Is diet-induced obesity driven by overeating? Or is there another and perhaps more important driver?💡1/5 @easoobesity.bsky.social @cbmr.science

Nine members of the Hansen group at the @cbmr.science Novo Nordisk Foundation Center for Basic Metabolic Research will be participating in the Study Group on Genetics of Diabetes (SGDD) conference this week! If you are attending as well, we would love to meet you at our talks and posters! 🧬

Online Now: A fuel partitioning perspective on appetite suppression by GLP-1 receptor agonists #trends #endocrinology #metabolism

A fuel partitioning perspective on appetite suppression by GLP-1 receptor agonists

Appetite suppression by glucagon-like peptide-1 receptor agonists (GLP-1RAs) is thought to result from direct actions on neural circuits controlling food intake. In this article, we (1) propose that a shift in fuel partitioning toward fat oxidation caused by GLP-1RAs contributes to appetite suppression and (2) explore potential lines of research to test this hypothesis.

dlvr.it

I am proud to have done this work alongside @johansenvbi.bsky.social under the supervision of Pablo Ranea-Robles and @clemmensenc.bsky.social at @cbmr.science, University of Copenhagen. Curious to learn more? Read it here: doi.org/10.1113/JP28...

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. ...

doi.org

We are delighted to learn that Vice Executive Director Professor @keisakamoto.bsky.social has been elected a Fellow of the @royalsoced.bsky.social! He says: "I am deeply honoured to be elected as a Fellow of the Royal Society of Edinburgh ... It inspires me to keep pursuing meaningful science."

#Throwback 🧪 COMMENT | Shaping the future of cardiometabolic innovation: advances and opportunities @clemmensenc.bsky.social et al

Shaping the future of cardiometabolic innovation: advances and opportunities - Nature Metabolism

Obesity is a global public health concern closely linked to cardiometabolic complications. This Comment provides our views on recent breakthroughs, emerging innovations and future needs of therapeutic interventions to counteract obesity and its associated health risks.

dlvr.it

Exercise timing and circadian regulation of metabolism in type 2 diabetes. Our latest review: Exercise modulates our biological rhythms, with timing emerging as an important factor for metabolic outcomes in type 2 diabetes. www.sciencedirect.com/science/arti...

Exercise timing and circadian regulation of metabolism in type 2 diabetes

The circadian system regulates daily rhythms in metabolism and hormone secretion; however, in type 2 diabetes, disrupted clock gene oscillations in sk…

sciencedirect.com

We recently welcomed two new members to our group @cbmr.science Postdoc Salim Hanna will be working on identifying translation-oriented approaches targeting #AMPK to improve muscle metabolic function. Research assistant, Frederik Gouliaev will be investigating AMPK and its phosphatases in the group.

We are just over half way through Metabolism Day 2026, with Dr Manon Mathias now on stage. Following her talk, the day ends with keynotes from Dr. Antje Körner and Sir Stephen O’Rahilly. Tune in on the livestream: www.youtube.com/live/sin5URc...

Metabolism Day 2026

YouTube video by CBMR at the University of Copenhagen

youtube.com

Metabolism Day strikes again 🔥 Amazing line up of speakers - and fascinating data by Matthias Tschöp to kick off the day! @cbmr.science

Metabolism Day 2026 is on! Join for free using the below link!

NNF Center for Basic Metabolic Research@cbmr.science · 5mo ago

Tune in to Metabolism Day on our YouTube livestream! First up is President Matthias H. Tschöp, Professor at Ludwig-Maximilians-Universität München on 'Dual and Triple Co-agonists: From Discovery to Best-In-Class'. www.youtube.com/live/sin5URc...

@juleenrzierath.bsky.social kicking off Metabolism Day 2026 #MD26 @cbmr.science Join in online 👇 www.youtube.com/live/sin5URc...

Tune in to Metabolism Day on our YouTube livestream! First up is President Matthias H. Tschöp, Professor at Ludwig-Maximilians-Universität München on 'Dual and Triple Co-agonists: From Discovery to Best-In-Class'. www.youtube.com/live/sin5URc...

Metabolism Day 2026

YouTube video by CBMR at the University of Copenhagen

youtube.com

Check out this meeting on whole-room indirect calorimetry in Denmark! Submit your abstract and join international peers to share ideas and spark new collaborations 👇 Free registration: ninaziegenbein.github.io/wricaarhus20... @stenoaarhus.bsky.social @cbmr.science @zgerharthines.bsky.social

@camillascheele.bsky.social promoted to Professor of Translational Cell Metabolism 🚀 💬"The signaling role of adipose tissue in metabolism is central to understanding cardiometabolic health.” cbmr.ku.dk/news/2026/th...

The Guasch Group is seeking adults aged 45–70 with an increased risk of cardiovascular disease to participate in a study on sustainable diets and health. Read more and sign up at planetdiet.dk If you have any questions, contact the team at planetdiet@sund.ku.dk or +45 93 51 84 39

A big congratulations and thank you for all the marvelous achievements & hardwork to all members of the group. Looking forward for a productive and eventful 2026! Merry Christmas and Happy New Year to everyone from the Sakamoto group @cbmr.science

New findings from @CBMR.science show that insulin-resistance-linked hyperinsulinemia is associated with colorectal cancer risk, but not other diabetogenic processes. Largest study yet on this link – led by postdoc Xuan Zhou and @jmerino.bsky.social link.springer.com/article/10.1...

