Tessera
Folgen

Carsten Schulte

@carstenschulte4.bsky.social

Interdisciplinary cell biologist fascinated by (extra)cellular mechanobiology in (patho)physiology. Lecturer, Department of Biomedical Engineering @University of Strathclyde & CeMi. Tweets about science & other stuff in which I engage. Views are my own.

255 Posts3097 Follower3835 Folgt
Carsten Schulte@carstenschulte4.bsky.social · 6mo ago

New PhD opportunity in my lab📣! The PhD studentship* will be embedded in a broader project looking at glioblastoma from a mechanobiological angle, funded by a recently granted Springboard award from the @acmedsci.bsky.social 🙏. *only home student fees covered 👉 www.findaphd.com/phds/project...

Leveraging mechanobiology for the dissection of stem-like properties and therapeutic resistance potential in glioblastoma cells at University of Strathclyde on FindAPhD.com

PhD Project - Leveraging mechanobiology for the dissection of stem-like properties and therapeutic resistance potential in glioblastoma cells at University of Strathclyde, listed on FindAPhD.com

findaphd.com

Barbieri Mariano PhD@barbierimarianophd.bsky.social · 8mo ago

Fantastic work connecting mechanotransduction stimuli, changes in 3D nuclear structure and cell identity! Must read

Carmelo Ferrai@carmeloferrai.bsky.social · 8mo ago

Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below) "The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A. www.biorxiv.org/content/10.6...

Carsten Schulte@carstenschulte4.bsky.social · 8mo ago

It finally happened. I'm beyond happy to see this work with @carmeloferrai.bsky.social is out now. This collaboration to study the link between mechanotransduction and epigenetic regulation started quite a while ago. It is kind of a miracle that we eventually got to this point against all odds.

Carmelo Ferrai@carmeloferrai.bsky.social · 8mo ago

Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below) "The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A. www.biorxiv.org/content/10.6...

Carsten Schulte@carstenschulte4.bsky.social · 11mo ago

I would call it the "Matthew effect" grant! Why is it that we always demand to "listen to the science", but when it comes to science related to the flaws and issues of our current research funding structure (and scientific publishing system for that matter), we are completely ignorant...?

Katherine Stiles@katherinestiles.org · 11mo ago

· #AcademicSky · The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.

Carsten Schulte@carstenschulte4.bsky.social · 11mo ago

Completely wrong direction imo. It would be better and more efficient to increase funding rates of existing schemes funding more of the already fundable, great ideas for projects that are out there instead of yet another call with, most probably, less than 10% success rate.

Katherine Stiles@katherinestiles.org · 11mo ago

· #AcademicSky · The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.

Guillaume Jacquemet@guijacquemet.bsky.social · 11mo ago

Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.

Katherine Stiles@katherinestiles.org · 11mo ago

· #AcademicSky · The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.

Carsten Schulte@carstenschulte4.bsky.social · last yr.

Congratulations Carmelo and team, brilliant work showing that mechanostimuli (through sound waves) can provoke nuclear chromatin responses in mesenchymal stem cells which directs the cells towards osteogenic lineage🤩!

Carmelo Ferrai@carmeloferrai.bsky.social · last yr.

Paper accepted!!!! Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊

Carmelo Ferrai@carmeloferrai.bsky.social · last yr.

EpiSci - 🧬 - 🧪 - 👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽 We just submitted an updated version of the previous preprint. Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells www.biorxiv.org/content/10.1...

Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells

Cells effectively balance and integrate numerous pathways to adapt to external signals in an attempt to regain homeostasis, although the complex nuclear mechanotransduction mechanism through which thi...

biorxiv.org

Carsten Schulte@carstenschulte4.bsky.social · last yr.

A little more than a year that @carmeloferrai.bsky.social and I published our review "Mechanotransduction in stem cells"🤯! I'm happy that it was received well 😃! Stay tuned, more to come in this direction in a not too far future😎.

Carmelo Ferrai@carmeloferrai.bsky.social · 2y ago

EpiSci - Hi there! Our review “Mechanotransduction in stem cells” is finally published. With @carstenschulte4.bsky.social we provided a comprehensive picture, that aims to cover the whole mechanotransductive pathway from the cell microenvironment to the nucleus. 1/3 pubmed.ncbi.nlm.nih.gov/38729084/

Carsten Schulte@carstenschulte4.bsky.social · last yr.

A paper that I published as a co-first author in 2014 (with G.M. Ferraris and V. Buttiglione, supervised by N. Sidenius, not on bluesky) reached 100 citations. Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now: 👉 www.embopress.org/doi/full/10....

The interaction between uPAR and vitronectin triggers ligand‐independent adhesion signalling by integrins | The EMBO Journal

image image Cell adhesion mediated by uPAR and other adhesion receptors triggers non‐canonical integrin activation independent of integrin–ligand interactions. The cross‐talk between adhesion recepto...

embopress.org

Amrei Bahr@amreibahr.bsky.social · last yr.

So ist es, liebes BMFTR: Die Chancen sind für jede Generation ✨vergleichbar schlecht✨! 12 Jahre prekäre Beschäftigung & anschließend fliegen die nicht mehr ganz so jungen Wissenschaftler_innen ins Weltall 🚀 … ah Moment … doch nicht … sie fliegen: RAUS! Das sind Chancen! #RundumSorglos #IchBinHanna

Screenshot der Website des BMFTR: „Chancen • Die speziellen Befristungsregelungen des WissZeitVG eröffnen jeder Generation junger Wissenschaftlerinnen und Wissenschaftler vergleichbare Chancen auf wissenschaftliche Qualifizierung und langfristige Karriere-perspektiven in der Wissenschaft.“
Marc Somssich@somssich.bsky.social · 3y ago

📜 A comprehensive strategy to strengthen bioimaging in Africa through the Africa Microscopy Initiative 🧑‍🔬 Michael Anton Reiche, Teng-Leong Chew, et al. 📔 Nature Cell Biology 🔗 www.nature.com/articles/s41... #️⃣ (Feeds) #Microscopy #CellBiology #AfricaMicroscopyInitiative

A comprehensive strategy to strengthen bioimaging in Africa through the Africa Microscopy Initiative...

The Africa Microscopy Initiative (AMI) aims to promote the use of microscopy in biomedical research through facilitated access to instruments and expertise, and via training and networking opportuniti...

nature.com