Nature research paper: Endocannabinoids facilitate reward engagement through retrograde gain control go.nature.com/4iwvL2x

Endocannabinoids facilitate reward engagement through retrograde gain control - Nature

A key role for retrograde neuromodulatory signalling in motivated behaviour is shown through dynamic endocannabinoid release within a thalamostriatal circuit that regulates behavioural engagement during reward seeking.

go.nature.com

Imaging activity in many defined cell types is now easi(er) using conventional 2p and confocal microscopes. 3000-5000 imaged neurons per recording, 78% matched to post hoc 3D EASI-FISH. We wanted this to be useful, affordable, and reliable. Jonna and an incredible team made it happen. Check it out!

Jonna Singh@jonnasingh.bsky.social · 4d ago

We're excited to present EASI-PASS! We can record the activity of many neurons, and separately, the expression of many genes. A natural next step for the field is to link these two types of information. 🧵👇 1/n

Registration for #NeuroendoCelebrate2026 has reopened for a limited time! We're delighted more of our members can join us in Manchester on 2-3 Sept for in-person collab, networking+engagement within our supportive society. Register by midnight,24.8.26: neuroendo.org.uk/Neu...

Stuart Firestein's new book, It Could Be Otherwise, is out. It completes the trilogy that began with Ignorance and Failure. I read an early version and it is terrific. Firestein shows how science actually works, and he makes the case that uncertainty is a feature, not a bug.

On the cover of Science Signaling today, the final version of our initial investigation of functional differences between VTA glutamate-dopamine, nonglutamate-dopamine, and glutamate-only neurons www.science.org/doi/10.1126/...

Distinct properties of glutamate-dopamine, nonglutamate-dopamine, and glutamate-only ventral tegmental area neurons

Glutamate cotransmission predicts the behavioral functions and characteristics of dopaminergic neurons in the VTA.

science.org

I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...

Some Tips for Writing Science

When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...

doi.org

Excellent reporting on astrocyte-engram work from @junnagai.bsky.social, @m-r-williamson.bsky.social and others. This article captures just how much of a frontier research area astrocyte engrams represent, and I’m excited to see how the field unfolds. www.thetransmitter.org/memory/are-p...

Are parts of the memory trace found in the ‘astroengram?’

Neurons have long taken top billing in memory, but researchers are making the case for astrocytes.

thetransmitter.org

Establish your lab in our department! We're looking for new colleagues doing exciting science. Come join a broad department interested in all aspects of biology from biomechanics of fossils (and live cells) to neuro-AI, via (of course!) the many facets of modern developmental biology.

UCL Centre for Integrative Anatomy@ucl-c4ia.bsky.social · 4w ago

🚀 The Cell & Developmental Biology (CDB) department is now inviting expressions of interest from early career researchers seeking sponsorship for external fellowships to establish their own independent research group. 📅 Deadline: 31 August 2026, 5:00 PM Apply here: www.ucl.ac.uk/life-science...

Found a neuroendo lab whose work you love❤️? Get up to £6000 support for travel and accommodation with our research visit grant Apply: neuroendo.org.uk/grants Deadline: 1 September 2026

This looks very cool and super useful for so many applications!

Jonas Wietek@jwietek.bsky.social · 4w ago

light-activated tetanus neurotoxin (LATeNT) by the @aliceyting.bsky.social lab. Includes a comparison with the light-switchable PdCO (www.nature.com/articles/s41...), showing a long lasting inhibition for 1h hour post illumination. www.nature.com/articles/s41...

Great to see our article out in this month's issue of @natrevgastrohep.nature.com, and pleasant surprise to have it chosen for the cover, and made available for free access! www.nature.com/articles/s41... www.nature.com/nrgastro/vol...

🧬 We're hiring. We’re excited to be recruiting for a Lecturer / Associate Professor in Primate or Human Evolutionary Anatomy to join the Centre for Integrative Anatomy at UCL. 📍 Location: London (hybrid) 📅 Closing date: 20 July 2026 MONDAY 👉 Apply here: www.jobs.ac.uk/job/DRZ412/l...

Lecturer / Associate Professor in Primate or Human Evolutionary Anatomy at UCL

Apply for the Lecturer / Associate Professor in Primate or Human Evolutionary Anatomy role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

jobs.ac.uk

Thoroughly enjoyed chatting all things GLP-1 with Simon Gaisford, Ahad Rahim and Stefan Trapp on forthcoming podcast for @ucllifesciences.bsky.social - watch this space!

I am happy to share our latest manuscript, led by newly-minted PhD Justin Wang, identifying a neural population that selectively controls hedonic, but not homeostatic, feeding. www.biorxiv.org/content/10.6...

Ventral pallidal GABAergic neurons control hedonic feeding and obesity

Food intake is governed by two interacting drives. The homeostatic hunger drive regulates food intake to fulfill caloric needs while the hedonic drive promotes intake of palatable foods outside of cal...

biorxiv.org

Autonomic C1 neurons promote anxiety via activation of vlPAG: Neuron www.cell.com/neuron/fullt...

