Cologne friends, looking forward to host the one and only Dan Corp here next week – feel free to drop by if you are free. 👇👇

New publication using Lead-DBS: In this article by Luo et al., the authors identified brain circuits associated with gait impairment after stroke and with gait changes following subthalamic DBS for Parkinson's disease, and found lesio... Check out the paper here 👇👇 https://doi.org/10.1002/ana.78320

Fantastic talk by @barbarahollunder.bsky.social on weaving together findings across studies in the field of connectomic DBS at the Würzburg expert summit!

Some great presentations at the DBS 3rd Expert Summit. And then there's @barbarahollunder.bsky.social absolutely knocking it out of the park! So cool to see her work shine doi.org/10.1038/s41593-024-01570-1

A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method. See below 👇 for our response. www.biorxiv.org/content/10.6...

Michael Fox@foxmdphd.bsky.social · 6mo ago

A recent paper in @natureportfolio.nature.com raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" www.biorxiv.org/content/10.6...

Shining a light onto the subcortex of the human brain 👇👇🔥🔥

Andreas Horn@andreashorn.org · 7mo ago

"You see what you look for, and you look for what you know." We are proud to release FOCUS: a 100 μm deformable human subcortical atlas precisely registered to MNI space. www.biorxiv.org/content/10.6...

New @netstim.org publication alert: @bahnebahners.bsky.social in BRAIN out now: academic.oup.com/brain/advanc... A 🧵:

The deep brain stimulation response network in Parkinson’s disease operates in the high beta band

Bahners et al. identify a brain network linked to optimal therapeutic outcomes in patients with Parkinson’s disease receiving deep brain stimulation. This

academic.oup.com

✨ Be there or be square! ✨ In our upcoming Stimulating Brains session (Feb 26, noon ET / 6 pm CET), let’s dive into the brain networks driving chronic pain and how adaptive DBS is changing treatment! 🎤 Feat. Valentina Lind & Prasad Shirvalkar 🔗 Get your Zoom link here: talks.stimulatingbrains.org

See you in Geneva! We have such an incredible line up of speakers this year! #optoDBS2026 – registration now open at www.optodbs.ch As last time, we are expanding scope way beyond just DBS and optogenetics – for instance including TMS and LIFU applications this year!

🎄🧠 Ho ho ho! Let’s close out the year with fresh insights into the brain networks behind creativity — and what happens when they go awry. Our December session (Thurs, Dec 18, noon ET / 6pm CET) will feat. @isaiahneuro.bsky.social & Ben Shofty. ✨ Get Zoom link here: mgb-org.zoom.us/webinar/regi...

In Buzzy Papers we set out to compile some of the most exciting neuroscience papers published in the past two years! A panel of 10 neuroscientists selected the papers from a preliminary list our editorial team assembled by considering publications in top neuroscience journals

The Transmitter @thetransmitter.bsky.social · 10mo ago

The field is buzzing about work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations and more. www.thetransmitter.org/community/th... #neuroskyence #StateOfNeuroscience

Thrilled to share my very first publication, in Translational Psychiatry! 🧠🧪 We used invasive brain mapping to identify personalized neuromodulation targets for treatment-refractory OCD. Read it here 👉 www.nature.com/articles/s41... #OCD #DBS #Neuroscience #Research

Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity - Translational Psychiatry

Translational Psychiatry - Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity

nature.com

Super excited for Ningfei Li to receive the highly prestigious NSFC Excellent Young Scientists Fund – as of yesterday, Ningfei is Full Professor at the Xian University and has joined a new AI institute! We are both excited to continue our collaboration on @lead-dbs.org and connectomic DBS!

Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b

A human brain network linked to restoration of consciousness after deep brain stimulation - Nature Communications

In people with severe brain injuries, stimulation restored consciousness by engaging a deep brain circuit for wakefulness—revealing a target that may also guide treatment in stroke and epilepsy.

nature.com

@foxmdphd.bsky.social's legendary anticorrelation paper has now been cited over 10.000 times and this was reason for a dedicated PNAS cake. Congratulations again, Mike, for this unbelievable pioneering effort that opened up the then novel field of resting-state fMRI! @braincircuits.bsky.social

Andreas Horn@andreashorn.org · last yr.

What a number! 🔜 🎉🥳🎊🍾 @foxmdphd.bsky.social!

What a number! 🔜 🎉🥳🎊🍾 @foxmdphd.bsky.social!

