🎉 Congratulations to Pippa Wittenberg from the Gourine Lab for receiving the Early Investigator Prize!

The Journal of Physiology@jphysiol.bsky.social · last mo.

🏆 Congratulations to Philippa Wittenberg, winner of our 2025 #EarlyInvestigatorPrize in the Cardiovascular category! Her prize-winning research provides new insights into how intracranial baroreceptors may regulate blood pressure. 📖 Read more👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...

📣 New preprint out from the Adriaenssesns lab led by @nataliefigueredob.bsky.social Congratulations to all authors!

Natalie Figueredo Burgos@nataliefigueredob.bsky.social · 2mo ago

Really excited to share our new bioRxiv preprint! 🎉 www.biorxiv.org/content/10.6... In this study, we dissect the roles of GIPR neurons in two adjacent brainstem nuclei, the area postrema (AP) and nucleus tractus solitarius (NTS), and show that they have opposing effects on feeding.

Many congratulations to @uclnpp.bsky.social PhD student Alex Mascarenhas from @ccmnlondon.bsky.social He's just won best talk at ICBEM in Barcelona Exciting work on the role of astrocytes in hypoxia and a great achievement for a young scientist 💫

We're excited to announce that we're recruiting for new academic posts in #AI for #Biodiversity Science, Future #Food Systems & #Health, #NeuroAI, Computational #Neuroscience, and #Cardiovascular/Metabolic Neuroscience. 📅 Apply by 10 July 2026. www.ucl.ac.uk/life-science...

Lectureship being advertised at @ccmnlondon.bsky.social, @uclnpp.bsky.social, @ucl.ac.uk Don't miss this unusual opportunity to bag a job at a world leading institution! www.ucl.ac.uk/work-at-ucl/... Profs. Alexander Gourine and Stefan Trapp have an incredible research agenda 👀 #neuroskyence

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

Our Faculty is #hiring multiple academics posts! Includes a fantastic opportunity to join us and start your own group in @ccmnlondon.bsky.social as Lecturer in Cardiovascular or Metabolic Neuroscience (broadly defined). Contact me with any queries, and pls share! 🧠📈 www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

UCL Faculty of Life Sciences@ucllifesciences.bsky.social · 3mo ago

We're excited to announce that we're recruiting for new academic posts in #AI for #Biodiversity Science, Future #Food Systems & #Health, #NeuroAI, Computational #Neuroscience, and #Cardiovascular/Metabolic Neuroscience. 📅 Apply by 10 July 2026. www.ucl.ac.uk/life-science...

📣 Join us for the next CCMN Lecture as we welcome Dr. Frank Duca for an insightful talk on: 🧠 Impact of the diet-gut microbiome interactions on gut-brain axis regulation of metabolic disease 📅 Monday 15th June ⏰ 1:00 PM 📍 G01 Lankester Lecture Theatre, Medawar Building, UCL

📣 For our next CCMN seminar, we are pleased to welcome Dr. Hannah Botfield from the University of Birmingham, who will be presenting on: 🧠 Modulating CSF dynamics for stroke and hydrocephalus therapy 📅 Wednesday 22nd April ⏰ 1:00 PM 📍 CABI Seminar Room, Paul O’Gorman Building

New online! The critical role of gut–brain signalling in eating behaviour and obesity

The critical role of gut–brain signalling in eating behaviour and obesity

Nature Reviews Gastroenterology & Hepatology, Published online: 21 April 2026; doi:10.1038/s41575-026-01203-xThis Review outlines the role of gut–brain signalling in eating behaviour and obesity, highlighting gut-derived signals and cues relevant during eating phases. Underlying mechanisms of this gut–brain communication are discussed alongside the key role of the vagus nerve in this process.

dlvr.it

Really pleased to share our review of evidence for the diverse roles of the #vagus in each phase of eating behaviour, and our thoughts on how dysfunctional vagal #interoception drives obesity pathogenesis. Hope it provokes some thoughts, and many experiments! 🧠📈 🧪 www.nature.com/articles/s41...

The critical role of gut–brain signalling in eating behaviour and obesity - Nature Reviews Gastroenterology & Hepatology

This Review outlines the role of gut–brain signalling in eating behaviour and obesity, highlighting gut-derived signals and cues relevant during eating phases. Underlying mechanisms of this gut–brain ...

nature.com

👇 Great advice! 👇

British Society for Neuroendocrinology@bsneuroendo.bsky.social · 5mo ago

"The best thing in science is to be a good person. Stay curious, and follow your passions. Life is too short to waste time on something you are not really interested in." – Dave Grattan #BSNMentorTips - www.neuroendo.org.uk... Find your mentor: www.neuroendo.org.uk...

📣 New paper out from @trapp-lab.bsky.social led by @wanqingjiang.bsky.social. Big congratulations to all authors!

