Disturbed metabolic adaptation drives natural killer cell dysfunction in association with nosocomial infection during human sepsis www.thelancet.com/journals/ebi...

I wanted to thank everyone who I had the opportunity to speak to & learn from with this past week at #RSA2026! I had the opportunity to present my work on how alcohol disrupts the innate immune system during bacterial pulmonary infection. It is always wonderful to represent @unmc.bsky.social!

Nebraska Medicine and UNMC have been asked by federal partners to receive and monitor U.S. citizens from the cruise ship associated with a hantavirus outbreak. These individuals will be observed in the National Quarantine Unit.

Nebraska Medicine/UNMC asked to monitor U.S. citizens from cruise ship hantavirus outbreak

The National Quarantine Unit, located at UNMC, is the only federally funded quarantine unit in the United States.

unmc.edu

A summary of the 2025 Alcohol Immunology Research Interest Group meeting was published in @alcoholjournal.bsky.social! Here I describe a portion of my PhD project: the effect of alcohol use disorder on macrophage metabolism and effector function: www.sciencedirect.com/science/arti... #ImmunoSky 🧪

Effects of Alcohol Use on the Gut, Inflammation, and Organ Injury: A Summary of the 2025 Alcohol and Immunology Research Interest Group (AIRIG) Meeting

The 30th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held on June 21st, 2025, at the Hyatt Regency in New Orleans, Louis…

sciencedirect.com

Fewer grad students means less science, but many STEM PhD programs in the US are cutting back on admissions this year due to federal funding uncertainties. Words by me for @nature.com: www.nature.com/articles/d41... @emsque.bsky.social @ucsdcooperlab.bsky.social @julieposselt.bsky.social 🧪

US PhD admissions shrink as fears over Trump’s cuts take hold

Some doctoral programmes are admitting no students at all amid uncertainty about federal science funding.

nature.com

Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!

Monocyte-specific aryl hydrocarbon receptor deficiency leads to microbiota-mediated tonic cytokine response via STING pathway 🧪 www.jci.org/articles/vie...

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu Apply here apply.interfolio.com/174404

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass... I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands) #WesternBlot #cellsky

Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!

Working on immunometabolism? Or looking for people who do? Then here’s the starter pack for you! 😊 #Immunosky go.bsky.app/MvxkA4Q

A history of alcohol use disorder increases the risk of death from sepsis. Researchers found that the HIF-1α-PFKP axis regulates glycolysis and phagocytosis in ethanol-exposed macrophages and is a potential therapeutic target in ethanol with sepsis: ow.ly/S5AQ50WOgnB.

Mitoquinol improves phagocytosis and glycolysis in ethanol-exposed macrophages via HIF-1α-PFKP axis

Abstract. Alcohol use disorder increases sepsis mortality. Acute ethanol exposure impairs pathogen clearance in the macrophages via dampened glycolysis and

ow.ly

Respiratory viral infections awaken metastatic breast cancer cells in lungs Note: This concerns many infections (inflammation, trauma), including respiratory viruses and is NOT specific for SARS-CoV-2 as some claim. www.nature.com/artic... 1/9

Respiratory viral infections awaken metastatic breast cancer cells in lungs

Nature - Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by...

nature.com

ICYMI:

Species-specific serine metabolism differentially controls natural killer cell functions

Nature Metabolism, Published online: 14 August 2025; doi:10.1038/s42255-025-01348-0Li et al. characterize overlapping and divergent metabolic requirements of human and murine NK cells in response to activation, with a focus on serine metabolism

bit.ly

@unmc.bsky.social SUARP program ended yesterday, and our undergraduate student who was such a pleasure to have with us this summer presented a wonderful poster on how alcohol affects the metabolic capacity of the gut microbiome! See more about his experience here: www.linkedin.com/posts/benjam... 🧪

Five months ago, I shared that I'd be working with Dr. | Benjamin Hoover

Five months ago, I shared that I'd be working with Dr. Derrick Samuelson at the University of Nebraska Medical Center in the Internal Medicine Department as a part of the Summer Undergraduate Research...

linkedin.com

Just submitted my application and working model for my NIH F31 for #BioRenderForGrants! This model has implications not only in alcohol research, but also in various other fields. If we can force cells to “reroute” to a different metabolic pathway, we may be able to restore effector function.