Diabetogenic processes for insulin resistance-linked hyperinsulinaemia are associated with colorectal cancer - Diabetologia

Aims/hypothesis Type 2 diabetes has been associated with increased risk of colorectal cancer (CRC), but the specific diabetogenic pathways contributing to this risk remain unclear. Methods We analysed...

link.springer.com

Register now for Metabolism Day 2026! 🚀 The 7th annual conference about cardiometabolic diseases and energy control takes place on March 10, 2026 at @ucph.bsky.social, Denmark. Attend in-person or watch the live stream. Read more and register on our website! eventsignup.ku.dk/metabolismda...

🔔 Excited to teach the PhD course “Bioinformatics Analysis of Gene Expression Data from Bulk RNA-seq” at University of Copenhagen! 📅 26 Jan – 12 Feb 2026 👍 Bring your own data (or use a public one) and learn the full RNA-seq pipeline:

"#Throwback 🧪 COMMENT | Shaping the future of cardiometabolic innovation: advances and opportunities @clemmensenc.bsky.social et al https://bit.ly/4iIBBvY

Shaping the future of cardiometabolic innovation: advances and opportunities - Nature Metabolism

Obesity is a global public health concern closely linked to cardiometabolic complications. This Comment provides our views on recent breakthroughs, emerging innovations and future needs of therapeutic interventions to counteract obesity and its associated health risks.

bit.ly

"I think we made a lot of our discoveries because of our tenacity and detective work. We were staying on it and not giving up." Learn more about CBMR Group Leader Professor Jens Juul Holst and his important role in discovering GLP-1: cbmr.ku.dk/news/2025/we...

"We were walking in the streets, chanting 'research for the people, not for profit'"

From emergency surgeon to discoverer of GLP-1 and its effects on insulin production and satiety, CBMR Group Leader Professor Jens Juul Holst has spent fifty years pursuing one question: how does metab...

cbmr.ku.dk

#Inuit genetic adaptations, evolved over 1000s of years as they adapted to a cold climate and consumed a diet largely consisting of marine mammals, influence circulating protein levels in the blood and may modify their risk of diabetes and cardiovascular disease today. cbmr.ku.dk/news/2025/an...

Ancient arctic adaptations may influence modern disease risk

Inuit in Greenland possess a unique genome, which has evolved over thousands of years as they adapted to a cold climate and consumed a diet largely consisting of marine mammals. Now, a team of interna...

cbmr.ku.dk

🌍 Excited to be part of this global effort! 🦠 Microbial and metabolic diversity was mapped across 51 vivaria & 12 wild colonies, revealing striking functional convergence despite taxonomic divergence. 🔗 www.cell.com/cell-host-mi...

"For decades, we’ve been told that weight loss is a matter of willpower: eat less, move more. But modern science has proven this isn’t actually the case." @clemmensenc.bsky.social and @johansenvbi.bsky.social in @theconversation.com 👇 theconversation.com/the-science-... #obesity #metabolism

The science of weight loss – and why your brain is wired to keep you fat

The evolutionary science of weight regain unpacked.

theconversation.com

A framework from @easoobesity.bsky.social to guide pharmacological treatment of 'fat mass diseases' versus 'sick fat diseases' 👇 www.nature.com/articles/s41...

Framework for the pharmacological treatment of obesity and its complications from the European Association for the Study of Obesity (EASO) - Nature Medicine

Obesity and associated complications can be managed by obesity medications, prompting the revision of criteria for the diagnosis and staging of this disease.

nature.com

Stoked to receive this award that will help to dissect the relative contribution of aberrant glycogen levels and impaired glycogenesis in influencing skeletal muscle glucose metabolism.

European Association for the Study of Diabetes@easdnews.bsky.social · 10mo ago

🎉👏 We’re thrilled to congratulate the 2025 #EFSD / Lilly Diabetes International Young Investigators Award recipients. Award recognises early career scientists/clinicians driving innovation in diabetes research. Learn more about their projects 👉 www.europeandiabetesfoundation.org/recipients/e...

🚨 Dealing with sparse, noisy single-cell DNA methylation data (scBS-seq)? Check out #scDMV. It uses a zero-one inflated beta mixture model to tackle the excess of 0s/1s and low coverage, boosting accuracy in identifying differentially methylated regions (DMRs).

scDMV: a zero–one inflated beta mixture model for DNA methylation variability with scBS-seq data

AbstractMotivation. The utilization of single-cell bisulfite sequencing (scBS-seq) methods allows for precise analysis of DNA methylation patterns at the i

academic.oup.com

CBMR's Zach Gerhart-Hines is awarded the first Flemming Quaade Prize for Outstanding Obesity Research for his pioneering discoveries on how fat tissue influences insulin sensitivity, energy expenditure, and appetite control. Read more: cbmr.ku.dk/news/2025/za... #obesity #metabolism

Check out our latest preprint from the lab, spearheaded by researcher @itsmedipsikha.bsky.social , investigating the distinctive roles of regulatory gamma subunits of the AMPK protein complex in small molecule activator-stimulated skeletal muscle glucose uptake. www.biorxiv.org/content/10.1...

Common and distinct roles of AMPKγ isoforms in small-molecule activator-stimulated glucose uptake in mouse skeletal muscle

Objective: Small-molecule activators targeting the allosteric drug and metabolite (ADaM) site of AMPK enhance insulin-independent glucose uptake in skeletal muscle and lower glucose in preclinical mod...

biorxiv.org