Interested in working with the JGI and never led a proposal with us? Now is your chance! We are accepting submissions to our New Investigator call for first-time PIs. Deadline to submit is Sept. 9. jointgeno.me/CSPnewPI @berkeleylab.lbl.gov @biosci.lbl.gov

CSP New Investigator Call | Joint Genome Institute

The CSP New Investigator Call is for investigators and research initiatives new to the JGI. Projects must be independent of ongoing JGI proposals, and lead PIs cannot have been lead PI on any previous...

jointgeno.me

A really cool preprint from Joanna Wysocka's lab showing that housekeeping genes use distal enhancers as dosage buffers against TF fluctuations, but only during critical cell fate transitions. Makes so much sense! www.biorxiv.org/content/10.6...

Enhancer buffering protects dosage-sensitive housekeeping genes during vulnerable developmental transitions

Housekeeping genes maintain robust expression across cell types despite dynamic transcription factor fluctuations, yet their haploinsufficiency is associated with many tissue-specific developmental di...

biorxiv.org

Hi everyone, my name is Jack. I'm a SULI summer intern at Berkeley Lab. Over the next several weeks I’ll be creating posts sharing my experiences learning about cool research projects across the Biosciences Area. I hope you enjoy this series as I much as I enjoy making it!

🚨 Registration for VEGA26 is 👏 officially open 👏 🚨 The 5th edition of our Viral EcoGenomics and Applications symposium will be held November 18-19, 2026, on the UC Berkeley campus 🧬 🦠 🔬 🧫 Event website ➡️ jgi.doe.gov/work-with-us... Registration link ➡️ cvent.me/e0RnA0

If it walks like a duck and develops like a duck ... the enhancers might still align to humans 🥚🦆 (chicken, actually, but you get the picture) Fun collaboration led by Stella Kyomen and @marketa-kau.bsky.social at @mpi-evolbio.bsky.social

MPI for Evolutionary Biology@mpi-evolbio.bsky.social · 3mo ago

Facial diversity in birds and mammals doesn’t just come from different signals – but from how cells respond to them. A new study in Science Advances shows evolution acts on both: signal placement and cellular interpretation. More Info: www.evolbio.mpg.de/3879733/news... @marketa-kau.bsky.social

Genome Watch👀 "In search of phage tail-like particiles: nature's versatile nanomachines" highlights the importance of predictive models. 🖥️🧬 Full Story: https://rdcu.be/fgU2m @berkeleylab.lbl.gov @axelvisel.bsky.social @natureportfolio.nature.com

In search of phage tail-like particles: nature’s versatile nanomachines - Nature Reviews Microbiology

This Genome Watch article highlights the importance of predictive models for identifying and characterizing the roles of phage tail-like particles as a tool for bioengineering and biocontrol.

nature.com

JGI @jgi.doe.gov is looking for bold partners with expertise in lab automation 🤖, plant transformation 🌱, AI-supported imaging 🔬, and scalable bioengineering 🧬 Goal: build an automated system to identify, select, and process 10k+ transformed plant calluses/day Details: sam.gov/workspace/co...

📢 Letters of Intent for our Large Scale call, part of our Community Science Program, are due April 9. Projects should leverage systems-based approaches to address biofuel and bioproducts production. 🖥️ 🧬 More info: https://jgi.doe.gov/work-with-us/proposals/community-science-program/large-scale

CSP Large Scale Call | Joint Genome Institute

The Community Science Program Large Scale Call is focused on genomic science projects that address sustainable biofuel and bioproducts production.

jgi.doe.gov

Excited to share my latest work on synthetic biology and host–microbe interactions, now published in Nature Communications! www.nature.com/articles/s41...

CRAGE-RB-PI-seq reveals transcriptional dynamics of plant-associated bacteria during root colonization - Nature Communications

This study reveals how plant-associated bacteria dynamically reprogram gene expression during root colonization, using a new high-throughput approach that overcomes low bacterial biomass and interfere...

nature.com

The Molecular Foundry turns 20 today. 🔬✨ Two decades of open-access nanoscience at @berkeleylab.lbl.gov— thousands of users, discoveries, and stories. Explore 20 years of impact: foundry.lbl.gov/impact/

New research points to the oil-producing alga Auxenochlorella as a powerful platform for producing specialty oils, chemical feedstocks and industrial precursors—as well as to better enable the mining of critical minerals and materials. 🖥️🧬 @berkeleylab.lbl.gov @axelvisel.bsky.social @biosci.lbl.gov

Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering | Joint Genome Institute

Streamlined genome with precise gene targeting transforms oil-producing alga into a powerful platform for developing ​​bio-based industrial products.

jgi.doe.gov

🚨 Job Alert - Please share! 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! We’re recruiting: ✅ PhD students ✅ Postdocs 💻🧪 Experimental or computational backgrounds welcome 👇 Details below

📣Deadline 4/9: The JGI is currently accepting LOIs for our Community Science Program's Large Scale call — for mission-relevant genomic science projects that leverage systems-based approaches. Learn more: jointgeno.me/LargeScaleCSP @berkeleylab.lbl.gov @biosci.lbl.gov @axelvisel.bsky.social

CSP Large Scale Call | Joint Genome Institute

The Community Science Program Large Scale Call is focused on genomic science projects that address sustainable biofuel and bioproducts production.

jointgeno.me

Last reminder: Sign up for the webinar now!

Axel Visel@axelvisel.bsky.social · 6mo ago

Critical Minerals and Materials Genomics🧬 meets Nanoscience🔬 to enable recovery, reuse, and transformation of CMMs New joint user opportunity from @jgi.doe.gov and @molecularfoundry.lbl.gov at @berkeleylab.lbl.gov Join our informational webinar on Feb 27, 9am PT: jgi.doe.gov/work-with-us...

