Jon Boyle
@boylelab.bsky.social
Professor of Biology at University of Pittsburgh. Toxoplasma evolution placenta interactions virulence development. tragically a pirates fan can’t help it
Longing for pre AI and pre Biorender schematics in scientific papers? Me too.
Our work just came out today in print form in Nat Micro. Really a tour de force from Hisham Alrubaye on sexual development in Toxoplasma gondii. Well done! rdcu.be/feOj6
A single-cell atlas of Toxoplasma sexual development in the feline intestinal tract
Nature Microbiology - Single-cell RNA sequencing is used to study the sexual development of Toxoplasma gondii in cats, generating a transcriptional atlas and showing that the female-specific gene...
rdcu.be
Fighting through snow so I can do my science. Animal care staff, building staff, clinical staff, nurses, doctors, veterinarians all work through these weather conditions to make the NIH run.
Today I submitted a grant and I’m also getting a tooth pulled today which do yall think will be worse
This is the fucking best. Rip city forever indeed
It's a whole block party vibe over here.
“I’m a transgender service member and today was my last day in uniform. After 11 years, eight months and 1 day I’m taking the uniform off for good. I will always be yours bc this rank, these skills, this name will always be me.” ~Technical Sargent Altesse Aurum #TransInMilitary 🫡 🏳️⚧️ @altessaurum
Today, we received notice that our team’s last remaining NSF grant was terminated. For the first time since 2009, when I received an NSF Fellowship for Graduate Research, I have no active NSF grants.
Heartbreaking effects of NSF, Americorps cuts to Pittsburgh’s after school programs that support and enrich our city’s kids. The need and benefits of these programs is obvious. Isn’t this what we pay taxes for? Doubt philanthropy can take over. www.publicsource.org/federal-fund...
Pittsburgh after-school programs left scrambling as federal funding cuts hit the region
Pittsburgh-area programs reel with recent federal grant terminations from the National Science Foundation.
publicsource.org
This, more than anything else they are doing with funding levels etc, will ruin US Science and innovation.
tl;dr — this EO co-opts the language of open science to implement a system of political control wherein presidential appointees are given broad latitude to designate any number of reasonable scientific activities and inferences as scientific misconduct, and to penalize those involved accordingly.
Just called Gillibrand and Schumer to demand they not only vote against the murderous Republican budget bill, but that they deny unanimous consent at every opportunity and do everything else they can to gum up the works. This is intolerable. Find your senators here and make your own calls: reps.fyi
cis people: please call your senators today. Please please please. this is so critical. we’re begging you
⚖️Heartbroken but proud to stand with fellow researchers in court today⚖️ NIH’s sudden grant cuts: 🚫 Silence lifesaving health equity work ⏳ Undermine years of progress ⚠️ Put vital discoveries at risk We won’t stop fighting for science & justice 🧪 👇More details from our @aclu.org representation👇
‘Devastated’ and ‘Hopeless.’ Researchers Speak Out on Funding Cuts | ACLU
aclu.org
Amazing super cool and IMPOSSIBLE without a) NIH funding and b) ANIMAL RESEARCH
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —from decades of NIH funded research www.nejm.org/doi/full/10.... @nejm.org www.nejm.org/doi/full/10.... www.nytimes.com/2025/05/15/h...
Ok so I agree re: HIM but sadly what he’s saying here is “do your own research and be skeptical of experts”.
Kennedy adds: “I don’t think people should be taking advice, medical advice, from me.”
The canceled grants aren't a perfect 1:1 with DEI-related projects, but what a reminder of who is and isn't doing the work to make science more equitable.
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants. Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Another scoop from Jeff Mervis (@policyhound.bsky.social): NSF's ~1400 grant terminations have disproportionately affected PIs from groups underrepresented in science: women, racial & ethnic minorities, & those with disabilities. 1/3 www.science.org/content/arti...
The intense racial and gender segregation of science funding will be even more pronounced going forward. This was always the intent.
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants. Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
they put french fries in sandwiches rich that is what the heck is going on in pittsburgh i am all for it tbh
EvolvingSTEM in action at Pittsburgh Perry HS @evolvingstem.bsky.social www.wtae.com/article/pitt...
Federal freezes threaten Pitt's STEM outreach in high schools
Scientists at the University of Pittsburgh have been teaching inside local high schools for ten years through the Evolving-STEM program, which now faces potential federal funding cuts.
wtae.com
I had an NSF grant on AI education canceled yesterday. I wasn’t given any kind of reason but I have a theory and it’s just as stupid as you might think. (I will probably have more to say on this once I have more details but for right now just: 😡 )
Just one example: In the past 2 weeks, NIH has terminated dozens of programs to support students pursuing scientific careers. These MARC or U-RISE (T34) grants provide rising undergraduates with opportunities and stipends to participate in science. Where are these programs? Not in the Ivy league:
Ai to predict how a specific monoclonal antibody will distribute throughout the body 👍
This is chilling www.fda.gov/news-events/...
Here’s how they’ll do it: 1. Say a lot of people are faking it 2. Vaccines 3. Food
The agenda is becoming clearer rollcall.com/2025/04/10/k...
Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.
Given today's onslaught on HHS, I'm resharing my OpEd in @elife.bsky.social. You are not alone, and you do have an important voice! Many colleagues remain unaware that the foundation of US biomedical research is crumbling under attack. Tell them! Full text 🔗 elifesciences.org/articles/106...