Late in sharing, but big congrats to our postdoc Dunja Al-Nuaimi who recieved the Seal of Excellence Postdoc Fellowship from ÖAW 🎉, supporting SELFORM3, a project exploring how self-organizing tissues integrate Mechanics, Matrix, and Metabolism during development. #Mechanobiology #ECM #Metabolism
Abdel Rahman Abdel Fattah
@ar-abdelfattah.bsky.social
Principal Investigator - CeMM Research Center for Molecular Medicine Bioengineer - We use tools to investigate ECM-metabolic-morphogenesis interplay to explore how tissues initiate, maintain and lose organization
🫀🧲Master's Thesis @ Abdel Fattah Lab (CeMM) and Mendjan Lab (IMBA), Vienna Develop next-generation human cardiac #organoids (cardioids) with magnetic bioprinting. Seeking students with a passion for interdisciplinary research/ #Bioengineering. Apply here: cemm.onlyfy.jobs/en/job/iy0ni...
A fantastic talk by Toshiro Sato right here at @cemm.oeaw.ac.at!
🧬 Great #CeMMinar with Toshiro Sato (Keio University) on how regenerative mechanisms can guide next-gen organoid systems, linking tissue repair, cellular plasticity & cancer biology. Thank you, Toshiro, & hosts Georg Busslinger, @bocklab.bsky.social & @ar-abdelfattah.bsky.social! 👏
🚀 #𝗙𝗿𝗼𝗻𝘁𝗥𝗼𝘄𝗦𝗰𝗶𝗲𝗻𝗰𝗲: 𝗮 𝗻𝗲𝘄 𝘀𝗽𝗼𝘁𝗹𝗶𝗴𝗵𝘁 𝗳𝗿𝗼𝗺 𝗼𝘂𝗿 #𝗖𝗲𝗠𝗠𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗥𝗲𝗽𝗼𝗿𝘁𝟮𝟬𝟮𝟱! We continue our focus on disease model systems with two CeMM groups: @ar-abdelfattah.bsky.social & Georg Busslinger 🧵👇
🧠 @ar-abdelfattah.bsky.social’s group develops bioengineering tools to study how mechanical forces shape tissue organization. "We are also studying how excessive forces cause tissue disorganization, like that seen in traumatic brain injuries," he said at the 𝘛𝘩𝘦𝘢𝘵𝘦𝘳 𝘥𝘦𝘳 𝘑𝘶𝘨𝘦𝘯𝘥. 👉 bit.ly/4dYxvQ4
Join us🚨! We’re looking for an ambitious Master’s student to join our Multiscale #Mechanobiology & #Bioengineering Lab at CeMM (Vienna) for a 9–12m #microfluidics project on #engineering the neurovascular unit in #TBI🧠 Lab: abdelfattahlab.org Apply: cemm.at/join-cemm/op...
Big congrats to our Dunja Al-Nuaimi on receiving the highly competitive APART-MINT fellowship from the Austrian Academy of Sciences (ÖAW)! 🎉 She’ll lead the bioengineering of new microfluidic chips to study neuro-vascular interactions during traumatic injuries. Well deserved!
What an incredible #cellmech2025 packed with science, ideas, and inspiration! 🚀 We loved sharing our work on ECM dynamics, mechanics & energy consumption in early development (Dunja Al-Nuaimi & Sowmya Sunkara). Grateful for this vibrant community ➡️ see you at CellMech 2027!
#BloodBrainBarrier "microglia are not necessary for the maintenance of BBB structure, function, or gene expression in the healthy brain" Evidence from >95% microglia depletion by PLX5622, a CSF1R inhibitor (1 mo) & BBB ultrastructure @cprofaci.bsky.social #Neuron 2024 www.cell.com/neuron/fullt...
🚨Preprint alert!🚨 Very happy that our lab could contribute to this new aging story by the @lderooij.bsky.social group, building a Human Aging Atlas with over 375,000 profiled endothelial cells, so many insights including a mechanical twist to our aging endothelium.
