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Carmelo Ferrai

@carmeloferrai.bsky.social

RNAPII &Transcription Regulation -Chromatin Conformation & Nuclear Architecture - ESCs & Neuronal Differentiation - Nuclear Mechanotransduction - Cell Plasticity UMG, Göttingen, Germany

1297 Posts3075 Follower941 Folgt
Akis (Argyris) Papantonis @akispapantonis.bsky.social · 3mo ago

PS: this is also an opportunity to showcase our powerful senescence model using a small molecule inhibitor. See thread on this here: bsky.app/profile/akis...

Akis (Argyris) Papantonis @akispapantonis.bsky.social · 3y ago

2024 start off on the right foot: our preprint on the repurposing of a small molecule inhibitor to induce rapid, synchronous and SASPless senescence to human cells is now out in Aging Cell! A multi-lab effort led by former PhD student S. Palikyras onlinelibrary.wiley.com/doi/10.1111/...

Giacomo Donati@giacomodonatijd.bsky.social · 2mo ago

The final version is now online! #RNALocalization #Chromatin #FunctionalGenomics #CellMigration #CancerBiology www.nature.com/articles/s41...

Multilayered control of mRNA delivery to cell protrusions drives localized mini-cytoplasm establishment for stress-induced cell activation - Nature Communications

Here the authors show that, under stress, epithelial cells reveal an unexpected role for a chromatin factor in directing mRNA to cell protrusions, enabling local organelle assembly and cell movement, ...

nature.com

Giacomo Donati@giacomodonatijd.bsky.social · 3mo ago

How do cells build functional protrusions during stress? In our @natcomms.nature.com paper, we uncover a CBX3-dependent chromatin-to-protrusion mRNA transport pathway that organizes a local "mini-cytoplasm" to drive cell activation, migration and invasion. Here's the story 🧵👇 doi.org/10.1038/s414...

Carmelo Ferrai@carmeloferrai.bsky.social · last mo.

Prof. Jacopo Meldolesi passed away. He was a great teacher and a lovely person with an extraordinary passion for neuroscience to which he tirelessy dedicated his life. Farewell Jacopo it was a privilege knowing you and sharing with you a few steps on the journey of scientific discovery. RIP Jacopo

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Simon Stitzinger@simonstitzinger.bsky.social · last yr.

Are you in Freiburg and interested in biophysics? Remember to sign up for the Biophysical Coffee ☕ Meeting Freiburg, only a few days are left! Talks and Posters will be selected from registered participants. Participation is free, but registration is required. www.ie-freiburg.mpg.de/events/41674...

1st Biophysical Coffee Meeting Freiburg

To enhance the exchange and interaction among people working on biophysics in Freiburg, we are organizing the Biophysical Coffee Meeting Freiburg, which will take place on July 4, 2025 at the Max Plan...

ie-freiburg.mpg.de

Simon Stitzinger@simonstitzinger.bsky.social · last yr.

Friends of biophysics in Freiburg, listen up! Join us for the Biophysical Coffee Meeting Freiburg on July 4, 2025, at the MPI-IE. There will be talks, chalk talks, posters, and plenty of time for discussion and to exchange ideas. Please sign up until June 13 (register.ie-freiburg.mpg.de/event/10/).

Poster advertising the Biophysical Coffee Meeting Freiburg on July 4, 2025, at the MPI-IE. The event starts at 14:00h. Registration is possible at https://register.ie-freiburg.mpg.de/event/10/ until 13 June, 2025.
Jean-Paul Armache@valendraica.bsky.social · 3mo ago

If you or someone you know is interested in joining a fun and productive lab (JP Armache laboratory at Penn State University) to work on exciting projects, please follow or share the link below. psu.wd1.myworkdayjobs.com/PSU_Academic...

Postdoctoral Position

APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

psu.wd1.myworkdayjobs.com

Mathis Riehle@mornorse.bsky.social · 3mo ago

Last week I attended the 6th 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝗼𝗻 𝗠𝗲𝗰𝗵𝗮𝗻𝗼𝗯𝗶𝗼𝗹𝗼𝗴𝘆 #ISMB2026 that was organised as part of SynSci — Synergy for Science 2026 and did some #Sketchnotes along the way; I plan to add the missing ones with time… bio-mat-sketches-mor.blogspot.com/2026/07/2026...

2026 International Society for Mechanobiology meeting in Glasgow at SynSci

A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.

bio-mat-sketches-mor.blogspot.com

Mark Peifer (He, him)@peiferlabunc.bsky.social · 3mo ago

Multi-ciliated cells drive many key events, including, for example, expelling pathogens and debris from our lung airways. @raghavan-thiaga.bsky.social Provides a great introduction to the cell biology behind this, and the many unanswered questions. Plus lovely images!! Check it out. 🧪

epithelial mechanics fan club@epimechfc.bsky.social · 3mo ago

From single-celled organisms to ciliated epithelia in metazoans, precise positioning of basal bodies (BBs), which anchor motile cilia, is essential for generating fluid flows. Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.

James Briscoe@jamesbriscoe.bsky.social · 3mo ago

Paying peer reviewers Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review Spoiler: it works - fast, high quality reviews www.nature.com/articles/d41...

Why paying peer reviewers works, according to a journal’s editor-in-chief

A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.

nature.com

Akis (Argyris) Papantonis @akispapantonis.bsky.social · 3mo ago

I have spent a long time resisting the use of AI in my everyday task, let alone in the process of scientific production (text, figures, ideas) which is anyway the bit of this weird profession that I enjoy the most. In the ensuing mini-rant, echoing Aydan’s thoughts, I want to highlight few things…

Aydan Bulut-Karslioglu@bulutkarslioglu.bsky.social · 4mo ago

I have been thinking since yesterday about why I find the 1% thing so, so disturbing. It's a visceral reaction of 'just no', which goes beyond the general yuck towards the enshittification of/via AI. I have finally put my finger on it: it is the feeling you get when

Teif lab@teiflab.bsky.social · 3mo ago

1/9 A few thoughts and personal opinions on the use of AI in research evaluation. I suspect many of these changes may be inevitable, so the real question may not be whether this will happen, but how we shape it responsibly 🧵

Carmelo Ferrai@carmeloferrai.bsky.social · 3mo ago

How does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. hubs.la/Q04mQjrC0

Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identity

Plasma membrane identity depends on tight control of anionic lipid composition, but how cells sense and correct imbalances remains poorly understood. Huang

hubs.la

Journal of Cell Biology@jcb.org · 4mo ago

How does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. rupress.org/jcb/article/... @jeremybaskin.bsky.social