Excited to share a paper recently accepted at Nature Mental Health! 😄 For decades, we've assumed that covariance among psychopathology informs comorbidity. What if we’ve been wrong?

PsyArXivBot@psyarxivbot.bsky.social · 4w ago

Covariation among higher-order psychopathology dimensions is driven by nomorbidity, not comorbidity: https://osf.io/3t2cm

🚨 preprint alert !!! Emotional and physical abuse have dissociable impacts on punishment learning and task engagement during adolescence osf.io/preprints/ps...

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

Another fresh preprint from the lab! Menarche marks an inflection point for female brain and mental health trajectories. This milestone may identify a critical window for screening. This is an effect you don't need stats to see (though we did those too). Led by @carinaheller.bsky.social 🧵👇

Carina Heller, Ph.D.@carinaheller.bsky.social · 4mo ago

🚨Preprint Alert 🧠 Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online! 👉 Preprint available here: www.biorxiv.org/content/10.6...

🚨Preprint Alert 🧠 Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online! 👉 Preprint available here: www.biorxiv.org/content/10.6...

Very excited to announce our new preprint, led by @hollysully.bsky.social, that presents, benchmarks, and validates a method to estimate brain iron content from routine fMRI scans! It comes complete with a BIDS app! Check out the preprint and thread below! doi.org/10.64898/202...

Holly Sullivan-Toole@hollysully.bsky.social · 4mo ago

🚨Preprint Alert🚨 Our new preprint 'A Scalable fMRI Estimate of Basal Ganglia Brain Tissue Iron for Use in Developmental and Translational Neuroscience' is live!! lnkd.in/gpG9naba

Updated preprint: doi.org/10.1101/2025... We have improved DELSSOME and showed that we can accelerate the estimation of two new biophysical models. By collating 12,005 individuals, we derive normative trajectories of cortical E/I ratio across the lifespan ...

Thomas Yeo@bttyeo.bsky.social · last yr.

While the world burns, we cook up a new preprint! doi.org/10.1101/2025... Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N

We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, “Two Axes of White Matter Development”, is now out in @natcomms.nature.com! 🛣️🧠✨ 🔗 bit.ly/wm2axes

“These findings provide clear evidence that data collected on MTurk simply cannot be trusted.”

New paper & a thread on the results 👇 ‘Reward-specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression’ acamh-onlinelibrary-wiley-com.ezp3.lib.umn.edu/doi/full/10....

Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels? Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202... Thread below 🧵

Anatomical White Matter Tracts Span the Cortical Hierarchy to Support Cognitive Diversity

Long-range white matter (WM) tracts support cognition by enabling communication between distant cortical regions, which are organized along a hierarchy defined by the sensorimotor-to-association (S-A)...

doi.org

Very happy to share our paper on the "summer slide" in kid's cognitive test scores is out now in @pnas.org! We find a replicable dip in performance across multiple domains of cognition in >23,000 kids across 4 datasets! Check out the 🧵 from @ariellekeller.bsky.social below! 👇

Arielle Keller@ariellekeller.bsky.social · 8mo ago

Our paper on the ☀️ "summer slide" 🛝 is out now @pnas.org! www.pnas.org/doi/10.1073/... Summer slide is a replicable phenomenon across diverse datasets that's more than "forgetting" school material in vacation months, but effects of socioeconomic inequality are ➡️ 7x bigger! ⬅️ #PsychSciSky #DevPsy 🧵👇

Excited to share our new review “Mapping interactions between adversity and neuroplasticity across development” in @cp-trendscognsci.bsky.social. We discuss how experience - particularly adversity - interacts with neuroplasticity during human development authors.elsevier.com/c/1mB5U4sIRv...

Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology. pbs.jhu.edu/about/jobs/

Jobs | Psychological & Brain Sciences

Tenured/Tenure-track position in Cognitive Psychology Open Date Dec 01, 2025 Salary Range or Pay Grade The expected academic base salary range for this position is $110,000- $144,500 (Assistant Profes...

pbs.jhu.edu

Is the “standard workflow” holding back fMRI analysis? Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.

I can't recommend this fantastic new review from @valeriejsydnor.bsky.social enough! It does an amazing job of synthesizing the current state of the literature and then looking forward to provide a fresh perspective on how to move this work forward in humans. Check it out!

Valerie Jill Sydnor@valeriejsydnor.bsky.social · 9mo ago

Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications

The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...

biorxiv.org

I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN. It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package. Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats

ggplot2 4.0.0

A new major version of ggplot2 has been released on CRAN. Find out what is new here.

tidyverse.org

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

This paper truly exemplifies what is possible in the modern era of neuroimaging data. A beautiful and extremely impressive piece of work from @valeriejsydnor.bsky.social that was a treat to contribute to. Check it out!

Valerie Jill Sydnor@valeriejsydnor.bsky.social · last yr.

How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...

OK, It is not just the HBCD release... docs.hbcdstudy.org It’s the ABCD Release time too! docs.abcdstudy.org nbdc-datahub.org That means the ABCC 3.0.0 is live!!! The largest release yet from the ABCD-BIDS Community Collection. This is going to be fun!! 👇 Let’s dig in.

Damien Fair@drdamienfair.bsky.social · last yr.

Alert! ... for the child development world! @fluxsociety.bsky.social @fitngin.bsky.social ‪ The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive. Check here: docs.hbcdstudy.org and here: nbdc-datahub.org Here’s why it matters 🧠🍼

Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠 #neuroskyence #neuroimaging #psychscisky

Arielle Keller@ariellekeller.bsky.social · 2y ago

✨New Preprint!✨ Sex differences in psychiatric disorders often show up in adolescence as disparities in prevalence, symptoms, and treatment outcomes. We aimed to understand sex diffs in brain organization that might lead to these disparities! t.ly/x6oxC 🧵⬇️ #neuroskyence #psychscisky #Neuroimaging

While the world burns, we cook up a new preprint! doi.org/10.1101/2025... Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N

Awesome opening salvo from the lab of @lindenmp.bsky.social!! Super cool work that will stem many future directions!

Linden Parkes@lindenmp.bsky.social · last yr.

Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘 www.biorxiv.org/content/10.1...

Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇 #interoception 🧠🫀 #neuroskyence elifesciences.org/reviewed-pre...

Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back. This was the largest political gathering in Denver since Obama in 2008. Also bigger than the 2024 DNC. And the largest ever rally in Bernie’s career (and obviously, mine too).

We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1... 1/n

Great analysis of the indirect cost rate announcement by @stuartbuck.bsky.social

Indirect Costs at NIH . . .

I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:

open.substack.com

For those who don't know, here are very real research costs that directs cannot cover - all fall within indirects: the buildings we work in (upkeep, maintenance, cleaning, etc), utilities, IT infrastructure, human resources, administrative staff, security, and lots more

BWJones@bwjones.bsky.social · last yr.

The new NIH policy for indirect costs going forward is capped at 15%. This is forever going to alter the science ecosystem, upending and destroying a number of programs at universities across the country. grants.nih.gov/grants/guide...

Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠

Imaging Neuroscience@imagingneurosci.bsky.social · 2y ago

New paper in Imaging Neuroscience by Julia Moser, Damien A. Fair, et al: Multi-echo acquisition and thermal denoising advances precision functional imaging direct.mit.edu/imag/article...