Andy Radde-Gallwitz
@argphd.bsky.social
Disabled Prof. Long Covid. He/him. Songs written: https://tinyurl.com/5n6zmhm5 “Until we are sick, we understand not.” (Keats) “By reason of my infirmities, I am, . . . like a plant, always held to the same place." (St. Basil)
If you've never heard of ME/CFS, take a moment to learn about it on Severe ME Day.
C.H. Romatowski@chromatowski.bsky.social · yesterdayWish I knew what to say for Severe ME Day. It acknowledges the severe form of ME/CFS, a disease many people still have never heard of even as Covid explodes its prevalence: as many as 9M sufferers in the US alone, a quarter of whom are severely ill—so sick we cannot leave our homes or even our beds.
The combination of this historical neglect and the profound debility of Severe ME make for a scary situation: in desperate need of social solidarity à la breast cancer 5ks or concerts for HIV/AIDS, but instead so sick as to fall out of public view entirely, confined to our homes or beds.
Wish I knew what to say for Severe ME Day. It acknowledges the severe form of ME/CFS, a disease many people still have never heard of even as Covid explodes its prevalence: as many as 9M sufferers in the US alone, a quarter of whom are severely ill—so sick we cannot leave our homes or even our beds.
Updated ME/CFS prevalence estimates reflecting post-COVID increases and associated economic costs and funding implications
In this article, we update our earlier analyses of myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) economic impact and its National Institutes of Health (NIH) funding versus disease b...
tandfonline.com
Hey it’s #SevereMEDay. I have severe ME. The severe category is a ginormous range tho because I’m so much better than I was, and I never felt like I crossed to “very severe” tho I suppose I was on the edge for a bit. I spend most of my time horizontal in bed in a room with the curtains drawn.
It occurred to me, as the friendly nurse was droning on, that none of this was real.
Ah, there it is. COVID seems uniquely suited to waking up the lurking beasts that drive an immune system mad. The virus itself can cause immune dysfunction but it magnifies the effect by waking up its buddies (Epstein Barr and cytomegalovirus). And then "friendly fire" goes amok. #MedSky 🩺
Eric Topol@erictopol.bsky.social · 4d agoSevere Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...
Severe Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...
Virus reactivation in acute and long COVID-19 - Nature
Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...
nature.com
Let me pop back into Professor mode and go over a bit of epistemology for this rando (and sadly many others) who “can’t believe Long Covid is real”: *your* not being able to believe p has no bearing on the truth, or even the plausibility, of p.
Elana Levin@levin.bsky.social · 7d agoLove to have a rando on here basically demanding to see my medical bloodwork results because they can’t believe that long covid is real. This is a proported leftist. There really is a problem and right wing people arent the only ones who are in denial. Have those conversations with people.
Also if you hate living try Long Covid
Melissa Gira Grant@melissagiragrant.com · last wk.if you hated covid "lockdowns" try long covid
New from DelCogliano,Ayres, Crawford, practically the whole gang
Mark DelCogliano@markdelcogliano.bsky.social · last wk.Two years after submission, twenty-two years after conception, it’s published. I believe Sept. 28 is the official publication date in the US. Not sure about the UK and elsewhere. I’ll share a discount code when I receive one.
I am happy to announce the publication of a new English translation of Jacob of Serugh's four homilies on Cain and Abel. It was wonderful to work on this project with Jeff Wickes! The homilies are fascinating theological and literary works: svspress.com/verse-homili...
Verse Homilies on Cain and Abel
Founded in 1968, St Vladimir's Seminary Press is the largest and most active publisher of Orthodox Christian books in the English language.
svspress.com
UCSF latest study Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID Combinatorial tetramer deep-profiling of viral-specific T cells in long COVID (LC) LC features more cytolytic CD8+ T cells against SARS-CoV-2, CMV, and EBV Females with LC
Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID
Ma et al. perform deep-phenotyping of CD8+ T cells specific for viruses implicated in LC pathogenesis: SARS-CoV-2, CMV, and EBV. These T cells from LC individuals share features of terminal differenti...
cell.com
In its fundamental essence, today is a Tuesday, though it wears a hat that says “Sunday.”
Come to think of it (Moby Dick), there is something wrong with a world that will hurt you but not fight you.
It just dawned on me that the area where Moby Dick is killed is more or less the antipode, the spot exactly on the other side of the earth, to Jerusalem.
“When focusing only on patients who tested positive for anti-SITH-1 antibodies, it was confirmed that treatment with donepezil significantly improved measures of fatigue and depression.” mainichi.jp/english/arti...
Dementia drug shows promise for long COVID symptoms, Japan-led study finds - The Mainichi
TOKYO -- A research team led by the Tokyo Jikei University School of Medicine announced that it has identified part of the mechanism underlying fatigu
mainichi.jp
If “anything can be a weapon“ then anyone – everyone – wearing, eating, holding, driving, drinking, cleaning or petting anything can be armed and dangerous. Thus, we’re all eligible for shooting if we do any of those in the direction of the brown shirts hunting brown people.
I remember when these unstaffed chain drug stores were sparking new clean portals to the End of History
My writing recently — poetry and fragments — keeps pulling me into odd, uncomfortable places, so I am very reluctant to share it. It’s just there, slightly terrifying me. But, of course, no turning back now! This is vague and probably dull to anyone else, but I felt due for a small void-scream.
I think the ball has the momentum in this game. It’s physics.
They’re at the game because they symbolize England. Of course if they were real knights they’d be out on a quest. Took me a minute.
JM =^D@jm539581.bsky.social · 4w ago
🧠 What if #LongCovid is, in part, a disorder of dopamine? Our new commentary explores how disrupted dopamine signaling may help explain fatigue, brain fog, and autonomic dysfunction, and what this could mean for future therapies. Open access link: shorturl.at/vLAfU
Chantzy@chantzy.bsky.social · 4w ago"Our findings provide compelling evidence that long COVID involves the loss of dopamine-releasing neurons," says Dr. Jeffrey Meyer, senior scientist at the Brain Health Imaging Center, Canada Research Chair medicalxpress.com/news/2026-07...
“for I cherish the greatest respect towards everybody’s religious obligations, never mind how comical” (Melville)