Check out our new paper! We found general chronic pain is genetically linked to broad addiction liability, while musculoskeletal pain shows more substance-specific genetic associations, particularly with tobacco and alcohol use. Link: onlinelibrary.wiley.com/share/author...

1/4 Thrilled to be sharing new work published today in Nature describing the third wave of results from the PGC Cross-Disorder Group. This reflects a massive group effort to examine shared and unique genetic signal across >1 million cases for 14 psychiatric disorders. www.nature.com/articles/s41...

Mapping the genetic landscape across 14 psychiatric disorders - Nature

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...

nature.com

The Drain of Scientific Publishing arxiv.org/abs/2511.04820

Definitely D. Almost all of middle, south, and Eastern Asia is in there. Even southern Italy!

Brilliant Maps@brilliantmaps.bsky.social · 11mo ago

For the rest of your life, you can only eat food from one of these regions. Which do you choose? For more maps: brilliantmaps.beehiiv.com/s...

For the rest of your life, you can only eat food from one of these regions. Which do you choose? For more maps: brilliantmaps.beehiiv.com/s...

We lay out three consensuses from the field of psychiatric genetics that should be considered before approving genetic tests for psychiatric disorders. The letter was signed by 140 experts in psychiatric genetics and published in Lancet Psychiatry. Now on Pubmed: pmc.ncbi.nlm.nih.gov/articles/PMC...

Concerns About Genetic Risk Testing for Opioid Use Disorder

pmc.ncbi.nlm.nih.gov

Collecting large genome-wide samples may de-risk reinvestment in psychopharmaceuticals. Expanding on past work that lumped all psychiatric disorders together, we conducted a test of the utility of GWAS for specific psychiatric indications. www.nature.com/articles/s43...

Psychiatric genome-wide association study enrichment shows promise for future psychopharmaceutical discoveries - Communications Medicine

Hatoum et al. undertake exploratory analysis of genome-wide association studies of specific psychiatric disorders to find existing medications that treat those disorders and genetic pathways that may ...

nature.com

Casey Means? Sounds pretty average to me *nudge*.

My mandalorian friend asked me which protein powder I use and I told him “this is the whey”. Happy #MayTheFourth

“Er, my question is really in two parts…” From the new Private Eye, out now.

Getting the message out on how science funding benefits our society @abepalmer.bsky.social in the SD Tribune www.sandiegouniontribune.com/2025/03/09/g...

Guest Commentary: Medical research saves lives and helps our community. It deserves the funding it gets

Abraham Palmer, a La Jolla resident and psychiatry professor at UC San Diego, objects to cuts in funding for work that fights diseases

sandiegouniontribune.com

The BEAR Lab will be opening it's doors in July at the Medical College of Wisconsin, and we are looking for our first Research Tech! This position will help with funded MRI studies looking at the brain and alcohol use. More info: bearlab.science/contact/ #neuroscience #psychology #sciencejobs

Contact

We are actively recruiting a Research Technologist! (start date ~7/1/25) Job ad is coming soon. This position will primarily assist with funded studies examining brain function in people who drink …

bearlab.science

So where does the AI race end? Space race was the moon. AI..also the moon?

The Ripke lab has worked on a new stable release of RICOPILI! Updates include compatibility with GRCh38 and imputation using Minimac4. A software tarball and YAML file are provided to help resolve dependency issues: github.com/Ripkelab/ric... Any feedback is highly welcome! @pgcgenetics.bsky.social

GitHub - Ripkelab/ricopili: Main ricopili repo for public releases

Main ricopili repo for public releases. Contribute to Ripkelab/ricopili development by creating an account on GitHub.

github.com

Spoke at the Missouri @standupforscience.bsky.social this morning. Good to get out of the lab and affirm core values.

Out today, our method for comparing multivariate genetic architecture across groups of people, called Genomic Structural Invariance: www.nature.com/articles/s41... (feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)

Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex - Nature Genetics

Genomic structural invariance, an extension of genomic structural equation modeling, identifies similarities and differences between males and females in the genetic architectures of eight psychiatric...

nature.com