🚨Preprint alert!🚨What happens to our blood vessels as we age? To begin answering this at the transcriptome level, we built the Human Aging Endothelial Cell Atlas (HAECA), profiling >375,000 endothelial cells from 12 tissues across adulthood. www.biorxiv.org/content/10.1... (1/9)
On 7–8 July, CeMM Recess 2025 brought our postdoc community together!👩🔬👨🏾🔬 From scientific talks to bold science pitches, feedback, & evening quiz, a retreat full of ideas & inspiration! Thanks to organisers Barbara Maier, @ar-abdelfattah.bsky.social, @dseruggia.bsky.social, & to all who joined! 👏
🔬 As we near the end of #EquationsForLife, today we spotlight @ar-abdelfattah.bsky.social's Group! They use the #ReactionDiffussion equation to characterize the process of tissue organization and maintenance in physiology, and how disease disrupts it. 🔎 bit.ly/4ef2Pbe
What’s the link between Origami and morphogenesis? This is the world of Actuation, I’m @ar-abdelfattah.bsky.social, and I’ll share with you insights, experiments and an outlook on how epithelia use mechanical forces to gain geometrical and functional complexity.
very nice and comprehensive. methods to assess tissue stress. thanks for compiling this.
Tissues are dynamic and investigating cellular mechanical states can be crucial for understanding biological processes. But how to do it? We are @andreasschoenit.bsky.social and @luanger.bsky.social from @bladoux.bsky.social / @rmmege.bsky.social lab highlighting ways to assess tissue stresses.
a very important tool for #ECMatrix enthusiasts!! I'm sure this will come in handy for many researchers.
Our manuscript describing #MatriCom, a web application we developed in collaboration with @valerioizzi.bsky.social to infer #ECM communication systems from #scRNASeq datasets is now available on @biorxivpreprint.bsky.social!
A very informative thread on this emerging field, the metabolic dimension of #mechanobiology!! nicely done.
How is metabolism interconnected with cellular dynamics? We are @emaniou.bsky.social and @hpscenthusiast.bsky.social and through an energy inexpensive process, we will highlight advances in mechano-metabolism and related fields. @epimechfc.bsky.social
Our #TBI project got funded! Driven by what happens when forces are too much to handle, we will engineer tools to traumatize organoids and focus on #ECMatrix dynamics, #mechanobiology, and molecular-to-multicellular tissue organization. Happy to collaborate! Happening @ CeMM
Hi #cancer, #ECMatrix, #biomaterials and #mechanobiology folks: Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇: www.nature.com/articles/s41...
Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option - Nature Cell Biology
Uroz et al. report that the distinct mechanical properties of brain vasculature versus parenchyma drive cancer cell migration through a talin-dependent mechanism, enabling vessel co-option and metasta...
nature.com
👋Hello #mechanobiology community! Next year we are organizing the CellMech conference in Leuven! We will soon be announcing (super amazing) invited speakers, registration deadlines, etc I'll try to keep the🦋community updated, but best is to subscribe to the mailing list 📧👇 cellmech2025.org
Interested in metal transporters, #SLC, metal toxicity? check out the amazing work of Andrè Ferdigg from @supertifurgalab.bsky.social 👇
PhD student @AndreFerdigg and colleagues report in @LSAjournal on #SLC transporters in metal toxicity. MRP1/ABCC1 protects against arsenic and mercury; SLC39A14 and SLC30A1 sensitize for cadmium; interestingly SLC30A1 modulates cadmium toxicity through zinc levels doi.org/10.26508/lsa...
Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...
Mechanobiology across the tree of life
embl.org
If you're interested in magnetic actuation and #mechanobiology, this is a very nice review! 🧲⚙️🧫
Excited to share a new review on Magnets for Mechanobiology - teamed up w/ fellow 🧲 enthusiasts from Boston/Madrid/Zurich/Singapore to share how we manipulate cellular microenvironments w/ magnetic fields! Thanks to @danielgmadrid11.bsky.social for bringing us together! doi.org/10.1002/aisy...
@bioeng-talk.bsky.social is posting here as well! Speaking of moving to new places (🦋), in this episode, a bunch of us discuss why we moved to Europe to continue our academic careers. Tune in to hear about our experiences and what motivated us to make the leap.
For our first post here 🦋, we discuss why some of us changed environments to pursue science, focusing on career moves that brought us to Europe. Are you planning to move for your next position? Hear us about our experiences, motivations, and the hurdles we faced. t.co/5gRHhw2eef
Excited to join the 🦋 community, and even more excited to share that the lab has its very own logo & website! 🖥️🔎 Visit us at derooijlab.org to explore our work, stay updated on ongoing projects, papers, and more!
Let the first post be about our lab website! Happy to announce it's up and running. Our vision of controlling tissue organization and probing its mechanics is rather magnetic 🧲⚙️🧫🧬! #mechanobiology 👉 www.abdelfattahlab.org
Abdel Fattah Lab
abdelfattahlab.org