Hard to keep track about all the great things our labmembers have achieved recently:

Now available in typeset form - gift link to study: www.sciencedirect.com/science/arti...

Andreas Horn@andreashorn.org · last yr.

Interested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder? Take a look at our summary of this exciting field and how things could be brought together out now in BPS: www.biologicalpsychiatryjournal.com/article/S000... A brief 🧵

Very hard to say goodbye to these fantastic people. I will miss you guys! @braincircuits.bsky.social!

Probably the most insightful and most important paper on physiomarkers of subthalamic DBS in a long while. Bravo @julianneumann.bsky.social @tsbinns.com and team!! Out at @natcomms.nature.com: www.nature.com/articles/s41...

In this month’s “Liftoff,” Thomas Elston talks about the need for new PIs to develop their ability to cultivate others' thinking, and @taylersheahan.bsky.social explains how opening a lab is a lot like early parenthood. By @franciscorr25.bsky.social #neuroskyence bit.ly/4j7G1f3

Liftoff: New lab alerts

Learn about early-career scientists starting their own labs.

bit.ly

Was fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...

What brain damage tells us about creativity - ABC listen

Scientists have long been aware of a paradox of neurodegenerative disease – that as the brain deteriorates, in some patients creativity flourishes. Researchers have used imaging techniques to map cre...

abc.net.au

Looking for an awesome postdoc opportunity in neurophysiology and neuromodulation? Then check out this exciting opening! You’ll work on cutting-edge research, all while being mentored by @carinaoehrn.bsky.social – one of the most talented and fun people around. Can’t beat that!

Carina Oehrn@carinaoehrn.bsky.social · last yr.

We’re hiring! My lab @ucdaviscns.bsky.social is recruiting two postdocs in human intracranial neurophysiology & neuromodulation! We study cognition & emotion in movement disorders, record direct cerebellar & basal ganglia activity in real-world settings & develop adaptive DBS for non-motor symptoms.

I learned so much from a very sharp mind in this conversation. Equipped w an undergrad mathematics at Harvard, Medschool at Harvard, PhD at MIT, Terry has begun deeply thinking about dystonia and neuromodulation early on and has come up with a very unique sEEG based approach to treat tough cases.

Stimulating Brains@stimulatingbrains.org · last yr.

We had a wonderful conversation with Dr. Terry Sanger from CHOC who is a very inspirational figure and innovator in the field of DBS – with a special focus on treating pediatric forms dystonia / cerebral palsy. Tune in here 👇👇 stimulatingbrains.org/69-terrence-...

Check out our latest release of Stimulating Brains with a introduction recorded by a newcomer 😏! Dr. Sanger talked about how his background in neuroscience, engineering and clinical experiences shaped his path to become one of the top pediatric neurologists. Stay tuned 🥳🥳🥳

Andreas Horn@andreashorn.org · last yr.

I learned so much from a very sharp mind in this conversation. Equipped w an undergrad mathematics at Harvard, Medschool at Harvard, PhD at MIT, Terry has begun deeply thinking about dystonia and neuromodulation early on and has come up with a very unique sEEG based approach to treat tough cases.

Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:

A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications

Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...

nature.com

We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1... 1/n

Had a really insightful conversation with @toddherrington.bsky.social, the director of the DBS program at @massgeneralbrigham.bsky.social MGH about adaptive DBS, stem cell research and novel forms of neuromodulation! Tune in here 👇🎧👇🎧

Stimulating Brains@stimulatingbrains.org · last yr.

Adaptive DBS was recently approved by the FDA – in this episode, we talk with @toddherrington.bsky.social about the underlying ADAPT-PD trial, the mechanism of action of DBS, and the potential role of stem cell therapy in movement disorders. Tune in here 👇🎧👇🎧 stimulatingbrains.org/68-todd-herr...

Happy to share our most recent paper about the neural underpinnings of essential tremor. We mapped tremor-related changes of thalamocortical coupling and provide evidence for thalamo-cerebellar synchronization. Congrats to 1st author Alex Steina and thank u Düsseldorf team! doi.org/10.1002/mds....

Oscillatory Coupling Between Thalamus, Cerebellum, and Motor Cortex in Essential Tremor

Background Essential tremor is hypothesized to emerge from synchronized oscillatory activity within the cerebello-thalamo-cortical circuit. However, this hypothesis has not yet been tested using loc.....

doi.org

If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...

Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits

The rapid development and clinical use of brain stimulation has renewed debates about whether to define and accredit a pathway for clinical subspecial…

sciencedirect.com