Autonomic C1 neurons promote anxiety via activation of vlPAG

Fernández-Peña et al. used viral intersectional tools to selectively target epinephrine-expressing C1 neurons in mouse rostral ventrolateral medulla (RVLM). Adjusting their activity altered the severi...

cell.com

Looking for a postdoc? The @sciolinolab.bsky.social at UConn is hiring! We investigate how neuromodulatory systems interact with central taste processing regions to regulate behavior using in vivo recordings, optogenetics & mouse behavior. Apply: jobs.hr.uconn.edu/en-us/job/49...

18 months after starting our first Early Career Editorial Board at JNE, board members like @isadoracfurigo.bsky.social reflect on how the experience is equipping them with the tools to excel in their careers: www.neuroendo.org.uk... Keep an eye out for the next enrolment coming soon!

Great reporting on this perspective in Science: www.science.org/doi/10.1126/... 1. Risks of ultra-processed foods are likely caused by their differences in specific nutritional properties, not in being 'processed' 2. 'Ultra-processed' miscategorizes many healthy + sustainable plant-based products

Ultraprocessed foods and obesity: Interpreting the evidence

What do randomized controlled trials really tell us about the effects of ultraprocessed foods?

science.org

Vox@vox.com · 2mo ago

New analysis suggests other factors may explain the harms blamed on “ultra-processing.” www.vox.com/future-perfe...

1 week left to apply for the new Lecturer position in the UCL Centre for Cardiovascular and Metabolic Neuroscience. If you / anyone you know works in this field (broadly defined) and is looking to start their own lab, please consider applying! Please share! 📈🧠 www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

We are seeking healthy individuals to take part in a Johns Hopkins research study. The study will look at the effects of psilocybin, a psychedelic drug, with pindolol (a medication that blocks a serotonin receptor).

📢 Limited poster presentation slots reopened! Showcase your work + get feedback from senior scientists at our Early Career Researcher Meeting, #NeuroendoCelebrate2026 in Manchester, 2-3 Sept. Submissions close once all slots have been filled. SUBMIT: neuroendo.org.uk/Neu...

Please sign!

Francesca Stavrakopoulou@proffrancesca.bsky.social · 2mo ago

I’d love it if you’d sign this. It might not prevent me and my colleagues losing our jobs, but it will draw attention to the ideological vandalism being perpetrated by the wealthy execs running our university. Stop Redundancies at the University of Exeter - sign the petition below! c.org/NpvY4sR9gH

Are you working on a neuroendocrine research project?🧠🔬 💸Get up to £8,000 support for consumables/other research costs to enable you to carry out the best possible neuroendocrine research project. Deadline 31 July Apply: neuroendo.org.uk/grants

Exciting #PhD opportunity (UK students only) with our new departmental colleague Janin @lautenschlagerlab.bsky.social - great opportunity! 📈🧠 www.findaphd.com/phds/project...

Alpha-Synuclein Condensates and Synaptic Dysfunction in Parkinson’s Disease at University College London on FindAPhD.com

PhD Project - Alpha-Synuclein Condensates and Synaptic Dysfunction in Parkinson’s Disease at University College London, listed on FindAPhD.com

findaphd.com

UCL is hiring for 5 new positions! Individual job details below!👇 #ScienceJobs

Our CeA GLP-1 story is now online. We've got a lot more cooking in this area and I think this will inform future circuit-guided GLP-1 therapeutics: www.sciencedirect.com/science/arti... Great job to my first PhD student, Miguel Duran, who has had a hell of a week.

The central amygdala gates exogenous glucagon-like peptide 1 signals

Nuclei within the limbic system like the central amygdala (CeA) play a critical role in mediating fear, motivation, reward, and appetitive behavior. A…

sciencedirect.com

Andrew Hardaway@andrewhardaway.bsky.social · 5mo ago

Really thrilled to share my lab's latest work where we characterize the role of the CeA in integrating exogenous GLP-1 signals. www.biorxiv.org/content/10.6...

Job klaxon 📣 UCL is hiring two NeuroAI / computational neuroscience specialists (Lecturer or Associate Prof) — a big part of the new NeuroAI centre we're growing in Biosciences. Do consider applying if it's relevant to you. JD & details: https://www.jobs.ac.uk/job/DRX021 Happy to take questions.

Lectureship being advertised at @ccmnlondon.bsky.social, @uclnpp.bsky.social, @ucl.ac.uk Don't miss this unusual opportunity to bag a job at a world leading institution! www.ucl.ac.uk/work-at-ucl/... Profs. Alexander Gourine and Stefan Trapp have an incredible research agenda 👀 #neuroskyence

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

THIS IS AN IMPORTANT PAPER FOR TRANSLATIONAL-CIRCUIT-BASED THERAPEUTICS Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model: Cell www.cell.com/cell/fulltex...

Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model

An AAV-based circuit modulation approach that consists of a designer retrograde AAV capsid, a medium spiny neuron-enriched promoter, and a selected chemogenetic effector specifically modulates direct ...

cell.com