ICYMI: New Online! Tight junction structure, assembly and (dys)function

Tight junction structure, assembly and (dys)function

Nature Reviews Molecular Cell Biology, Published online: 03 June 2026; doi:10.1038/s41580-026-00978-wTight junctions form essential paracellular barriers and regulate cell polarity and tissue mechanics. This Review discusses how tight junction components assemble into strand networks, and explores tight junction function in development and disease, and emerging therapeutic strategies.

dlvr.it

Interested in caveole and/or lipid metabolism? We have two master thesis projects available in the lab @unipotsdam.bsky.social starting September or October. For more details 👇 www.matthaeus-lab.de/post/04-2026...

Lipid-CLEM by @mathilda95.bsky.social on the Cover of @natcellbio.nature.com! Link to article: www.nature.com/articles/s41...

🍰Read also the News & Views article written by Aubrey Weigel: 👉https://rdcu.be/fdcf4 bit.ly/4tNdLn9

Now out in its final form in @jacs.acspublications.org: Reaction pathways & photoreaction yields of bifunctional lipid probes. The numbers that explain why we spend so much time optimizing protocols for cellular assays. 😉 pubs.acs.org/doi/10.1021/...

Bifunctional Lipid–Protein Cross-linking Efficiency and Reaction Products

Bifunctional diazirine lipids are versatile tools for mapping protein–lipid interactions and cellular localization by photo-cross-linking. Yet, the cross-linking efficiency of these probes has not bee...

pubs.acs.org

André Nadler@nadlerlab.bsky.social · 6mo ago

It's always important to carefully characterize the reactivity of your favorite tools to optimize applications. We teamed up with Carla Kirschbaum and Carol V. Robinson to map photolysis reaction pathways of bifunctional lipids www.biorxiv.org/content/10.6...

We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!

Postdoctoral researcher @isaacsiuwong.bsky.social in the @hymanlab.bsky.social @mpi-cbg.de is 2026 Grass Fellow @grassfoundation.bsky.social @mblscience.bsky.social. 🎉 He will pursue his project “Dancing diatoms as a proto-neural model” at MBL for 14 weeks. www.mpi-cbg.de/news-outreac...

Isaac Siu-Shing Wong is MBL 2026 Grass Fellow

MPI-CBG postdoctoral researcher joins Marine Biological Laboratory, working in the Grass Laboratory for research project.

mpi-cbg.de

Looks like a great @embo.org workshop coming in September: “Lipid Code to Life”, with a who’s who of lipid #biochemistry… (e.g. @dimovalab.bsky.social @holthuislab.bsky.social @sciezgin.bsky.social etc ) More info and registration: meetings.embo.org/event/26-lip... #lipids #biophysics

Busy lipids in nano hotspots: a team with @mathilda95.bsky.social, @nadlerlab.bsky.social & Ori Avinoam @weizmanninstitute.bsky.social developed Lipid-CLEM - an imaging technique to make lipids in cellular membranes visible & show how they are organized at nanoscale. www.mpi-cbg.de/news-outreac...

Busy lipids in nano hotspots

International research team presents new imaging technique to make lipids in cellular membranes visible and show how they are organized at the nanoscale.

mpi-cbg.de

I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you: www.nature.com/articles/s41...

Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology

Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...

nature.com

This is amazing! My mind is boggled. Congrats to the whole team.

Yamuna Krishnan@krishnanyamuna.bsky.social · 8mo ago

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Janelia is hiring! "Invent new imaging methods, molecular tools, or protein chemistry approaches" www.janelia.org/content/lead...

Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...

Finally out! This is an amazing story on lipid trafficking and how to visualize membrane lipids inside of cells! Check it out. I am honored I could contribute a little to this story 😁

André Nadler@nadlerlab.bsky.social · 12mo ago

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...

We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on www.epfl.ch/labs/gr-schu...

Open positions

GR-SCHUHMACHER

epfl.ch

Hello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost! jobs.unige.ch/www/wd_porta...

I am really excited that the second story of my PhD work is on biorxiv now. If you are into lipids, membrane trafficking and super resolution microscopy check it out! Big shout out also to our collaborators, the Honigmann lab and Modes lab.

André Nadler@nadlerlab.bsky.social · last yr.

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...