Trapp Lab@trapp-lab.bsky.social · 6mo ago

Our latest work published in Molecular Metabolism www.sciencedirect.com/science/arti... a great team effort with @wanqingjiang.bsky.social, @ceciliaskoug.bsky.social, @drdanbrierley.bsky.social, @ccmnlondon.bsky.social, @uclnpp.bsky.social, @mkbholt.bsky.social and our collaborators at Cambridge.

The CCMN Lecture Series is back! 🔬✨ We are excited to welcome Monica Imbernon from Queen Mary University of London,who will be speaking on: 🧠 ‘The involvement of the circumventricular organs in energy homeostasis’ 📅 Wednesday 18th March ⏰ 2:00 PM 📍 Medical Sciences 131 A V Hill Lecture Theatre

Happy Holiday Season to all friends, colleagues, collaborators and competitors! May the GLP-1 field stay as exciting in 2026 as it was in 2025!

📣 New preprint out from the Trapp lab!

Trapp Lab@trapp-lab.bsky.social · 9mo ago

We would like to share our findings of the physiological importance of brainstem GLP-1 neurons (also known as PPG or GCG neurons) and invite thoughts on this. www.biorxiv.org/content/10.6...

📣 New review out from @trapp-lab.bsky.social! Read to learn about the physiology and anti-obesity potential of preproglucagon neurons 🧠 Link here: academic.oup.com/endo/article...

Brain-Derived GLP-1—Understanding the Physiological Function and Anti-obesity Potential of Preproglucagon Neurons

Abstract. Glucagon-like peptide-1 (GLP-1) is produced within the central nervous system (CNS) by preproglucagon (PPG) neurons. This brain-derived GLP-1, ra

academic.oup.com

Thanks to @theiups.bsky.social 2025 meeting for a great Vascular Health and Function session where I was pleased to share exciting new data!

Cecilia Skoug@ceciliaskoug.bsky.social · 12mo ago

Another day, another excellent talk from a @ccmnlondon.bsky.social member. Dr. Anna Robert’s from @adriaenssenslab.bsky.social lab presented her work on GIP and vascular health here at @theiups.bsky.social 2025 meeting in Frankfurt.

Dr Cecilia Skoug presenting the latest mouse behaviour data from the Trapp lab at @theiups.bsky.social. Great presence from @ccmnlondon.bsky.social at a fantastic meeting!

Another day, another excellent talk from a @ccmnlondon.bsky.social member. Dr. Anna Robert’s from @adriaenssenslab.bsky.social lab presented her work on GIP and vascular health here at @theiups.bsky.social 2025 meeting in Frankfurt.

More @ccmnlondon.bsky.social representation at #IUPS2025; Philippa Wittenberg, PhD student in Prof. Alex Gourine’s group presented her work on the baroreceptor mechanism.

Last conference for the year for me is IUPS 2025. Yesterday was the well-attended symposium ”GLP-1 Receptor Agonists - a Magic Bullet Beyond Diabetes and Obesity?” Chaired by Prof. Stefan Trapp @trapp-lab.bsky.social Maybe I’m biased but a great symposium indeed! @ccmnlondon.bsky.social

Proud PI moment #1: @phoebeclax.bsky.social doing a stellar job in her first ever conference poster session, presenting data generated during her @bsneuroendo.bsky.social funded undergraduate summer lab experience project. #BSNBradford2025

Proud PI moment #2: Superstar postdoc @laurenjonesucl.bsky.social absolutely smashing her first conference presentation of her fascinating data on #semaglutide mechanism of action. #BSNBradford2025

Pleased to share a new paper that I'm proud to have contributed to 🌟 Grateful for the chance to work with such a talented team 🙌

Trapp Lab@trapp-lab.bsky.social · last yr.

Interested in brain access for Tirzepatide-based drugs? Have a look at the fluorescent Tirzepatide analogue developed by Johannes Broichhagen and David Hodson @daveyboyhod.bsky.social‬ out now in Nature Metabolism www.nature.com/articles/s42.... Proud to contribute to this great multi-lab effort.

Really enjoyed working on this - big thanks to everyone involved!

Cell Metabolism@cp-cellmetabolism.bsky.social · last yr.

Online now: Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism

Interested in brain access for Tirzepatide-based drugs? Have a look at the fluorescent Tirzepatide analogue developed by Johannes Broichhagen and David Hodson @daveyboyhod.bsky.social‬ out now in Nature Metabolism www.nature.com/articles/s42.... Proud to contribute to this great multi-lab effort.

Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain - Nature Metabolism

A series of fluorescent probes is designed that act as dual agonists on both GLP1 and GIP receptors, and are used to image receptor binding activities in tissues and animals.

nature.com

📣 New paper out exploring brain access of Tirzepatide based fluorescent analogues! We are proud to have contributed to this multi-lab effort.

Nature Metabolism@natmetabolism.nature.com · last yr.

Unbelievably proud of @nataliefigueredob.bsky.social for winning the prestigious Bogue Fellowship 🌟 She'll be heading across the pond to train with the @zknight.bsky.social lab for 3 months. Exciting things to come for this bright young scientist 🧠. @uclnpp.bsky.social @ccmnlondon.bsky.social