Our FY25 Progress Report is now live! We broke our own record by sequencing more than 1Pb of data in a year—on top of serving 2,627 users w/active proposals, plus 17K researchers making use of our data. 🖥️ 🧬 🌱 🍄 🦠 🧪 Full report: https://jgi.doe.gov/user-science/science-stories/2025-progress-report

2025 Progress Report | Joint Genome Institute

Learn more about the JGI's 2025 accomplishments, including research and data output.

jgi.doe.gov

📣 We're joining up with @jgi.doe.gov in a joint Critical Minerals & Materials Call 👀: https://bit.ly/3MvzWy6 This is an opportunity to use the capabilities and expertise of both facilities. The call opens March 1. You can register for our Feb. 27 webinar now: https://bit.ly/3Oox1I0

Critical Minerals and Materials Genomics🧬 meets Nanoscience🔬 to enable recovery, reuse, and transformation of CMMs New joint user opportunity from @jgi.doe.gov and @molecularfoundry.lbl.gov at @berkeleylab.lbl.gov Join our informational webinar on Feb 27, 9am PT: jgi.doe.gov/work-with-us...

“All chestnut trees here are doomed.” — NY Times, 1911 A century ago, pathogens wiped out over 4 billion American chestnuts. New genomic resources are helping reverse their functional extinction. 🌳🧬 Jared Westbrook, @jgi.doe.gov's @jotlovell.bsky.social et al.: www.science.org/doi/full/10....

Neil H. Shubin has been elected as the next NAS President! A leading evolutionary biologist and science communicator, Shubin will succeed Marcia McNutt on July 1. The Academy also named Cherry Murray as International Secretary and elected new councilors. Read more: www.nasonline.org/news/2026_pr...

Last reminder!

Axel Visel@axelvisel.bsky.social · 6mo ago

⏱️Deadline reminder: February 3rd, 2026 Register and submit your abstract for the upcoming @jgi.doe.gov -EMSL meeting in Seattle Do it now, or do it like Kermit. Up to you. jgi.doe.gov/work-with-us...

Myth of Fact? 🌿Plant pangenomes show massive presence-absence variation affecting protein-coding gene content 🧬 @jgi.doe.gov's @tomasbruna.bsky.social @jotlovell.bsky.social @avril-m-harder.bsky.social and Avinash Sreedasyam searched for answers academic.oup.com/nargab/artic...

⏱️Deadline reminder: February 3rd, 2026 Register and submit your abstract for the upcoming @jgi.doe.gov -EMSL meeting in Seattle Do it now, or do it like Kermit. Up to you. jgi.doe.gov/work-with-us...

What can we learn from comparing ~2,000 fungal genomes? Find out about: 🍄evolutionary transitions 🍄lifestyles 🍄genome dynamics 🍄sampling gaps 🍄efforts to uncover the remaining fungal dark matter New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev www.nature.com/articles/s41...

This is very sad news 'It is with great sadness that EMBL announces that Interim Director General Professor Peer Bork passed away from natural causes on 16 January 2026.' www.embl.org/news/embl-an...

In remembrance of Peer Bork  | EMBL

EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

embl.org

TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread

Seppe De Winter@seppedewinter.bsky.social · 7mo ago

We are thrilled to share our new pre-print: “System-wide extraction of cis-regulatory rules from sequence-to-function models in human neural development”. S2F-deeplearning models can accurately encode enhancers, yet decoding these models into human-interpretable rules remains a major challenge.

"Tidestromia oblongifolia took only two days to increase its photosynthetic capacity to produce energy and thrive in extreme heat, and by day 14 reached its ideal photosynthetic temperature of 45 °C (113 °F)" #PlantScience #PlantStress #ClimateChange Original paper: www.cell.com/current-biol...

The 'Hell-Plant' of Death Valley offers hope to a hotter world

We humans are a delicate bunch. We don’t have bark, boney exo-plates, or lush fur to protect us from hostile environments, so we have to steal what other creatures produce just to survive in regions a...

newatlas.com

Our work on #RegulatoryTrajectories is out today in Nat. Comms: www.nature.com/articles/s41... Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)

Our paper on the Expanded Registry of candidate cis-Regulatory Elements (cCREs) is out 🎉 www.nature.com/articles/s41... To celebrate, here’s a "meme-torial" walkthrough of the science. Let’s get started 🧵 1/11

a man wearing a plaid shirt and a purple hat is saying here we go .

ALT: a man wearing a plaid shirt and a purple hat is saying here we go .

media.tenor.com

Now out: The new ENCODE registry of candidate cis-regulatory elements (🐭/👶) Major consortium effort, led by @moorejille.bsky.social - stay tuned for her "meme-torial" www.nature.com/articles/s41... @berkeleylab.lbl.gov @biosci.lbl.gov

Jill Moore@moorejille.bsky.social · 7mo ago

Our paper on the newest version of the Registry of candidate cis-Regulatory Elements (cCREs) is out 🧬 Huge thanks to the many collaborators, experimentalists, analysts and software developers who made this work possible — truly a team effort! A "meme-torial" of the science is coming soon 👀

Congrats to the 14 researchers with proposals accepted for our 2026 Large Scale call! These projects accelerate bioenergy innovation through genomic discovery across diverse organisms and ecosystems. 🖥️🧬🦠🌱🧪🍄 More: jgi.doe.gov/user-science... @berkeleylab.lbl.gov @axelvisel.bsky.social

JGI Announces FY26 Large Scale Portfolio for Our Community Science Program | Joint Genome Institute

jgi.doe.gov