A US Senate committee endorsed maintaining the NIH's structure and increasing its funding by US$400 million, or about 1% go.nature.com/4mg193S

‘Congress has your back’: US senators tell scientists they want to protect NIH budget

Senate budget bill includes small increase for the health-research agency — but faces a long road before being signed into law.

go.nature.com

If you've ever *benefitted* from NIH research (big population), CALL YOUR SENATOR now to let them know. ⏰ Tmrw morning, Senate appropriators will mark up NIH's FY26 budget. Personal examples help. My own case: decades of *sustained* investment in NIH-funded cancer research saved my life.

Dr. David Miller 🏳️‍🌈@davidimiller.bsky.social · 2y ago

1/11 Though it's personal, I’m sharing this analogy if it helps others: In the last few weeks, I’ve been thinking a lot about my past journey with cancer. Years ago, I found out in the worst way. My doctor accidentally released the biopsy results to my online patient portal. 🧵 Thread

HOW COOL IS THIS? Researchers have developed a DENTAL FLOSS that can DELIVER vaccines THROUGH the gums, a method that could one day offer a NEEDLE-FREE alternative for vaccination. This approach effectively stimulated immunity AND provided FULL protection against a lethal strain of influenza. 🧪🧵⬇️

My first review paper got its first citation today! To celebrate, I’m putting it back on everyone’s feed: an overview of the microbiome in allergy, asthma, and occupational lung disease: link.springer.com/article/10.1... #ImmunoSky #MicrobiomeSky #AllergySky 🧪

The Role of the Microbiome in Allergy, Asthma, and Occupational Lung Disease - Current Allergy and Asthma Reports

Purpose of Review The human commensal microbiota is now widely accepted as a key regulator of human health and disease. The composition of the mucosal associated microbiota has been shown to play a cr...

link.springer.com

🚨🚨🚨PUI TT Job Alert!! My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students! We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!

My university has announced a special international graduate fellowship for PhD students whose acceptance at a US university has been rescinded. Check it out: grad.uwo.ca/finances/wes...

US-CAN Doctoral Excellence Award

Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.

grad.uwo.ca

As the US breaks a 3-decade milestone for measles cases in one year, I'm reflecting on my worst timed paper ever. I still stand by the points made here. The world, but one leader, remains ready for the endgame. The resonance of the abdication of US leadership is deafening.

Rubella and measles: The beginning of the endgame

Benchmarks must be established and progress tracked to set a global target and take action

science.org

We’re doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!

Your Neighborhood Scientist@your.neighborhoodscientist.org · last yr.

Happy July 4th! Here at Your Neighborhood Scientist, we’re excited to highlight American patriotism in a way you might not always think about: scientific research. neighborhoodscientist.org/posts/2025/j...

Microbial Tryptophan Metabolism Activates Host Lysosomal Activity to Facilitate Lipid Breakdown and Ameliorate Hepatic Steatosis https://www.biorxiv.org/content/10.1101/2025.06.28.662086v1

Multiomics Approach to Regionally Profile Zinc-Driven Host-Gut Microbiome Interactions in the Intestinal Tract https://www.biorxiv.org/content/10.1101/2025.07.02.662895v1

Human gut bacteria bioaccumulate PFAS in dense cluster aggregates; PFAS levels in gnotobiotic mouse GI tract & feces is microbiota-dependent Via @natmicrobiol.nature.com 🧪 www.nature.com/articles/s41...

Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology

Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...

nature.com

Preprint: PD-L1 ligation on NK cells induces a metabolic shift from glycolysis to fatty acid oxidation, enhancing tumor infiltration and control www.biorxiv.org/content/10.1...

To all US citizens: now is the moment to call both your Senators and your Congressional Rep, tell them to vote NO to this atrocity and let them know you are following their every move and it doesn’t matter if they are D or R just blow up their phones. GO. www.congress.gov/members/map?...

Antonia Juhasz@antoniajuhasz.bsky.social · last yr.

The Republicans are struggling to find the votes to pass Trump's massive budget bill. Senator Kim, in a direct appeal to the public, says, "keep the pressure on. help us spread the word." Public resistance, he insists, is working to stop Trump's "Big Disastrous Bill."

Abx ➡️ ↓ AhR ligands ➡️ microglia activation ➡️ ↑ inflammation Very interesting publication!

Blood Journals Portfolio@bloodjournals.hematology.org · last yr.

Antibiotic treatment in GVHD promotes microglial activation by interfering with AhR signaling. buff.ly/lHm7MwM #hemesky