centromere evolution

The Helsen lab at the University of Geneva explores how centromeres and chromosomes evolve, diversify, and function across eukaryotes. Discover our latest publications, research team, and open positio...

helsenlab.org

ESCRTs are repurposed when missegregated DNA persist during nuclear envelope reformation, at this point ESCRT-III binds this DNA and mounts the NoCut response to protect the genome

Juan Martin Serrano@juanmartin-serrano.bsky.social · 3w ago

Very proud to see this paper out. This is an incredible collaboration with the labs of Wes Sundquist and Adam Frost. @uofubiochem.bsky.social @kingslsm.bsky.social www.nature.com/articles/s41...

Team science preprint, exploring the capabilities and limitations of Alphafold3 across different application areas, including protein-RNA, protein-lipid, ubiquitination,TCR and antibody recognition with @ninjani.bsky.social @labvanni.bsky.social @dgfeller.bsky.social www.biorxiv.org/content/10.6...

Capabilities, specificity gaps and training-data dependence of AlphaFold3 across diverse application areas

Structure prediction models have moved from single proteins to assemblies that include diverse biomolecules and their modifications. AlphaFold3 (AF3) and related models extended structural modelling v...

biorxiv.org

Can we program a kinase like a switch? Inspired by natural autoinhibitory complexes, we designed miniproteins against active- and inactive-like conformations of Focal Adhesion Kinase. Depending on the targeted state, the resulting binders either activated or inhibited the kinase.

Membrane Contact Sites in Cellular Homeostasis 📅 28–30 Sept 2026 | Chepstow, Wales Latest development in membrane contact site formation, remodelling and function Early booking deadline: 28 July 2026 👇 www.eventsforce.net/biochemsoc/f...

New paper from the @xionglab.bsky.social and Mogessie labs at Yale! We uncover the molecular architecture of mammalian oocyte cytoplasmic lattices (CPLs), revealing GTP-bound tubulin associated with a degradative protein complex. Read the paper: doi.org/10.1038/s415...

Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs - Nature Structural & Molecular Biology

Li et al. obtain high-resolution, native structures revealing that cytoplasmic lattices in mammalian eggs organize and store degradative and cytoskeletal complexes for early embryonic development.

doi.org

Not everyday a friend is able to define a new organelle!!! If you like membrane compartimentalization and are interested in how cells responde to stress in membrane tension, check this out!👇👇 Congrats to Elda and co!! www.biorxiv.org/content/10.6...

We are hiring! Join the fantastic Structural Biology, Biochemistry and Biophysics team at Nature Communications. More information here: springernature.wd3.myworkdayjobs.com/SpringerNatu...

Associate or Senior Editor, Nature Communications (Structural Biology, Biochemistry, or Biophysics)

Job Title: Associate or Senior Editor Locations: Pune, Shanghai, Beijing Application Deadline: 31st July'26 About Springer Nature Springer Nature is one of the leading publishers of research in the wo...

springernature.wd3.myworkdayjobs.com

Excited to share our new paper, now published in Nature Cell Biology! 🎉 We asked a fundamental question in cell biology: How do cells maintain polarity while migrating? Especially how do cancer cells navigate confined spaces? www.nature.com/articles/s41556-026-01981-1

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration - Nature Cell Biology

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

nature.com

Exciting preprint from @hessofarhan.bsky.social! Mechanical stress has a new sensor! IRE1 detects ER membrane tension and drives protein synthesis independently of its canonical UPR role, reshaping cell and organelle mechanobiology. www.researchsquare.com/article/rs-1...

Why did the two gametes (egg♀️ and sperm♂️) start to become different? It's a strategy to optimize the costs and benefits of investing into offspring! Read our brand new @pnas.org story that finds a molecular mechanism behind this evolutionary idea proposed in 1972 by Parker, Bell and Smith.

Meiotic cohesin Rec8 imposes fitness costs on fission yeast gametes favoring the evolution of parental bias in gene expression | PNAS

Differences between partner gametes, which evolved repeatedly in eukaryotes, can contribute to the evolution of the sexes, sexual selection, and no...

doi.org

An evolutionarily conserved, short linear actin filament-binding motif (SFM), present in >100 proteins. Great collaboration with the Windhorst and Marlovits labs. Happy to have contributed, by using macrophage podosomes as a readout. Publication in Nat Cell Biol: www.nature.com/articles/s41...

My department @eth-dbiol.bsky.social at ETH Zurich is hiring for a tenured professor in mol cell bio and biochemistry (associate/full). The position is within the Institute of Biochemistry (www.bc.biol.ethz.ch) and it is fairly open within their scope of research. www.nature.com/naturecareer...

Professor of Molecular Cell Biology and Biochemistry - Zurich, Switzerland job with ETH Zurich | 12861386

The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry

nature.com

We are recruiting a lab manager for my group in Oxford. This is a lovely team doing great things, and you could be an important part of it! See here: www.path.ox.ac.uk/vacancy/lab-... Please spread the word!

Lab Manager - Molecular Immunology - Dunn School

Laboratory Manager/Senior Scientist position in the Molecular Mucosal Immunology group at Oxford

path.ox.ac.uk

Excited to share our new preprint! The derlin Dfm1 promotes Ste24-dependent translocon quality control! I'm so proud of the many master's, undergrad, & high school students who contributed to this project over many yrs. Very grateful to collab w/ Robb Tomko! (1/4) www.biorxiv.org/content/10.6...

Dfm1 promotes Ste24-dependent translocon quality control

Proteins stalled during endoplasmic reticulum translocation clog Sec61 channels and require translocon quality control (TQC) mechanisms for clearance. Genetic screens implicated the derlin Dfm1 in TQC...

biorxiv.org

Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩‍🔬👨‍🔬

Biozentrum, University of Basel@biozentrum.unibas.ch · last mo.

New Assistant (tenure-track) or Associate Professor position in Climate #Biophysics! Join our international research community to explore fundamental molecular mechanisms underlying climate-relevant biological processes. Apply by 7 Sept 2026! www.biozentrum.unibas.ch/de/open-posi...